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#1STAT5A - Wikipedia
Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. ... STAT5A orthologs have been identified in ...
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#2STAT5A Gene - GeneCards | STA5A Protein
STAT5A (Signal Transducer And Activator Of Transcription 5A) is a Protein Coding gene. Diseases associated with STAT5A include Chronic ...
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#3STAT5A signal transducer and activator of transcription 5A ...
STAT5A positively regulates levels of DNMT3A, resulting in inactivation of tumor suppressor genes by epigenetic mechanisms in acute myeloid leukemia cells.
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#4STAT5a Protein - an overview | ScienceDirect Topics
The STAT5a and STAT5b proteins consist of an N-terminal domain that is involved in promoting STAT5 dimerization, a DNA-binding domain, an SH2 domain, a C- ...
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#5The role of Stat5a and Stat5b in signaling by IL-2 family ...
The activation of Stat5 proteins (Stat5a and Stat5b) is one of the earliest signaling events mediated by IL-2 family cytokines, allowing the ...
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#6Stat5a - Signal transducer and activator of transcription 5A
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth ...
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#7Stat5a/b are essential for normal lymphoid development and ...
Encoded by two separate genes, the two isoforms of this transcription factor, Stat5a and Stat5b, have distinct physiological functions (14). Deficiency of ...
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#8Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2 is a mouse monoclonal antibody for detection of phospho-STAT5A/B (Tyr694/699) also known as signal ...
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#9Interpretation of cytokine signaling through the transcription ...
STAT5A and STAT5B play essential redundant and nonredundant roles in orchestrating immunoregulation and the development of immune cells. · CD4 + CD25 + Tregs ...
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#10STAT5A protein expression summary
Gene name, STAT5A (HGNC Symbol). Synonyms, MGF, STAT5. Description, Signal transducer and activator of transcription 5A (HGNC Symbol). Chromosome, 17.
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#11Stat5a and Stat5b Proteins Have Essential and Nonessential ...
Similar types of ambiguities exist in establishing a role for the Stat5 proteins in responses to other cytokines. ... Stat5a is mandatory for adult mammary gland ...
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#12OMIM Entry - * 601511 - SIGNAL TRANSDUCER AND ...
601511 - SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5A; STAT5A - SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5; STAT5;; MAMMARY GLAND FACTOR; ...
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#13Anti-Stat5a Antibody (C-6): sc-271542 - Santa Cruz ...
Stat5a Antibody (C-6) is a mouse monoclonal IgM κ, cited in 8 publications, provided at 200 µg/ml · specific for an epitope mapping between amino acids 765-793 ...
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#14Recombinant Anti-STAT5a antibody [E289] (ab32043)
Rabbit recombinant monoclonal STAT5a antibody [E289]. Validated in WB, IP, IHC, ICC/IF, Flow Cyt (Intra) and tested in Mouse, Rat, Human.
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#15Phospho-STAT5A/B (Tyr694) Polyclonal Antibody - Thermo ...
Invitrogen Anti-Phospho-STAT5A/B (Tyr694) Polyclonal, Catalog # PA5-114648. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and ...
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#16Human Phospho-STAT5a/b (Y694/Y699) Antibody - R&D ...
View Human Phospho-STAT5a/b (Y694/Y699) Antibody (AF4190) datasheet.
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#17Stat5a (4H1) Mouse mAb#4807 - Cell Signaling Technology
Monoclonal Antibody for studying STAT5A. Cited in 1 publication. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously ...
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#18Human Gene STAT5A (ENST00000345506.8) from ...
Description: Homo sapiens signal transducer and activator of transcription 5A (STAT5A), transcript variant 2, mRNA. · RefSeq Summary (NM_003152): The protein ...
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#19MGI:103036 - signal transducer and activator of transcription 5A
View mouse Stat5a Chr11:100750177-100775995 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.
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#20STAT5A (human) - PhosphoSite
STAT5A Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other ...
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#21STAT5A antibody (13179-1-AP) | Proteintech
Cited in 10 publications. STAT5A antibody for FC, IHC, IP, WB,ELISA and reacts with human, mouse, rat.
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#22High activation of STAT5A drives peripheral T-cell lymphoma ...
STAT5A or STAT5B activation leads to a mature CD8+ T-cell disease in mice. To test whether hyperactive STAT5 signaling alone is sufficient to ...
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#23STAT5A - My Cancer Genome
Signal transducer and activator of transcription 5A (STAT5A) is a gene that encodes a protein that functions as a transcription activator.
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#24STAT5a/b Products | Bio-Techne
STAT5a /b Products. Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by ...
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#25Identification of STAT5A and STAT5B Target Genes in ... - PLOS
We applied chromatin immunoprecipitation followed by DNA sequencing using human CD4 + T cells to detect candidate genes regulated by STAT5A and/ ...
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#26stat5a - ZFIN Gene
Orthologous to human STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B).
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#27STAT5a Antibodies, cDNA Clones Research Reagents - Sino ...
STAT5A (Signal Transducer And Activator Of Transcription 5A) is a protein coding gene located on human chromosome 17q21.2. STAT5A is also known as MGF and ...
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#28Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W ...
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal culture supernatant, clone A11W, from rabbit; Synonyms: signal transducer and ...
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#29Biomarker: STAT5a/b (total) - BioAgilytix
Biological or Clinical Significance: Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which ...
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#30Src family kinases interfere with dimerization of STAT5A ...
In cytokine-induced STAT5 signaling, phosphorylation of STAT5A on Y694 leads to nuclear accumulation of the transcription factor, ...
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#31STAT5A Gene Set - Ma'ayan Laboratory - Computational ...
764 target genes of the STAT5A transcription factor in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated ...
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#32STAT5a Activation Mediates the Epithelial to Mesenchymal ...
Thus, RhoA regulates Stat5a via tyrosine phosphorylation and via a yet to be ... Two separately encoded Stat5 transcription factors, Stat5a and Stat5b, ...
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#33STAT5A Rabbit pAb-Polyclonal Antibodies - ABclonal
Rabbit STAT5A Rabbit pAb (A7733), validaed in WB,, IF and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for target ...
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#34Genetic polymorphism of STAT5A protein: relationships with ...
Genetic polymorphism of STAT5A protein: relationships with production traits and milk composition in Italian Brown cattle - Volume 76 Issue 4.
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#35STAT5A mouse monoclonal antibody, clone OTI9F7 ... - OriGene
Full length human recombinant protein of human STAT5A (NP_003143) produced in HEK293T cell. Formulation, PBS (pH 7.3) containing 1% BSA, 50% glycerol.
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#36STAT5a Confers Doxorubicin Resistance to Breast Cancer by ...
Here we identified STAT5a as a chemoresistance inducer that regulates the expression of ABCB1 in breast cancer and can be targeted by pimozide, ...
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#37STAT5A | Cancer Genetics Web - CancerIndex
Gene: STAT5A; signal transducer and activator of transcription 5A. Aliases: MGF, STAT5. Location: 17q21.2.
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#38Stat5a (signal transducer and activator of transcription 5A)
Symbol: Stat5a. Name: signal transducer and activator of transcription 5A. RGD ID: 3773. Description: Enables DNA-binding transcription factor activity; ...
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#39Asymmetrically Substituted m‐Terphenyl Phosphates Inhibit ...
Abstract We recently presented Stafia-1 as the first chemical entity that inhibits the transcription factor STAT5a with selectivity over the ...
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#40STAT5A and STAT5B—Twins with Different Personalities in ...
Enhanced STAT5A/B activation is achieved by copy number gains, enhanced protein expression, or gain-of-function (GOF) mutations, leading to higher pYSTAT5A/B ...
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#41Stat5a Serine Phosphorylation - Journal of Biological Chemistry
We have previously shown that in HC11 mammary epithelial cells Stat5a is phosphorylated on Tyr 694 in a prolactin-sensitive manner, whereas ...
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#42Characterization of Stat5a and Stat5b Homodimers and ...
Lactogenic hormone treatment of HC11 mammary cells resulted in tyrosine phosphorylation of Stat5a and Stat5b, dimerization, and rapid nuclear ...
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#43STAT5A/B phospho Tyr694/Tyr699 antibody (pAb) - Active Motif
STAT5A /B phospho Tyr694/Tyr699 (STAT5A/B P-Y694/699) antibody for use in Western blotting.
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#44anti-STAT5A antibody :: Mouse Stat5 (Tyr-694) Monoclonal ...
Buy anti-STAT5A antibody, Mouse Stat5 (Tyr-694) Monoclonal Antibody-NP_003143.2 (MBS470030) product datasheet at MyBioSource, Primary Antibodies.
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#45Serine Phosphorylation of GH-Activated Signal Transducer ...
Unexpectedly, STAT5a-Ser 725,779 Ala and STAT5b-Ser 730 Ala displayed approximately 2-fold higher GH- or PRL-stimulated transcriptional activity compared with wild- ...
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#46STAT5A-Deficient Mice Demonstrate a Defect in Granulocyte ...
STAT5A -Deficient Mice Demonstrate a Defect in Granulocyte-Macrophage Colony-Stimulating Factor–Induced Proliferation and Gene Expression. Gerald M. Feldman,.
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#47PrEST Antigen STAT5A (APrEST89109) - Atlas Antibodies
PrEST Antigen STAT5A antigen APrEST89109 for signal transducer and activator of transcription 5A.
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#48STAT5a/b Antibody [Unconjugated] - Pan Specific (AF2168)
Cited in 14 publications. View Rabbit Polyclonal anti-STAT5a/b Antibody [Unconjugated] - Pan Specific (AF2168). Validated Applications: WB, Simple Western, ...
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#49Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody | 06-867
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody is a rabbit polyclonal antibody for detection of phospho-STAT5A/B (Ser726/Ser731) also known as signal ...
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#50STAT5A Antibody | Abbexa Ltd
Signal Transducer And Activator of Transcription 5A (STAT5A) Antibody. Catalogue No: abx036657. Price: £270.00. (Size: 100 µg). Reviews: 0 reviews
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#51Interplay between SMAD2 and STAT5A is a critical ...
Our model analysis points to the transcription factors NFAT2A, STAT5A and SMAD2 as key regulators of the differential expression of IL-17A ...
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#52STAT5A - LSBio
STAT5A. signal transducer and activator of transcription 5A. STAT5A is a member of the STAT family of transcription factors.
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#53STAT5A/B Blockade Sensitizes Prostate Cancer to Radiation ...
For HR DNA repair, Stat5a/b regulation of Rad51 and the mechanisms underlying the regulation were investigated in prostate cancer cells, ...
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#54PIKE‐A is required for prolactin‐mediated STAT5a activation ...
Here, we show that PIKE-A directly associates with both signal transducer and activator of transcription 5a (STAT5a) and prolactin (PRL) receptor, ...
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#55Signal transducer and activator of transcription 5 (STAT5 ...
In mammals, STAT5 is unique because it is encoded by two genes, termed Stat5a and Stat5b, derived from a relatively recent duplication event ( ...
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#56STAT5A (NM_003152) ORF cDNA clone | Expression-ready
STAT5A cloned gene : ORF from ATG to Stop, in pUNO1 expression plasmid selectable in E.coli and mammalian cells. Fully sequenced.
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#57STAT signaling in ischemic heart: a role of STAT5A in ...
A rapid activation of JAK and several STATs, including STAT3, STAT5A, and STAT6 also occurred during myocardial ischemia and reperfusion.
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#58Stat5a - MMRRC
Stat5a Gene Details Email me when MMRRC products with Gene Stat5a become available ; Name, signal transducer and activator of transcription 5A ; Synonyms, STAT5.
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#59(PDF) STAT5A and STAT5B—Twins with Different ...
PDF | The transcription factors STAT5A and STAT5B have essential roles in survival and proliferation of hematopoietic cells—which have been ...
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#60pAD-CMV-STAT5A-CA-CMV-GFP (Plasmid #83255) - Addgene
Gene/Insert name. Stat5a · Alt name. signal transducer and activator of transcription 5A · Species. M. musculus (mouse) · Mutation. constitutively active · Entrez ...
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#61Stat5b (Signal Transducer and Activator of Transcription 5b ...
Unlike mice, STAT5a sufficiency in humans cannot compensate for STAT5b defects. Our study aims to determine the relative contributions of STAT5a and STAT5b ...
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#62KEGG T01001: 6776
STAT5A, MGF, STAT5. Name. (RefSeq) signal transducer and activator of transcription 5A ... 6776 (STAT5A) 04630 JAK-STAT signaling pathway 6776 (STAT5A)
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#63STAT5A (Homo sapiens) - encode
STAT5A (Homo sapiens). { ; }. Target name: STAT5A. Target gene ID. GeneID:6776. Target gene symbol. STAT5A. External resources. FactorBook:STAT5A ...
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#641Y1U: Structure of unphosphorylated STAT5a - RCSB PDB
Structure of unphosphorylated STAT5a. PDB DOI: 10.2210/pdb1Y1U/pdb. Classification: SIGNALING PROTEIN; Organism(s): Mus musculus; Expression System: ...
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#65STAT5A(phospho S726) & STAT5A Protein Phosphorylation ...
This protein phosphorylation antibody pair set comes with two antibodies, one against the STAT5A protein, and the other against the specific S726 ...
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#66Anti STAT5A Antibody | Bio-Rad
Rabbit anti STAT5A antibody recognizes signal transducer and activator of transcription 5A (STAT5A), a member of the STAT protein family.
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#67STAT5A - wikidoc
STAT5a shares the same six functional domains as the other members of the STAT family. It contains 20 amino acids unique to its C-terminal domain and is 96% ...
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#68STAT5A | gnomAD v2.1.1 (non-TOPMed) | gnomAD
Constraint is based on the full gnomAD dataset, not the selected subset. Category, Expected SNVs, Observed SNVs, Constraint metrics. Synonymous ...
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#69STAT5A reprograms fatty acid metabolism and promotes ...
STAT5A, FABP5, Fatty acid metabolism, Tumorigen- esis, Gastric cancer. Introduction. Although in recent years its global incidence.
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#70Signal transducer and activator of transcription 5A/B in ...
In prostate cancer, the components of the JAK2-STAT5A/B signaling pathway provide molecular targets for small-molecule inhibition of ...
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#71STAT5A | Homo sapiens gene | Alliance of Genome Resources
Species: Homo sapiens; Symbol: STAT5A; Name: signal transducer and activator of transcription 5A; Synonyms. MGF; STAT5. Biotype: protein coding gene ...
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#72Stat5a/b in Prostate Cancer Metastasis - The American Journal of ...
The 94-kDa Stat5a and 92-kDa Stat5b are highly homologous isoforms that are critical cytoplasmic signaling proteins and nuclear transcriptional factors.
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#73Stat5a - Labome.Org
..We have now investigated the role of Stat5 proteins in this process. Whereas Stat5a and Stat5b KO mice have decreased numbers of CD8+ T cells, Stat5- ...
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#74PFKFB4 promotes angiogenesis via IL-6/STAT5A/P-STAT5 ...
PFKFB4 promotes angiogenesis via IL-6/STAT5A/P-STAT5 signaling in breast cancer. Dan Li 1#, Jiaping Tang 1#, Ruifang Gao 1,2#, Jinxin Lan 1 ...
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#75STAT5a Antibody, anti-human, REAfinity™ | Recombinant ...
Clone REA549 recognizes the human STAT5a antigen, a member of signal transducers and activators of the transcription (STAT) family.
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#76Disruption of STAT5A and NMI signaling axis leads to ISG20-driven ...
STAT5A is essential for differentiation of secretory mammary alveolar epithelium. Active STAT5A characterizes breast cancer patients for favorable prognosis ...
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#77Stat5a Mouse Gene Details | signal transducer and activator of ...
Phenotype data for mouse gene Stat5a. Discover Stat5a's significant phenotypes, expression, images, histopathology and more. Data for gene Stat5a is all ...
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