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#1Fucosylation - Wikipedia
Fucosylation is the process of adding fucose sugar units to a molecule. It is a type of glycosylation. It is important clinically, and high levels of ...
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#2Fucosylation - an overview | ScienceDirect Topics
Fucosylation is the process of transferring fucose from GDP-fucose to their substrates, which includes certain proteins, N- and O-linked glycans in glycoprotein ...
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#3The Function of Fucosylation in Progression of Lung Cancer
Fucosylation, a type of glycosylation, has been studied frequently. It participates in the biosynthesis of blood H antigen and Lewis antigen ...
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#4Biological function of fucosylation in cancer biology - PubMed
由 E Miyoshi 著作 · 2008 · 被引用 414 次 — Fucosylation is one of the most common modifications involving oligosaccharides on glycoproteins or glycolipids. Fucosylation comprises the attachment of a ...
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#5Fucosylation in prokaryotes and eukaryotes | Glycobiology
由 B Ma 著作 · 2006 · 被引用 461 次 — In contrast, fucosylation appears less common in prokaryotic organisms and has been suggested to be involved in molecular mimicry, adhesion, colonization, and ...
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#6Machine Learning Classifies Core and Outer Fucosylation of ...
Core-fucosylation is a kind of N-linked glycosylation in which an alpha-1,6 linked fucose is added to the innermost N-acetylglucosamine (GlcNAc) ...
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#7Sialylation and fucosylation of epidermal growth factor ... - PNAS
Thus, increasing sialylation and fucosylation could attenuate EGFR-mediated invasion of lung cancer cells. However, incorporation of the core fucose by α1,6- ...
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#8from Cell Adhesion to Immune System Regulation and Diseases
Fucosylation is a biological process broadly observed in vertebrates, invertebrates, plants, bacteria, and fungi.
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#9Fucosylation and Cancer | SpringerLink
Fucosylation is one of the most common modifications involving oligosaccharides on glycoproteins or glycolipids. Fucosylation comprises the attachment of a ...
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#10Fucosylation Is a Promising Target for Cancer Diagnosis ...
Fucosylation is one of the most important oligosaccharide modifications involved in cancer and inflammation. Recent advances in glycomics have identified ...
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#11Cellular Fucosylation Inhibitors Based on Fluorinated ...
Abstract Fucosylation of glycans impacts a myriad of physiological and pathological processes. Inhibition of fucose expression emerges as a ...
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#12Mass spectrometric analysis of core fucosylation and ...
Electrospray mass spectrometry (ESI-MS) was used to measure the masses of an intact dimeric monoclonal antibody (Mab) and assess the fucosylation level.
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#13Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell ...
Although high core fucosylation catalyzed by fucosyltransferase 8 (Fut8) is a general feature of human milk glycoproteins, its role in the ...
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#14Integrated Strategy for Large-Scale Investigation on Protein ...
Core fucosylation (CF) is a special form of N-glycosylation and plays an important role in pathological and biological processes.
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#15Fluorinated Mannosides Inhibit Cellular Fucosylation.
Fucose sugars are expressed on mammalian cell membranes as part of glycoconjugates and mediates essential physiological processes.
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#16A prominent lack of IgG1-Fc fucosylation of platelet ...
Key Points. Antibodies causing FNAIT have decreased Fc fucosylation, unlike in refractory thrombocytopenia.Decreased Fc fucose increases affinity to ...
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#17Serum IgG Fucosylation in Advanced Endometriosis Diagnosis
The alterations in glycans fucosylation has been observed in variety of inflammatory conditions, among which there is rheumatoid arthritis (RA), ...
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#18FUT8 and Protein Core Fucosylation in Tumours - Journal of ...
FUT8 belongs to the fucosyltransferase family and is the key enzyme involved in N-glycan core fucosylation. FUT8 and/or core fucosylated proteins are frequently ...
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#19Glucose deprivation–induced aberrant FUT1-mediated ... - JCI
Here, we report a regulatory mechanism involving fucosylation by which glucose restriction promotes cancer stemness to drive drug resistance and tumor ...
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#20Deletion of Core Fucosylation on α3β1 Integrin Down ...
The role of core fucosylation in α3β1 integrin-mediated events has been studied by using Fut8 +/+ and Fut8 –/– embryonic fibroblasts, respectively ...
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#21Conditional control of selectin ligand expression and global ...
Glycoprotein fucosylation enables fringe-dependent modulation of signal transduction by Notch transmembrane receptors, contributes to selectin-dependent ...
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#22α(1,2)fucosylation in human colorectal carcinoma - Spandidos ...
To complete the study, the aberrant Lea/Lex α(1,2)fucosylation was determined in healthy and tumour colorectal tissues.
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#23Fucosylation and protein glycosylation create functional ... - eLife
Cholera intoxication of human colonic epithelial cells is dependent on recognition of protein glycosylation and fucosylation, ...
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#24FUT8 promotes breast cancer cell invasiveness by remodeling ...
Fucosylation is one of the most important types of glycosylation in cancer. Altered fucosylation has been implicated in malignant transformation ...
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#25Fucosylation Enhances the Efficacy of Adoptively Transferred ...
We hypothesized that fucosylation of antigen-specific CTLs in the setting of leukemia and breast cancer enhances their homing into tumor tissues and their ...
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#26Calreticulin activates β1 integrin via fucosylation by ...
FUT1 overexpression in CRT-RNAi cells resulted in increased levels of β1 integrin fucosylation and rescued cell adhesion to type-I collagen.
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#27High titers and low fucosylation of early human anti–SARS ...
Low fucosylation of anti-spike IgG was normalized in a few weeks after initial infection with SARS-CoV-2, indicating that the increased antibody-dependent ...
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#28Fucosylation of anti-dsDNA IgG1 correlates with disease ...
Cluster analysis showed that glycosylation of anti-dsDNA IgG and total IgG subclasses were different in SLE patients. Fucosylation, ...
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#29Methods for controlling fucosylation levels in proteins - Google
WO2015011660A1 - Methods for controlling fucosylation levels in proteins - Google Patents. Methods for controlling fucosylation levels in proteins Download ...
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#30Decreased Core-Fucosylation Contributes to Malignancy in ...
The object of the study is to identify N-glycan profiling changes associated with gastric cancer and explore the impact of core-fucosylation ...
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#31Fucosylation Analysis in Cetuximab & Human IgG N-glycans
Comparative analysis of fucosylation in cetuximab (monoclonal antibody) and human IgG (immunoglobulin G) N-glycans using GlycanExplorer ...
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#32Function and mechanism of O-fucosylation of malaria TSR ...
The aim of this project is to explore and characterize the O-fucosylation of TSR domains of critical P. falciparum molecules. As described across diverse ...
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#33Fucosylation and gastrointestinal cancer - Baishideng ...
Fucosylation, which comprises the transfer of a fucose residue to oligosaccharides and proteins, is regulated by many kinds of molecules, ...
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#34Fucosylation percentages following fucose titration in cell ...
Core fucosylation of an Fc N-linked glycan affects antibody effector functions, as the absence of fucose increases the antibody dependent cell cytotoxicity ...
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#35Fucosyltransferase 2 induces lung epithelial fucosylation and ...
Fut2 induces epithelial fucosylation and exacerbates airway inflammation in asthmatic patients in part through C3a production and monocyte- ...
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#36fucosylation - Wiktionary
EnglishEdit. EtymologyEdit · fucosyl + -ation. NounEdit. English Wikipedia has an article on: fucosylation · Wikipedia. fucosylation (plural fucosylations).
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#37fucosylation Gene Ontology Term (GO:0036065) - Mouse ...
Term: fucosylation. Definition: The covalent attachment of a fucosyl group to an acceptor molecule. Parent Terms: is-a glycosylation.
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#38Analysis of site and structure specific core fucosylation in liver ...
Keywords: Mass spectrometry; Data independent acquisition; GP-SWATH; Core fucosylation;. Soft fragmentation; N-glycopeptide; Cirrhosis.
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#39Core Fucosylation on T Cells, Required for Activation of T-Cell ...
fucosyltransferase (FUT8), as well as fucosylation- regulatory genes.7 Core fucose is a key glycosylation type in fucosylated a-fetoprotein, ...
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#40Cord Blood Fucosylation to Enhance Homing and Engraftment ...
Official Title: Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies. Actual Study Start Date : July 13, 2012.
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#41Fucosylation of a Therapeutic Antibody - BioProcess ...
Using a reporter gene ADCC assay, we monitored changes to antibody fucosylation and subsequently the antibody's ADCC activity.
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#42fucosylation - R&D Systems
Read fucosylation blogs from R&D Systems that feature the latest news, recent research, videos and more.
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#43Best 1 Definitions of Fucosylation - YourDictionary
Define fucosylation. Fucosylation as a noun means (biochemistry) Glycosylation using fucose moieties..
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#44PO-465 N-glycans of pseudomyxoma peritonei present highly ...
Finally, by using colon carcinoma cell line HCT116 with inherently defective fucosylation, we demonstrated that restoration of fucosylation enhanced GNAS ...
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#45Fucosylation definition and meaning | Collins English Dictionary
For example, fucosylation plays an important role in blood group determination, immunological reactions, and signal transduction pathways. Makoto Yoshida, Rishu ...
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#46Production of therapeutic antibodies with controlled fucosylation
Figure 1 Therapeutic antibody-induced ADCC in human blood. Therapeutic antibodies show the same antigen binding activity irrespective of core fucosylation of ...
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#47Studies on fucosylation in Trypanosoma brucei - Discovery ...
Fucose is a common sugar modification on eukaryotic glycan structures, but it has not been well described in trypanosomatids. To elucidate the role of fucose in ...
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#48An important role of l‐fucose biosynthesis and protein ...
results uncover a novel and broad role of L-fucose and protein fucosylation in plant immuinity. Key words: coronatine, fucosylation, ...
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#49from biochemistry to synthesis of core-fucosylated N-glycans
FUT8 is the enzyme responsible for all α1,6 core fucosylation in mammals. This enzyme catalyzes the transfer of an L-fucose residue from GDP-β-L ...
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#50Analyzing the Effects of O-Fucosylation on Secretion of ...
Antibodies: Anti-rabbit, Anti-mouse, Anti-human. Others: Glycosylation, Secretion, Folding, O-fucosylation, Thrombospondin type 1 repeat, ADAMTS proteins ...
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#51mAb Development Platforms - United BioPharma Inc.
United BioPharma's proprietary De-fucosylation technology has been established to reduce fucosylation of antibody by cellular engineering of parental CHO ...
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#52fucosylation | Semantic Scholar
The covalent attachment of a fucosyl group to an acceptor molecule. [CHEBI:62688, GOC:sart, PMID:19948734]
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#53fucosylation 中文 - 查查在線詞典
fucosylation 中文:巖藻糖椿鉑巖藻糖癥…，點擊查查權威綫上辭典詳細解釋fucosylation的中文翻譯，fucosylation的發音，音標，用法和例句等。
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#55Bacterial symbionts induce a FUT2-dependent fucosylated ...
This increase in fucosylation is accompanied by induction of fut2 mRNA expression and α1,2/3-fucosyltransferase activity. Colonization stimulates ERK and ...
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#56TWiV 700: 'Twas COVID and the aerosols - Microbe.TV
Otherwise, the observations on Ab fucosylation are intriguing. And today, as I gather, on the one-year anniversary of the initial report ...
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#57fucosylation 中文意思是什麼
巖藻糖椿鉑巖藻糖癥. fucosylation 例句. 目前還沒有fucosylation例句。 相似字; 英漢推薦; 漢英推薦. fucose · fucose dehydrogenase · fucose-1-phosphate.
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#58Search: authors:"Dong Yang" - Paperity
Fucosyltransferase 8 (FUT8) is the sole enzyme responsible for core fucosylation, and aberrant fucosylation by dysregulated expression of ...
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#59Encyclopedia of Cancer - 第 1166 頁 - Google 圖書結果
Futg b Fucosylation. Figure 1 Although these >Lewis antigens are fucosylated oligosaccharides, other glycosyltransferases except fucosyltransferases are ...
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#60Chemical Biology of Glycoproteins - 第 72 頁 - Google 圖書結果
Many proteins have been validated as carrying α-O-fucosylation, including plasminogen activator proteins,142 blood coagulation factors,37,143,144 Cripto,140 ...
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#61Biotechnology and Bioengineering - 第 153 頁 - Google 圖書結果
A production process in which the fucosylation levels of the products vary depending on the culture conditions would cause serious clinical complications ...
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#62An O-fucose site in the ligand binding domain inhibits Notch ...
Two glycosyltransferases that transfer sugars to EGF domains, OFUT1 and Fringe, regulate Notch signaling. However, sites of O-fucosylation ...
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#63Molecular Basis of Human Blood Group Antigens
Schematic drawing of interrelations between basic type 2 chains expressing li antigens, H(A, B) antigens created by fucosylation, and Sia-ll , -bl , -lb!
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#64What is meaning of fucose? - Movie Cultists
Fucosylation is one of the most important oligosaccharide modifications involved in cancer and inflammation. Recent advances in glycomics have identified ...
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#65Unexpected Receptor Functional Mimicry Elucidates ...
The intact glycopeptides were a variety of oligomannose, hybrid, and complex glycans, with or without sialylation and (core) fucosylation. Most of the observed ...
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#66ACE2-independent blood cell infection linked to severe COVID
Not much is known about fucosylation, in part because it is hard to study. Research antibodies cannot recognize the difference between a ...
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#67Covid antibody measurement units. 8% (meaning the test will ...
... and that their immune system developed antibodies to try to fight it off. investigated the role of antibody fucosylation in driving COVID-19 severity.
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