雖然這篇GLI2鄉民發文沒有被收入到精華區:在GLI2這個話題中,我們另外找到其它相關的精選爆讚文章
[爆卦]GLI2是什麼?優點缺點精華區懶人包
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#1GLI2 - Wikipedia
Zinc finger protein GLI2 also known as GLI family zinc finger 2 is a protein that in humans is encoded by the GLI2 gene. ... The protein encoded by this gene is a ...
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#2GLI2 Gene - GeneCards | GLI2 Protein | GLI2 Antibody
GLI2 (GLI Family Zinc Finger 2) is a Protein Coding gene. Diseases associated with GLI2 include Culler-Jones Syndrome and Holoprosencephaly ...
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#32736 - Gene ResultGLI2 GLI family zinc finger 2 [ (human)]
2022年2月13日 — GLI2 is a dosage-sensitive gene that may be responsible for the agenesis of corpus callosum observed in the proband. This inhibitory effect on ...
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#4Zinc finger protein GLI2 - Homo sapiens (Human) - UniProt
Acts as a transcriptional activator in T-cell leukemia virus type 1 (HTLV-1)-infected cells in a Tax-dependent manner. Binds to the DNA sequence 5'-GAACCACCCA-3 ...
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#5GLI2 - an overview | ScienceDirect Topics
GLI2 is a transcription factor that mediates Sonic hedgehog signaling, an important regulator of early Rathke's pouch development, and proliferation of ...
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#6GLI2 protein expression summary
Gene name, GLI2 (HGNC Symbol). Synonyms, HPE9, THP1, THP2. Description, GLI family zinc finger 2 (HGNC Symbol). Chromosome, 2. Cytoband, q14.2.
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#7GLI2 (GLI family zinc finger 2) - Atlas of Genetics and ...
GLI2 is one of the components of Hedgehog signaling and one of the three zinc finger transcription factors involved in this signaling pathway. GLI2 is thought ...
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#8165230 - GLI-KRUPPEL FAMILY MEMBER 2; GLI2 - OMIM
The GLI2 gene encodes a vertebral transcription factor involved in SHH (600275) signal transduction (Roessler et al., 2003).
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#9MGI:95728 - GLI-Kruppel family member GLI2 - Mouse ...
View mouse Gli2 Chr1:118761862-118981349 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.
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#10GLI1/GLI2 functional interplay is required to ... - Portland Press
GLI3 functions mainly as a transcriptional repressor whereas GLI1 and GLI2 can function as activators, with GLI2 having a dual activator/ ...
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#11Anti-GLI-2 Antibody (C-10): sc-271786 - Santa Cruz ...
GLI-2 Antibody (C-10) is a monoclonal anti-GLI2 antibody that detects m, r, and h GLI-2 by WB, IP, IF, IHC(P) and ELISA. Cited in 36 publications.
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#12GLI2-Specific antibody (18989-1-AP) | Proteintech
Cited in 31 publications. GLI2-Specific antibody for IF, IHC, WB,ELISA and reacts with human, mouse, rat.
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#13Gene: GLI2 (ENSG00000074047) - Summary - Homo_sapiens
Gene: GLI2 ENSG00000074047 . twitter logo Twitter facebook logo Facebook email logo Email. Description. GLI family zinc finger 2 [Source:HGNC Symbol ...
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#14Mouse GLI-2 Antibody AF3635 - R&D Systems
GLI family zinc finger 2; GLI2; GLI-2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9tax helper protein 1; ...
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#15Anti-GLI2 antibody produced in rabbit - Sigma-Aldrich
Anti-GLI2 antibody produced in rabbit; Synonyms: PHS2,THP2,THP1,Gli2,GLI2,CJS,HPE9; find Sigma-Aldrich-SAB5700756 MSDS, related peer-reviewed papers, ...
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#16GLI2 Antibody (CF804549) - Thermo Fisher
OriGene Anti-GLI2 Monoclonal (OTI1F9), TrueMAB™, Catalog # CF804549. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications.
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#17Essential function of Gli2 and Gli3 in the formation of lung ...
A reduction of 50% in the gene dosage of Gli3 in a Gli2–/– background resulted in oesophageal atresia with tracheo-oesophageal fistula and a severe lung ...
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#18Anti-GLI2 | ABN2241 - EMD Millipore
Anti-GLI2, Cat. No. ABN2241, is a highly specific rabbit polyclonal antibody that targets Zinc finger protein GLI2 and has been tested in ...
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#19GLI2 (R770) Antibody#2585 - Cell Signaling Technology
GLI2 (R770) Antibody detects transfected levels of human GLI2 protein. Species Reactivity: Human. Source / Purification. Polyclonal antibodies are produced by ...
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#20Loss-of-function mutations in the human GLI2 gene ... - PNAS
Gli2 is one of three vertebrate transcription factors implicated as obligatory mediators of Shh signal transduction. ... We also demonstrate that ...
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#21Anti-Gli2 antibody [OTI1F9] (ab187386) | Abcam
Mouse monoclonal Gli2 antibody [OTI1F9]. Validated in WB, IHC and tested in Human. Cited in 5 publication(s). Immunogen corresponding to recombinant ...
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#22GLI2 Gene Set - Ma'ayan Laboratory - Computational Systems ...
80 target genes of the GLI2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription ...
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#23The Biochemistry and Regulation of GLI2 - FullText - Karger ...
GLI2 is an oncogene encoding a unique transcription factor with both repressor and activator functions. Vitally important in development, ...
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#24Sonic hedgehog-dependent activation of Gli2 is essential for ...
Similar toShh −/− mice, Gli2 −/− mutants exhibit an arrest in hair follicle development with reduced cell proliferation and Shh-responsive gene expression, ...
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#25GLI2 Antibody - middle region (ARP31885_T100) - Aviva ...
GLI2 Antibody - middle region (ARP31885_T100), Catalog ARP31885_T100. Tested in IHC, WB applications. Reacts with Human samples. Liquid.
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#26GLI-2 Antibody (NB600-874) - Novus Biologicals
The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli2 is also thought to play a role ...
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#27Unique and overlapping GLI1 and GLI2 transcriptional targets ...
Our identification of potential target genes that are unique and common to GLI1 and GLI2 in neoplastic chondrocytes contributes to elucidating ...
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#28Role of GLI2 in hypopituitarism phenotype in - Journal of ...
GLI2 is a zinc-finger transcription factor involved in the Sonic Hedgehog pathway. Gli2 mutant mice have hypoplastic anterior and absent posterior pituitary ...
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#29GLI2 (human) - PhosphoSite
GLI2 Functions as transcription regulator in the hedgehog (Hh) pathway. · Protein type: C2H2-type zinc finger protein; Oncoprotein; Transcription factor.
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#30Human Gene GLI2 (ENST00000452319.6) from GENCODE V38
Description: Homo sapiens GLI family zinc finger 2 (GLI2), transcript variant 2, mRNA. (from RefSeq NM_005270) RefSeq Summary (NM_005270): This gene encodes ...
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#31GLI2 inhibition abrogates human leukemia stem cell dormancy
In summary, while GLI2, forms part of a core HH pathway transcriptional regulatory network that promotes human myeloid leukemic progression ...
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#32GLI2 gene
GLI2 (#165230). Function of gene/protein. Protein: GLI family zinc finger 2; Regulates other genes by binding to specific DNA regions ...
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#33Sonic hedgehog Signaling Regulates Gli2 Transcriptional ...
ABSTRACT Gli2 and Gli3 are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse.
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#34Functional Characterization of a Heterozygous GLI2 Missense ...
Context:. The GLI2 transcription factor is a major effector protein of the sonic hedgehog pathway and suggested to play a key role in pituitary development.
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#35Gli2 as a mediator of Shh signaling - Journals Gateway | The ...
Mouse embryos homozygous for Gli2 mutations display diminished expression of Shh target genes, Ptc and Gli1, and lack a floor plate in the neural tube (Ding ...
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#36GLI2 - DECIPHER v11.9
GLI2 2:120735623-120992653. Forward strand gene: GLI family zinc finger 2. Also known as: THP1, HPE9, THP2, ENSG00000074047.
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#37GLI2 - LSBio
GLI2. GLI family zinc finger 2. GLI2 is a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family.
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#38anti-GLI2 antibody (ARG56582) - arigo Biolaboratories
anti-GLI2 antibody is a Rabbit Polyclonal antibody recognizes GLI2, which can be used for Flow cytometry,ICC/IF,Western blot testing with Human samples.
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#39Hedgehog signaling via Gli2 prevents obesity induced by high ...
Targeted activation of Hedgehog signalling via Gli2 facilitated the reduction of high-fat-diet-induced obesity and improvement of whole-body ...
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#40pCS2-MT GLI2 delta N (Plasmid #17649) - Addgene
Plasmid pCS2-MT GLI2 delta N from Dr. Erich Roessler's lab contains the insert GLI2 and is published in Hum Mol Genet. 2005 Aug 1. 14(15):2181-8.
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#41GLI2 | Cancer Genetics Web - CancerIndex
Gene: GLI2; GLI family zinc finger 2 ... Protein: zinc finger protein GLI2 ... RESULTS: Overexpression of the Hedgehog signaling components SHH and GLI2 and ...
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#42Role of GLI2 Transcription Factor in Growth and ...
Aberrant activation of the Hedgehog (Hh) signaling pathway has been reported in various cancer types including prostate cancer. The GLI2 ...
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#43GLI2 but not GLI1/GLI3 plays a central role in the induction of ...
GLI2 is involved in cell cycle-mediated proliferation in GBC. Protein expression of the transcription factors GLI1, GLI2, and GLI3 and Hh signal ...
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#44The transcription factor GLI2 as a downstream mediator of ...
Fibroblast-specific knockout of GLI2 protected mice from TBR act -induced fibrosis. Combined targeting of canonical and non-canonical hedgehog signalling with ...
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#45Differential requirements for Gli2 and Gli3 in the regional ...
Secreted protein Sonic hedgehog (Shh) ventralizes the neural tube by modulating the crucial balance between activating and repressing ...
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#46GLI2 (NM_005270) Human Tagged ORF Clone - OriGene
GLI2 (Myc-DDK-tagged)-Human GLI family zinc finger 2 (GLI2)
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#47GLI2 Rabbit pAb (A16864) - Polyclonal Antibodies - ABclonal
Immunofluorescence analysis of L-929 cells using GLI2 antibody (A16864) at dilution of 1:100. Blue: DAPI for nuclear staining.
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#48anti-GLI2 antibody (Middle Region) | Product No. ABIN2777474
GLI2 antibody (GLI Family Zinc Finger 2) Middle Region Primary Antibody. GLI2 Reactivity: Human IHC, WB Host: Rabbit Polyclonal unconjugated.
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#49Relative Levels of Gli1 and Gli2 Determine the ... - Cell Press
GLI1 and GLI2 act as major transcriptional activators of the Sonic hedgehog (Shh) pathway, but have different expression patterns in the SVZ ( ...
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#50Gli2 Influences Proliferation in the Developing Lung through ...
The sonic hedgehog (Shh) signaling pathway is crucial for normal lung development. In the lung, epithelial-produced Shh signals via ...
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#51- GLI2 antibodies | Antibodypedia
GLI2. gene product. HPE9, THP1, THP2. This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family.
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#52Anti GLI2 Antibody (PrecisionAb Polyclonal Antibody) | Bio-Rad
GLI2 antibody for detecting the human zinc finger protein GLI2. Validated on up to 12 cell lysates for western blotting. Try a trial size today.
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#53GLI2 - My Cancer Genome
GLI2 is altered in 3.26% of all cancers with lung adenocarcinoma, colon adenocarcinoma, melanoma, breast invasive ductal carcinoma, and cutaneous melanoma ...
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#54Ihh/Gli2 Signaling Promotes Osteoblast Differentiation by ...
Ihh treatment or Gli2 overexpression also up-regulated the expression of Runx2, an essential transcription factor for osteoblastogenesis, and enhanced the ...
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#55GLI2 CRISPR guide RNA - GenScript
The GLI2 CRISPR guide RNA sequences were designed by GenScript's proprietary algorithm to target a single locus in the endogenous genome.
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#56Tumor Microenvironment: State of the Science
the regulation of GLI2 expression modulated the expression of IL-6 [27, 28]. IL-6 is a cytokine with a well-established role in normal and malignant B cells ...
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#57Aberrantly activated Gli2-KIF20A axis is crucial for growth of ...
Glioma-associated oncogene 2 (Gli2), a primary transcriptional regulator of Hedgehog (Hh) signaling, is essential for hepatocellular ...
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#58Degradation of GLI2 by the proteasome - Reactome
The primary role of the GLI2 protein is as an activator of Hh-dependent signaling upon pathway stimulation; in the absence of Hh ligand, a small fraction of ...
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#59Gli2 and Gli3 Are Over-expressed in the Ischemic Tissue and ...
Gli transcription factors are mediators of hedgehog signaling and have been shown to be critical in several steps during development.
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#60Modulation of the IL-6 Receptor α Underlies GLI2-Mediated ...
In this study, we define a novel pathway involving the oncogenic transcription factor GLI2 modulating IgM secretion by WM malignant cells.
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#61GLI2 mutant p.P1167LfsX52 lacks transcriptional activity and ...
Background GLI2 encodes for a transcription factor that controls the expression of several genes in the Hedgehog pathway. Mutations in GLI2 have been described ...
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#62Gli2 - MMRRC
Gli2 Gene Details Email me when MMRRC products with Gene Gli2 become available. Name, GLI-Kruppel family member GLI2. Species, Mus musculus (mouse).
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#63GLI2, An Effector of the Hedgehog Pathway, Is a Novel ...
GLI2, An Effector of the Hedgehog Pathway, Is a Novel Regulator of IL6 Oncogenic Function In the Tumor Microenvironment ... Blood (2010) 116 (21): ...
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#64Gli2 and Gli3 have redundant and context-dependent function ...
expression pattern and the regulation of Gli1, Gli2, and Gli3 during somite formation in the mouse embryo. We also carried out genetic studies using Gli and ...
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#65GLI1/GLI2 functional interplay is required to control Hedgehog ...
The Hedgehog-regulated transcription factors GLI1 and GLI2 play overlapping roles in development and disease; however, the mechanisms underlying their ...
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#66GLI2 | Gene - VarSome
Zinc finger-containing Gli proteins mediate responsiveness to Hedgehog (Hh) signaling, with Gli2 acting as the major transcriptional activator in this ...
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#67Pharmacological GLI2 inhibition prevents myofibroblast ... - JCI
Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis. Rafael Kramann, 1,2 Susanne V. Fleig, 1 ...
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#68Preclinical and clinical impact of the GLI2 transcription factor ...
The automated quantitative analysis system (AQUA) was used to assess protein expression of GLI2 in NSCLC specimens from 88 deceased patients ( ...
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#69Gli2-regulated activation of hepatic stellate cells and liver ...
Gli2 is a key transcription effector of Hh signaling. We found that Hh/Gli2 signaling activity was upregulated in CCl4-induced liver ...
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#70GLI2 - Gene - Invitae
The GLI2 gene is associated with autosomal dominant Culler-Jones syndrome (MedGen UID: 862916) and autosomal dominant holoprosencephaly (MedGen UID 324369).
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#71Issues in Development and Developmental Disorders: 2011 Edition
osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification A new study, 'Gli2 activator function in ...
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#72GLI2基因详情-基因数据库-基因云馆
GLI2 的详细信息,包括基因名称,代码,染色体位置,相互作用关系和通路,简述为这个基因编码属于的Gli家族的C2H2型锌指蛋白亚类的蛋白。这个子类的成员被定性为它通过 ...
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#73Gli Proteins: Regulation in Development and Cancer - MDPI
Under these conditions, Gli2 and Gli3 are partially truncated on the C terminus, which removes their transcriptional activation domain and confers on them the ...
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#74GLI2-Mediated Inflammation in the Tumor Microenvironment
The transcription factor GLI2 was initially identified as a member of the Hedgehog (HH) signaling pathway. During the last decade, ...
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#75Role of the hedgehog signaling in bone homeostasis - Tulane ...
Full-length Gli2 is a powerful activator of BMP2 transcription, whereas truncated Gli3 acts as a strong BMP2 repressor in osteoblasts. We hence have named the ...
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#76Fuzzy modeling reveals a dynamic self-sustaining network of ...
The GLI transcription factors, GLI1, GLI2, and GLI3, transduce Hedgehog and non-hedgehog signals and are involved in regulating development and tumorgenesis ...
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#77Hedgehog Signaling - 第 298 頁 - Google 圖書結果
In vertebrates, three Gli proteins, Gli1, Gli2, and Gli3, are involved in the transcriptional control of Hh target genes. Each Gli protein is suggested to ...
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#78Cell Adhesion Molecules: Advances in Research and ...
Scientists discuss in 'GLI2-mediated melanoma invasion and metastasis' new findings in melanoma. “The transforming growth factor— beta (TGF-beta) pathway, ...
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#79GLI2 - Orphanet
The portal for rare diseases and orphan drugs · Search for a gene · GLI2 - GLI family zinc finger 2 · Diseases list.
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#80Issues in Clinical Medicine Research and Practice: 2013 Edition
GLI2. Missense. Mutation. in. Patients. With. Multiple. Pituitary ... Genomic GLI2 aberrations that mainly result in truncated proteins have been reported ...
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#81The Parathyroids: Basic and Clinical Concepts
Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol Biol Cell 2007;18:2411–8. Kronenberg HM.
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#82Shh and Gli Signalling in Development - 第 6 頁 - Google 圖書結果
All have activator function but only Gli2 and 3 have potent repressor functions, and each appears to be regulated differendy. Details of the role(s) of the ...
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#83View Image
Close. Indian J Med Microbiol. Figure 1: Identification of the NTD-associated SNP rs3738880 in the GLI2 gene. (a) Conserved domains of GLI2 and location of ...
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#84VW.com | Official Home of Volkswagen Cars & SUVs
Great news: the 2022 Atlas, Atlas Cross Sport, Tiguan, and Taos have lower cost of maintenance than their respective 2021 Toyota, Honda and Subaru competitors.
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#85Gnas Loss Causes Chondrocyte Fate Conversion in Cranial ...
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development. 129(20):4753–4761. Google ...
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#86Patrick Schweickert - Biological Scientist - Arcus Biosciences
... AKT and noncanonical activation of the GLI family transcription factor GLI2. GLI2 was phosphorylated at Ser230 in an AKT-dependent fashion and directly ...
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#87BibMe: Free Bibliography & Citation Maker - MLA, APA ...
BibMe Free Bibliography & Citation Maker - MLA, APA, Chicago, Harvard.
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#88TT
0T South Bend Clutch Stage 2 Clutch Upgrade -- Select Option-- MK5/MK6 Golf GTI/Jetta GLI 2. 5 TT RS has a different block, it's made to handle the boost.
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#89Fetal Therapy: Scientific Basis and Critical Appraisal of ...
Within the cell, the hedgehog signal is mediated via the zinc finger transcription factors Gli1, Gli2, or Gli3. Gli1 is a transcriptional activator whereas ...
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#90Endocrinology: Adult and Pediatric E-Book - 第 82 頁 - Google 圖書結果
One consequence of the Gli2 defect in yot-mutant zebrafish embryos was the absence of Lhx3 expression in the anterior part of the adenohypophysis anlage.141 ...
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#91Pompei. Terribile rapina in B&B, commando sequestra clienti ...
Una cliente è riuscita riesce a chiamare il 112, due gli 2 arresti. A Pompei i carabinieri della compagnia di Torre annunziata hanno ...
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#92GD - Industrial Product Supplier
... 2020 Ad Ref # 4612096 Toyota mark 2 7 Toyota from Rs. Toyota Mark ii Cng . 4L Manual UCR: FINAL Contender - 1989 Toyota Corona GLi 2.
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#93OH - SECRET CARNIVAL WORKERS
Used 2012 Volkswagen Touareg VR6 $11,319 152,542 mi. com I have for sale an excellent condition 2003 Volkswagen Jetta GLI 2. 1993 Volkswagen Corrado 1.
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#942-etilhexyle Oleate Mercato 2021: sviluppi futuri, strategia ...
L'analisi regionale aiuterà gli 2-etilhexyle Oleate attori del mercato ad attingere a mercati regionali non mappati, a preparare strategie ...
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#95Sarımsaklı Günlük Kiralık havuzlu Villa sabinegutsch.de
Toyota corolla 1.6 Gli 2. El Fiyatları Ayvalık Günlük Kiralık Villa Fiyatları ve Günlük Kiralık Villa İlanları sahibinden.com'da.
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#9611 - Nova-Tech FILTERS PVT. LTD.
Fits Arteon, Golf, GTI, Jetta, Jetta GLI 2 DOOR. Description: The Lower Door Sill provides the lower door lining with a custom, finished look as well as ...
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#97Adding
VW - MK6 JETTA & GLI 2. 8l EA888 engine As already described, in the summer of 2011 Audi put into production the third generation of its four-cylinder ...
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#98Hp - 411-Pain Alabama
Buy the 034Motorsport R410 Turbo Upgrade Kit & Tuning Package for 8J/8P Audi TT/A3 & MkV Volkswagen GTI/GLI 2. In addition, the engine ...
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