爸爸原本有肝腫瘤，後來醫生發現直腸附近有陰影，請爸爸做切片檢查

雖然醫生已經告訴我們是轉移，但醫生卻沒有告訴我們病理切片報告的內容

我們很想知道爸爸的詳細狀況，

想請問各位，爸爸的病理切片報告內容，謝謝各位！ 謝謝！

【檢查項目】
25003 Surgical pathology LevelIII *1件
25012 Immunohistochemical stains, eac *7件

【報告內容】
Soft tissue, perirectal region, CT-guided biopsy, carcinoma, metastatic

【描述】
The specimen submitted consists of three tissue fragments measuring up to
1x0.1x0.1cm. in size fixed in formalin.

Grossly, they are tan and elastic.
All for section. Jar 0

Microscopically, it show a picture of extensively tumor necrosis
with only a few viable malignant epitheloid tumor cells with pale
eosinophilic to clear cytoplasm, prominent nucleoil, and hyperchromatic
study reveals CK8(positive), Hep-Parl(focal positive, 5-10％),
CK7(negative), CD10(trade), CD20(negative), RCC(negative), and
vimentin(postive). According to clinical information, the metastatic
carcinoma is suggested and the metastatic hepatocellular carcinoma is
suggested first.

Reference：
1. Liver, right lobe, segments 5-6, segmentectomy, two locinon-encapsulated
grade 3-4/4 hepatocellular carcinoma (tumor up to 5.5cm in diameter)
composed of pleomorphic tumor cells arranged in predominantly
solid to focally sinusoidal trabecular growth patterns with patchy
sarcomatoid appearance, scattered bizarre giant tumor cells, multifocal
tumor necrosis, moderate mixed neutrophilic and lymphoplasmacytic
tumor-host reaction, three peritumoral satellite nodule formation near
smaller tumor, focal hepatic capsule invasion resulting in thickness and
fibrosis of surface capsule, focal intravascular tumor thrombus formation,
and no definite perineural invasiion identified.
2.Surgical margin, liver, right lobe, segment 5,6, segmentectomy, free of
tumor invasion (about 1.4cm. to the tumor).
3.Liver, tight lobe, segment 5,6, non-tumor part, segmentectomy, chronic
viral hepatitis B infection with scattered groundglass cytoplasmic change,
mild piecemeal necrosis, none lobular activity, mild to moderate
peri-portal inflammatory cells infiltration, numerious fibrous septa
formation with enlargement of portal tract, c/s histological activity
score=1/3 and fibrosing score=3/4 (according to the METAVIR system).
4.Gall bladder, cholecystectomy, cholelithiasis and chronic cholecystitis
with Rokitansky-Aschoff sinuses formation, and free of tumor.
5.Lymph node, near cystic duct, lymphadenectomy, negative for malignancy (0/1).
6. pTNM: T3N0Mx, stage IIIA (AJCC).

【檢查項目】
25006 Frozen section *1件
25012 Immunohistochemical stains, eac*3件
【報告內容】
Soft tissue, perirectal, frozen section and biopsy, consistent with
metastatic hepatocellular carcinoma
【描述】
Forzen section show scattered atypical cells with hyperchromatic
nuclei and extensive necrosis, in favr of carcinoma.
The specimen submitted for frozen section consists of one tissue
fragment measuring 0.5x0.1x0.1 cm in size in fresh state.

Grossly, it is grey and soft
All for section. Jar.0
Fs：frozen section A: frozen control

Microscopically, it shows scattered atypical cells with
hyperchromatic nuclei and extensive necrosis. Immunohistochemical study
show CK8(+), Hep-parl(+) and RCC(-), consistent with metastatic
hepatocellular carcinoma.


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