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#1GLI1 - Wikipedia
Zinc finger protein GLI1 also known as glioma-associated oncogene is a protein that in humans is encoded by the GLI1 gene. It was originally isolated from ...
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#22735 - Gene ResultGLI1 GLI family zinc finger 1 [ (human)]
2022年1月25日 — Gli1 regulates stemness characteristics in gastric adenocarcinoma. Hedgehog Signaling and Truncated GLI1 in Cancer. Gli1 interacts with YAP1 to ...
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#3GLI1 Gene - GeneCards | GLI1 Protein | GLI1 Antibody
GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Polydactyly, Postaxial, ...
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#4Zinc finger protein GLI1 - Homo sapiens (Human) - UniProt
Acts as a transcriptional activator, but activates a different set of genes than isoform 1. Activates expression of CD24, unlike isoform 1. Mediates SHH ...
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#5GLI1: A Therapeutic Target for Cancer | Oncology - Frontiers
GLI1 is a transcriptional effector at the terminal end of the Hedgehog signaling (Hh) pathway and is tightly regulated during embryonic ...
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#6GLI1 protein expression summary
Gene name, GLI1 (HGNC Symbol). Synonyms, GLI. Description, GLI family zinc finger 1 (HGNC Symbol). Chromosome, 12. Cytoband, q13.3.
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#7GLI1 (glioma-associated oncogene homolog 1) - Atlas of ...
GLI1 (glioma-associated oncogene homolog 1) · Germinal, An abnormal activity of GLI, caused by mutations affecting upstream components of the sonic hedgehog- ...
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#8GLI1 - an overview | ScienceDirect Topics
GLI1 is a cysteine-rich protein (28 total residues) and has five zinc finger binding domains that contain cysteine residues. Given the evidence, it is highly ...
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#9GLI1 - My Cancer Genome
GLI1 family zinc finger 1 (GLI1) is a gene that encodes a protein that functions as a transcription factor protein. The protein is activated by the sonic ...
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#10Role and inhibition of GLI1 protein in cancer | LCTT - Dove ...
Abstract: GLI1 is a transcriptional regulator involved in the development of different types of cancer. GLI1 transcriptional activity is ...
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#11Zinc finger protein GLI1 (IPR032850) - InterPro entry - EMBL-EBI
GLI1 (glioma-associated oncogene homologue 1) is a central effector of the Hedgehog (HH) pathway, a pathway that governs many developmental processes ·. It is a ...
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#12gli1 - ZFIN Gene
gli1. ID: ZDB-GENE-030321-1; Name: GLI family zinc finger 1; Symbol: gli1 Nomenclature History; Previous Names. detour; dtr.
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#13008211 - Gli1[lz] Strain Details - The Jackson Laboratory
These lacZ reporter mutant mice harbor a β-galactosidase "knock-in" mutation that also abolishes endogenous GLI-Kruppel family member GLI1 ...
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#14GLI1 (human) - PhosphoSite
GLI1 Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal ...
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#15Gene: GLI1 (ENSG00000111087) - Summary - Ensembl
Gene: GLI1 ENSG00000111087 . twitter logo Twitter facebook logo Facebook email logo Email. Description. GLI family zinc finger 1 [Source:HGNC Symbol ...
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#16GLI1 Antibody (MA5-26638) - Thermo Fisher
Invitrogen Anti-GLI1 Monoclonal (OTI4E2), Catalog # MA5-26638. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications.
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#17Noncanonical GLI1 signaling promotes stemness features ...
In LAC cells including the cancer stem cell compartment, we show that GLI1 is activated noncanonically by MAPK/ERK signaling. Different ...
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#18Anti-GLI-1/GLI1 Antibody (C-1): sc-515751 - Santa Cruz ...
GLI-1/GLI1 Antibody (C-1) is a monoclonal anti-GLI-1 antibody that detects m, r, and h GLI-1 by WB, IP, IF and ELISA. Cited in 27 publications.
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#19OMIM Entry - * 165220 - GLI FAMILY ZINC FINGER 1; GLI1
165220 - GLI FAMILY ZINC FINGER 1; GLI1 - GLIOMA-ASSOCIATED ONCOGENE HOMOLOG;; ONCOGENE GLI; GLI - GLI1.
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#20GLI1/GLI2 functional interplay is required to control Hedgehog ...
GLI1 and GLI2 were shown to co-immunoprecipitate in PANC1 pancreatic cancer cells and RMS13 rhabdomyosarcoma cells. Mapping analysis ...
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#21GLI1 Antibody#2553 - Cell Signaling Technology
GLI1 Antibody detects endogenous levels of total GLI1 protein. Species Reactivity: Human. Source / Purification. Polyclonal antibodies are produced by ...
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#22Unique and overlapping GLI1 and GLI2 transcriptional targets ...
These transcription factors regulate expression of Hh target genes, including pathway members Gli1 and Ptch1, through a consensus binding motif ...
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#23Anti-Gli1 antibody (ab167388) | Abcam
Rabbit polyclonal Gli1 antibody. Validated in WB and tested in Mouse. Cited in 1 publication(s). Independently reviewed in 1 review(s).
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#24Degradation of GLI1 by the proteasome - Reactome
Although GLI1 is dispensible for development, the gene is an early transcriptional target of Hh signaling and the protein contributes a minor activation ...
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#25GLI1 Gene Set - Ma'ayan Laboratory - Computational Systems ...
63 target genes of the GLI1 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor ...
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#26Gli1/DNA interaction is a druggable target for Hedgehog ...
Remarkably, as a consequence of its robust inhibitory effect on Gli1 activity, Glabrescione B inhibited the growth of Hedgehog-dependent tumor cells in vitro ...
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#27GLI1 antibody (66905-1-Ig) | Proteintech
GLI1, also known as Glioma-associated oncogene, is a 1106 amino acid protein, which belongs to the GLI C2H2-type zinc-finger protein family. GLI1 is detected in ...
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#28Gli1 - bionity.com
Gli1 glioma-associated oncogene homolog 1 (zinc finger protein) Identifiers Symbol GLI1 Alt. Symbols GLI Entrez 2735 HUGO 4317 OMIM 165220 RefSeq NM_005269.
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#29GLI1 is regulated through Smoothened-independent ...
Pancreatic ductal adenocarcinoma (PDAC) is characterized by the deregulation of the hedgehog signaling pathway. The Sonic Hedgehog ligand (Shh), absent in the ...
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#30Up-regulation of GLI1 in vincristine-resistant ...
The clinical significance of GLI1 expression either through canonical Hedgehog signal transduction or through non-canonical mechanisms in ...
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#31GLI1 (NM_005269) Human Recombinant Protein – TP301110
Recombinant protein of human GLI family zinc finger 1 (GLI1)
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#32Gli1 Regulates the Postnatal Acquisition of Peripheral Nerve ...
Unexpectedly, Gli1 expression by endoneurial cells is independent of, and functions nonredundantly with, Schwann Cell-derived Desert Hedgehog in ...
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#33Gli1 (GLI family zinc finger 1) - Rat Genome Database
Symbol: Gli1. Name: GLI family zinc finger 1. RGD ID: 621673. Description: Predicted to enable several functions, including DNA-binding transcription factor ...
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#34Hedgehog Signaling and Truncated GLI1 in Cancer - MDPI
Consequently, the glioma-associated oncogene homolog 1 (GLI1) zinc-finger transcription factors, the terminal effectors of the HH pathway, are released from ...
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#35Gli1 can rescue the in vivo function of Gli2 - Journals Gateway ...
In particular, Gli1 appears to be a constitutive activator, and Gli2 and Gli3 have repressor functions. To determine the precise functional ...
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#36Regulation of Gli1 Localization by the cAMP/Protein Kinase A ...
Conversely, inhibition of PKA activity promotes nuclear accumulation of Gli1. Mutation analysis identifies Thr 374 as a major PKA site determining Gli1 protein ...
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#37GLI1 Inhibitors Identified by Target Protein Oriented Natural ...
(6) The key stem cell regulatory gene BMI1 was recently shown to be directly controlled by Hh signaling. (7) GLI1 binds to the promoter region ...
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#38Timed Induction of Gli1 (P3 To P30) Was Expressed In Mouse ...
Gli1 is downstream of the Sonic hedgehog (Shh) signaling pathway. This pathway is mediated by the Gli transcription factors (Gli1, Gli2, and ...
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#39Targeting GLI1 Suppresses Cell Growth and Enhances ...
Keywords: Acute myeloid leukemiaLeukemia progenitor cellHedgehog signaling pathwayGLI1Small-molecule inhibitorGANT61 ...
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#40Anti-GLI1 Antibody from rabbit, purified by affinity ...
Anti-GLI1 Antibody from rabbit, purified by affinity chromatography; Synonyms: Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI; ...
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#41Concomitant activation of GLI1 and Notch1 contributes to ...
Elucidation of GLI1-Notch1 axis as key determinant of racial disparity in TNBC growth in African American and White American women.
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#42GLI1 inactivation is associated with developmental ...
Abstract. GLI1, GLI2 and GLI3 form a family of transcription factors which regulate development by mediating the action of Hedgehog (Hh) morphogens.
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#43Relative Levels of Gli1 and Gli2 Determine the ... - Cell Press
In the healthy adult brain, ventral neural stem cells (vNSCs) in the subventricular zone, marked by GLI1 expression, do not generate oligoden-.
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#44Noncanonical Regulation of the Hedgehog Mediator GLI1 by c ...
Although Hedgehog signaling plays a major role in GLI1 ... We show that all Burkitt lymphoma cell lines tested express GLI1, PTCH1, ...
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#45Trisomy 12 and elevated GLI1 and PTCH1 transcript levels ...
Here, we demonstrate that the expression of essential HH pathway components like GLI1, PTCH1, and the HH ligands is highly diverse in CLL.
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#46Human Zinc finger protein GLI1 (GLI1) ELISA Kit - MyBioSource
Buy GLI1 elisa kit, Human Zinc finger protein GLI1 (GLI1) ELISA Kit-NP_001178839.1 (MBS7207170) product datasheet at MyBioSource, ELISA Kits.
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#47GLI1 and CTNNB1 Knockdown Activates NOTCH and mTOR ...
GLI1 and CTNNB1 Knockdown Activates NOTCH and mTOR Signalling in NB4 Myeloid Leukaemia Cells. YUKI OKUHASHI, MAI ITOH and SHUJI TOHDA. Anticancer Research ...
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#48Impaired Hedgehog-Gli1 Pathway Activity Underlies the ...
Impaired Hedgehog-Gli1 Pathway Activity Underlies the Vascular Phenotype of Polycystic Kidney Disease. Federico Franchi; ,; Karen M. Peterson; , ...
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#49Hedgehog Signaling - 第 117 頁 - Google 圖書結果
The clinical importance of GLI1 gene amplification is still unclear as early studies found low rates of GLI1 amplification ranging from 1.6% to 3.3% ...
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#50STAT3 induces the expression of GLI1 in chronic lymphocytic ...
However, what induces GLI1 expression in GLI1-unmutated CLL cells is unknown. Because signal transducer and activator of transcription 3 (STAT3) ...
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#51pLUT7 HA-GLI1 (Plasmid #62970) - Addgene
Plasmid pLUT7 HA-GLI1 from Dr. Michael Ruppert's lab contains the insert GLI1 and is published in J Cell Sci. 2015 Jan 27. pii: jcs.162164.
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#52GLI | Cancer Genetics Web - CancerIndex
Gene: GLI1; GLI family zinc finger 1. Aliases: GLI, PPD1, PAPA8. Location: 12q13.3. Summary: This gene encodes a member of the Kruppel family of zinc finger ...
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#53GLI1 Antibody (PCRP-GLI1-1A1) - DSHB
PCRP-GLI1-1A1 ... Antigen: GLI family zinc finger 1 Hybridoma Cells Available: Yes Antigen Species: Human Depositor: Common Fund – Protein Capture Reagents ...
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#54Nonclassical activation of gli1 as a therapeutic target for ...
Here, we investigate the role of the Hh pathway transcription factor, GLI1, in lung squamous cell carcinoma (SCC) and as a potential therapeutic target for ...
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#55Positive regulation of GLI1 by Hedgehog-GLI, TGFß-Smads ...
GLI1 transcription is upregulated in a variety of human tumors, such as basal cell carcinoma, lung cancer, breast cancer, gastric cancer, pancreatic cancer, and ...
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#56The Human Glioma-Associated Oncogene Homolog 1 (GLI1 ...
The Human Glioma-Associated Oncogene Homolog 1 (GLI1) Family of Transcription Factors in Gene Regulation and Diseases. Author(s): Hu Zhu and Hui-Wen Lo.
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#57Gli1 expression in human epiretinal membranes | IOVS
Thirty-three human ERM specimens were immunolabeled with anti-Gli1 antibody and the number of total cells/hyperfield (HF), Gli1 (+) cells/HF, and the percentage ...
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#58Gli1 activation and protection against hepatic encephalopathy ...
We measured Gli1 expression in brain tissues from mice and evaluated how circulating TGFβ1 and canonical hedgehog signalling regulate its ...
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#59Potential Target for Treating Many Cancers Found Within GLI1 ...
“We established in living human embryonic stem cells that removing the GLI1 regulatory region eliminated GLI1 expression and halted its activity ...
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#60Anti-GLI1 Antibody, Rabbit Polyclonal, 101156-T10 - Sino ...
Anti-GLI1 Rabbit Polyclonal Antibody (101156-T10), manufactured by Sino Biological is validated in IHC-P,ICC/IF. Custom antibody services and bulk ...
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#61Inhibition of prostate cancer proliferation by interference with ...
由 P Sanchez 著作 · 2004 · 被引用 625 次 — Blocking the pathway with cyclopamine or anti-SHH antibodies inhibits the proliferation of GLI1 + /PSA + primary prostate tumor cultures.
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#62Hedgehog/GLI1 signaling pathway regulates the resistance to ...
Moreover, the relationship between GLI1 and γ-H2AX (DNA damage protein) in cells treated with GLI1 siRNA and cisplatin was examined using western blot analysis.
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#63GLI1 is increased in ovarian endometriosis and regulates ...
The expression levels of GLI1, MMP2 and MMP9 was detected by qRT-PCR and western blot. The migration and invasion ability of human endometrial stromal cells was ...
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#64A Common Gene Variant in Hedgehog Pathway Gene Gli1 ...
In stage II patients, the homozygous GG variant of GLI1 rs2228226 remained significantly associated with decreased DFS in univariate (70 vs 145 months; HR 3.035 ...
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#65GLI / GLI1 - LSBio
LifeSpan BioSciences currently sells 112 antibodies , 2 peptides , 7 ELISA Kits , 8 proteins specific for GLI / GLI1.
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#66GLI-1 Antibody (NB600-600) - Novus Biologicals
Gli1 is a transcription factor involved in development, patterning and the regulation of cell fate-determination. A down-stream effector of the Hedgehog ...
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#67Probes for GLI1 | In Situ Hybridization, RNA-ISH | ACDBio
ACD can configure probes for the various manual and automated assays for GLI1 for RNAscope Assay, or for Basescope Assay compatible for your species of ...
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#68anti-GLI1 antibody (C-Term) | Product No. ABIN6971684
GLI1 (Glioma-associated oncogene 1) is a zinc finger transcription factor and oncogene. GLI1 is part of the hedgehog signaling pathway, but is also activated in ...
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#69DeSUMOylation of Gli1 by SENP1 Attenuates Sonic ...
The transcriptional output of the Sonic Hedgehog morphogenic pathway is orchestrated by three Krüppel family transcription factors, Gli1 to ...
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#70GLI1 | Gene - VarSome
GLI1 | Gene results | VarSome, the Human Genomics Community. ... The zinc finger transcription factor GLI1, which mediates Sonic hedgehog signaling during ...
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#71GLI1 and therapeutic opportunities in Ewing sarcoma ...
GLI1 is an upregulated direct target gene of EWS/FLI1 in Ewing sarcoma cells. Functional studies have demonstrated that GLI1 expression is relevant for the ...
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#72Glioma-Associated Oncogene 1 (GLI1) | SpringerLink
In vertebrates, the GLI gene family consists of GLI1, GLI2, and GLI3. The encoded GLI proteins have regions of high homology, but each protein ...
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#73GLI1 | Homo sapiens gene | Alliance of Genome Resources
Species: Homo sapiens; Symbol: GLI1; Name: GLI family zinc finger 1; Synonyms. GLI; GLI-Kruppel family member GLI1. Show All 9. Biotype: protein coding gene ...
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#74Gli1 - chemeurope.com
Gli1 glioma-associated oncogene homolog 1 (zinc finger protein) Identifiers Symbol GLI1 Alt. Symbols GLI Entrez 2735 HUGO 4317 OMIM 165220 RefSeq NM_005269.
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#75Neurooncology: Newer Developments - 第 391 頁 - Google 圖書結果
http://dx.doi.org/10.5772/63004 Therefore, suppression of SHH signaling through downregulation of Gli1 may serve as a venue of targeting SHH ...
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#76Back to the drawing board: Re-thinking the role of GLI1 in ...
GLI1 has been described as an oncogene in PDAC, making it a promising target for drug therapy. Surprisingly, clinical trials targeting HH/GLI1 ...
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#77Hirschsprung Disease and Activation of Hedgehog Signaling ...
Two different GLI1 mutations occurred in 2 HSCR patients; 1 patient had a mutation in GLI2, and the same GLI3 mutation occurred in 2 HSCR ...
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#78The Smoothened Receptor in Cancer and Regenerative Medicine
In this context, C3H10T1/2 cells exogenously transfected with vectors for Gli1 and a Gli-Luc reporter were used to evaluate selective inhibition of ...
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#79Issues in Hematology: 2011 Edition - Google 圖書結果
Gli1. regulates. the. proliferation. and. differentiation ... cell (HSC) and progenitor function in mice with a homozygous deletion of Gli1 (Gli1(null)).
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#81Tumor Suppressor Genes - 第 1 卷 - 第 90 頁 - Google 圖書結果
Gli1 was originally identified as a gene highly amplified in a glioblastoma ... and functional analyses have shown that Gli1 acts as a transcriptional ...
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#82A cell-based GEF assay reveals new substrates for DENN ...
Consistently, as monitored by the expression of the Gli1 transcription factor (48, 49), Hh signaling is repressed in the absence of DENND2B ...
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#83Toyota Corolla GLi Automatic 1.3 VVTi Cars for sale in Pakistan
Results 1 - 25 of 952 — There are 952 used Toyota Corolla GLi Automatic 1.3 VVTi starting at Rs. PKR 2180000. Find the largest number of verified ads for ...
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#84Scienza - Salute - Risultati da #688 - NextMe
... dove è stato effettuato lo studio, avrebbero individuato nell'aumento della molecola Gli1 la causa scatenante della malattia.
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#85FX
... scalable In particular, delta-like homologue 1 (DLK1) is co-expressed with Shh in the rat adrenal gland 163 and regulates Gli1 expression in vitro.
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#86SSML COLUMBUS ACADEMY DI ROMA: PRENOTA LA TUA ...
20 小時前 — ... GLI1 Glottodidattica infantile · La figura dell'insegnante di sostegno nella scuola · La professione docente nella scuola di oggi ...
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#87View bigwig file. json to have something like SamBuckberry ...
Default view showing a Group 3 enhancer at the GLI1 gene locus. bbi. It provides interactive visualization of sequences, annotation, multiple alignments, ...
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