"While the exams are important and they are a major milestone, please remember that whatever grades you receive, they do not define your life, your character or you as a person in the slightest. You are worth so much more than the piece of certificate you are going to take home and I hope you know that. Values such as honesty, kindness, independence, creativity, reliability and perseverance are the things that I see in you but will not be written on the paper, which is why I need to tell you so that you will know how amazing you are. You are an incredible gift that we treasure so deeply and you've lit up our world since you came into it."

Here's sharing heartfelt letter I wrote to my firstborn who will be taking her PSLE exams in three days' time. You've got this, dear Angel!

HDD約3万5000台を運用した実績からSeagate製品の圧倒的壊れっぷりが明らかに(2014)
https://gigazine.net/news/20140924-hdd-reliability-sep2014/

6562 聯亞藥

中央流行疫情指揮中心於8月16日宣布聯亞生技UB-612疫苗未取得緊急使用授權（EUA），對此結果聯亞生技深感遺憾，並於此做出以下聲明：

聯亞非常感謝4215位參加聯亞UB-612次單位疫苗的第一期和第二期臨床試驗的受試者，謝謝受試者慷慨地貢獻出自己的手臂，數月來孜孜不倦地填寫電子日誌及嚴重危險不良反應監測。這個二期試驗期中結果顯示相當成功。聯亞董事長王長怡以最誠懇負責任的態度向所有受試者表達參加的疫苗成效三項重要數據：

(1)解盲最主要觀察的安全性指標、除了與疫苗接種部位相關的肌肉疼痛、紅腫及皮膚過敏等輕度不良反應外、其他全身性不良反應均與對照組(placebo)相近。UB-612次單位疫苗是注重自病毒欲感染細胞那一瞬間開始至其後將被重要的免疫細胞辨識而發揮抵禦功能的每一環節，全依層層免疫原理來確保參與者的健康，所以是一以病毒免疫為基石的嶄新疫苗；雖開發產品穩定生產的功夫及時程比mRNA及腺病毒載體(adenovector)疫苗更多，但回報的安全性也相對為高；
(2)在抗體反應上有超過95%18-65歲的成年組受試者和將近90%的?65歲老年組受試者對新冠病毒武漢株(WuhanSARS-CoV-2virusstrain)的中和抗體和對病毒想進入細胞而與細胞受體結合處(receptorbindingdomain,RBD)的首要敲門磚[第一棘蛋白(Spike1,S1)之抗體]，即Anti-S1-RBD抗體的血清反轉率可達到四倍上升；中和抗體濃度的幾何平均效價也高於感染後恢復期血清的中和抗體濃度，和第一期臨床試驗的結果相當一致，且具高度重覆性與可靠性(reliability)；
(3)更重要的是聯亞生技的UB-612疫苗也激發疫苗保護力中另一極為重要的「T細胞免疫力」。這些數據均顯示此UB-612具備成為安全有效對抗新冠肺炎疫苗的優質特色。

政府採用「僅取單一時間點」的免疫橋接方法，「以AZ疫苗產生的對抗新冠病毒原型株之中和抗體力價」作為最重要且唯一比對標準，否決了聯亞UB-612的緊急授權申請。這樣的審查標準只是局部性免疫，無法全面評估疫苗激發出來的免疫力及其面對未來防疫的實效，尤其T細胞免疫力在近十年愈來愈受國際免疫學者重視，因其不但有毒殺細胞內病毒的功效，也協助更重要的免疫持久性(immunitypersistence)，讓接種者不要耽心接種3-6個月後免疫力驟降而難以抵禦更頑強的病毒。至於免疫橋接，聯亞認為中和抗體力價不應只觀察單一時間點，而更應該注重抗體力價的維持性(maintenance)及對抗目前流行病毒變異株的效力；同時也要納入T細胞免疫反應分析，才能較完整的評估疫苗的綜合效力，也給國人更專業的病毒免疫全貌科學數據。

UB-612疫苗為強化T細胞免疫多位點胜月太(multi-epitopepeptide-basedvaccine及S1-RBD蛋白的B細胞免疫特別設計多重免疫擋火牆組合而成的次單位疫苗(subunitvaccine)。在美國執行的猴子攻毒試驗證實可降低病毒量至無法偵測的極限值以下。經第一、二期臨床證實可有效誘導「T細胞毒殺病毒的免疫力」以及產生「阻擋病毒和細胞表面的ACE2受體結合的RBD蛋白部位」之中和性抗體，因此能高效阻斷病毒感染寄主細胞。UB-612疫苗的三大優勢是:
(1)產生的中和性抗體不但持久(半衰期195天)；
(2)可以中和大多數病毒變異株，尤其對印度Delta變異株仍保有與原始武漢株（WT）相近之中和抗體效價。較目前上市的疫苗(包括AZ疫苗)所產生的中和性抗體，對印度Delta病毒卻均大幅下降更是接種者的福音。
(3)UB-612疫苗能精準的產生有效T細胞免疫力是第三個極大優勢。目前關於T細胞免疫力的重要性，國際探討免疫橋接的論文，都把「疫苗接種後」的血清抗體濃度和細胞免疫反應，去和「康復者」血清及血樣相比。例如:AZ產生的抗體雖然只達到康復者血清的兩成，就認為有保護力；將T細胞納入考量後，AZ抗體只需達到康復者血清的3%就認為有保護力。即中和抗體濃度並不是保護力必要或唯一的因素。

政府於6月10日公布的EUA審查是以單一側重中和性抗體的免疫橋接為標準，聯亞也體諒政府事先無法藉由良好橋接試驗規劃，取得打AZ疫苗者的血清及血液細胞樣本，因此無法納入T細胞免疫力及其他的評量，只能以部桃醫院接受過AZ疫苗的醫護有限血清樣本以單一時間點，評估對抗新冠病毒原型株之中和抗體力價結果作為免疫橋接標準，但這對UB-612這款以短月太及小片段蛋白，目的用來避掉大部分疫苗的副作用，卻又能產生T細胞與B細胞均衡且專一的免疫性，UB-612疫苗的設計是全球獨一的，惜未事先經過充分討論或溝通，且匆忙制定的標準下，UB-612疫苗無法通過EUA審查，可能讓一支可以對抗現在正在國際間流行的變異病毒且優秀的疫苗錯失保護國人及人類健康的良機。

聯亞團隊除了感謝受試者外，也要感謝執行試驗的醫院、IRB及試驗主持人。感謝所有試驗中心的臨床團隊至今仍與聯亞一起努力。聯亞誠摯呼籲受試者對聯亞有信心，協助完成聯亞疫苗二期臨床試驗六個月的訪視，向法規單位證明UB-612產生的抗體有強而有力的續航力！聯亞也會提供受試者最完整的抗體群組輪廓來回報受試者。聯亞非常感謝CDE的傾力輔導，沒有CDE，就沒有UB-612。還有最後一哩路！目前持續與CDE、食藥署及有關專家進行溝通，討論“全面免疫力評估及納入目前流行之Delta等變異株病毒進行中和抗體效力的比較性試驗”，以完整呈現聯亞生技UB-612疫苗設計的優異性：人體免疫系統除了產生B細胞抗體反應之外，也產生能對抗病毒變異株的T細胞免疫反應。尤其所產生的抗體具中和Delta等變異株病毒的有效性。聯亞取得國際認證的決心不變，這是聯亞的使命，希望一起攜手合作，守護台灣，守護全球防疫。

► Có thể các bạn thấy lạ, căn bản là mình cũng thấy lạ luôn, đó là trên thị trường mới xuất hiệu một thương hiệu sản xuất bộ nhớ máy tính hoàn toàn mới mang tên TRM (Viết tắt của Trust, Reliability và Mobility) đến từ Singapore. Không chỉ có SSD SATA, M.2 mà còn có cả RAM cho Desktop, Laptop và USB lẫn thẻ nhớ. Hãy cùng mình tìm hiểu xem thương hiệu TRM này có những sản phẩm hay ho ra sao nhé.
►Tham khảo thêm link của nhà phân phối TRM chính thức: https://xtrend.vn/ssd-bo-nho-trong/
Cả nhà theo dõi thông tin của mình tại đây:
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© Copyrighted by SH MEDIA ☞ Do not Reup

ชอบไหม? เปิดตัวแล้ว The new 2021 Nissan Navara / Frontier (นิสสัน นาวาร่า / ฟรอนเทียรฺ) รุ่นปรับโฉมใหม่ พร้อมรุ่นพิเศษ Pro4X เริ่มจำหน่ายในไทย ธันวาคม 2020 นี้

YOKOHAMA, Japan – Nissan today unveiled the new Nissan Navara pickup*, that delivers an enhanced level of safety, comfort and driving pleasure, while continuing to bring durability, reliability and versatility.

The pickup, known as the Nissan Frontier in Mexico and South America, marks another milestone in the company’s Nissan NEXT transformation plan.

Over the many decades since the first Nissan pickup hit the road, the Nissan Navara has continued to accompany and empower customers in many facets of their lives.

Building on more than 80 years of Nissan pickup heritage, it stays true to the company’s belief in bringing advanced technologies to as many customers as possible.

A reliable partner for work or travel, the new Nissan Navara comes with many best-in-class technologies, including an array of Nissan Intelligent Mobility features and safety systems, making it the most advanced Navara yet.

“We packaged the new model with a full set of advanced technologies to ensure enhanced dynamic performance on- and off-road, as well as safety and comfort ushering in a new age of toughness, tech, and peace of mind,” said Ashwani Gupta, Nissan’s chief operating officer. “For our customers it means confidence, driving pleasure, practicality and pride of ownership.”

Among the Nissan Intelligent Mobility features that will be available across the global Navara and Frontier lineup is Intelligent Forward Collision Warning, which monitors the second vehicle ahead as well as the vehicle directly in front to reduce the risk of multi-car accidents. Intelligent Emergency Braking activates the brakes to avoid collisions, reducing the stress of driving in traffic or on busy streets.

Intelligent Around View Monitor uses four cameras to help drivers notice people and cars surrounding and approaching the vehicle, making it easier to parallel park or to position the vehicle when hitching to a trailer. New to the system is an off-road monitor, which checks surrounding obstacles at low speeds when in four-wheel drive mode.

The new model features* a strengthened rear axle, increased payload capacity, additional truck bed volume and a new integrated step in the rear bumper for easier access to the truck bed. A new steering rack has been adopted to enhance maneuverability at low speeds and steering response across the speed range.

It offers a quiet and comfortable ride thanks to significant decrease of vibration and improved noise isolation.

These new features make the vehicle the ultimate travel and worksite partner, prepared to take on new challenges while still offering optimal room, comfort, safety and ease of work.

The new model features an “unbreakable” design language. It introduces a new ruggedly bold, stylish exterior made for extreme elements.

“The new Navara has a very recognizable look, but it’s now more imposing thanks to its high command structure, new interlocking frame grille and new high-tech, squared C-shaped headlamps,” said Ken Lee, Nissan’s senior design director for pickups and frame SUVs.

or the first time for the Navara and Frontier, Nissan will offer the PRO-4X grade, a style package aimed at adventure lovers and travelers craving an escape from their daily routine. The PRO-4X grade comes with its own athletic look, with a black emblem, orange-accented front bumper, black grille, door handles, roof racks and running boards accented by 17-inch black wheels and all-terrain tires.

The new pickup goes on sale in December in Thailand, with other markets to follow later.

插入之教室???

DW二穴雙出CNC鋁合金氣咀 -售價HK$380一對(一角工房發售)
Y-SHAPED CNC VALVE STEM
備有紅、粉紅、金、藍、綠、銀、鈦、黑等8色可供選擇
http://moto-one.com.hk/Products.php?id=8263

有冇試過去打胎氣時
碌嚟碌去都唔就手？

有冇試過裝左胎壓錶後
去打氣冇工具扭開？

DW二穴雙出氣咀幫到你

胎壓錶工作中仍可打氣
有兩個穴比你
多個窿，更歡樂

Y字型設計
不同姿勢，任你發揮

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2 valve stems allow easier filling and easier access tire pressure sensor
The tubeless valves can prevent unsafe factors effectively which caused by auto vacuum valves puncture rollover.
Easy for DIY installation,Directly bolt on
Placement on motorbike:Front, Rear
Anodiced color coating to keep products looking great for years to come

Stem Material: Aluminium
Cap Material: Aluminium
Stem Angle: 180 & 15 Degree
Valve Core: Standard short valve core
Weight: 17 Grams Each
Applicable Rim Hole: 11.3mm/8mm
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香港總代理：
一角工房有限公司
零售及批發可聯絡

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讓我們以更充裕時間提供優質服務

零售，訂件 Thomas:
https://wa.me/85295659995

維修Whatsapp:
https://wa.me/85255485044

一角工房有限公司
TENCENTS MOTORCYCLE WORKSHOP LIMITED
G/F, No.28, YIN ON ST., TO KWA WAN, KLN.
土瓜灣燕安街28號地下
Tel: +852-55485044
Email: tencentsmotorcycle@gmail.com
Office hour : Mon to Sat 10:00-20:00