The bureau recommended in its paper to allow the Privacy Commissioner for Personal Data to apply for court injunctions to preempt “large-scale or repeated” doxxing acts targeting specific groups or individuals.

Read more: https://bit.ly/3tJMKRP

當局更擬設「預防」機制，建議賦予私隱專員權力，在認為社會上已出現，或很大機會出現大規模或重複違反《私隱條例》情況，可向法庭申請禁制令，預防「起底」事件發生。
____________
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#兇手不只一個

阿茲海默症惡化😰？中研院找到 #蛋白質幫兇！

👵👴👵👴
　　
#阿茲海默症 是最常見的 #老年失智症。過去，科學認為阿茲海默症起因於：🧠大腦中的2種蛋白質錯誤堆疊：
　　
1⃣：蛋白質Aβ（Amyloid-β）
2⃣：Tau蛋白（Tau Protein）
　　　
最近，中研院基因體研究中心 #陳韻如研究團隊 證實，導致阿茲海默症病情惡化，還有另一個💢蛋白質幫凶：
　　
3⃣：蛋白質TDP-43
　　
👉本研究證實：大腦 #蛋白質TDP-43 錯誤表現後，會與 #Aβ 作用，產生更有毒的中間產物，造成阿茲海默症病情惡化！
　　
👩‍🔬陳韻如表示，「我們發現TDP-43在阿茲海默症裡扮演多重的角色：一方面會直接與Aβ反應誘發Aβ寡聚體形成，造成 #神經突觸功能障礙，以及記憶受損；另一方面TDP-43也會增加 #腦部發炎反應，讓患者對於空間的記憶能力降低。」
　　
🌎全球約5,000萬名失智症患者中，有將近六、七成都是阿茲海默症病人。發病後會 #記憶力下降、#喪失語言功能、#空間感退化 #常迷路，造成自己及親友的生活負擔。但目前還沒有有效的治療藥物。
　　
📍本研究有助於掌握更多阿茲海默症的發病特徵及機制，未來，可望透過TDP-43，為神經退化疾病尋找🔍診斷及💊治療的新方法！
　　
📍本研究起始於兩位博士後研究學者施耀翔與杜玲嫻博士，並由張婷宇碩士加入團隊協力完成。研究成果已於今（2020）年11月23日發表於《#自然通訊》（Nature Communications）。

—
Curbing #TDP-43 May Ease the #Alzheimer’s Disease Progression
　　
Neurodegenerative diseases are making more impacts socially and economically as human life expectancy gets higher and higher. The scientific world still doesn’t have many clues regarding these diseases. Dr. Yun-Ru (Ruby) Chen’s research has been circled around the protein TDP-43 and its role in several neuro-degenerative diseases, in a paper published in the journal Nature Communications, they have reported a new insight into how TDP-43 is affecting Alzheimer’s disease.
　　
The team designed and made several antibodies, they will look into a solution in finding a best antibody that can do a preempt act to interact with TDP-43. If less inflammation can be managed, less memory loss of AD patients could be feasible. A synergistic effect to disrupt TDP-43 and Aβ interaction may also ameliorate AD.

—
📍新聞稿：https://www.sinica.edu.tw/ch/news/6721
📍Press Release: https://www.sinica.edu.tw/en/news/6721
📍論文全文：https://www.nature.com/articles/s41467-020-19786-7

—
#中研院基因體研究中心
#陳韻如副研究員
#神經退化疾病

(English writing below)

上星期天，我到一間小花圃做春節直播。

以我的慣例，我如果用到店家的地方，我都會買些東西，不佔他人做生意的便宜。

那天開直播前，本想通知店員一聲，但因為急著在一個時間點前結束，忘得一乾二淨，就有勞我師兄去物色購買適合的盆景。

當時有三位員工 - 兩位華族女子，一位異族外勞男子。

開播到一半時，男員工看到我先生的手機正播映著我的直播。

「哇！這是現場直播嗎？」他很興奮地問我先生，「在哪裡可以看？」

「你可以在臉書看。」

男員工二話不說，拿出手機，開啟臉書應用程序，請我先生為他找出我的臉書。先生輸入我的名字後，接下來就更好笑了。

我當時毫不知情，因為專注在直播。

結束後，我翻看按讚名單時，還想著怎麼會有異族朋友的名字。後來，先生才告訴我事情的來龍去脈。

昨天在剪輯直播，想這星期上傳到Youtube時，才發現那位男員工還向我鏡頭揮手，並展示播放著我直播的手機螢幕。😂

雖然我全程都說著華語，但想必他應該或多或少都聽得懂吧！

這畫面非常有趣，因為幾天前，一位女讀者來訊詢問我批八字的收費。（我服務的收費都列在：www.qianyu.sg/consultations 有中文網頁功能）

這女讀者說，我影片裡的資訊非常準確及珍貴。

我感謝她告訴我，因為我沒有印象在臉書互動裡看過她的名字。

她說她害羞。

這讓我想起另一位女客人，也曾說過類似的話。她說她一向很低調，所以雖然獲益匪淺，但從沒想過要按讚。

我問她：

萬一我寫了那麼多，卻得不到觀眾按讚的肯定，以致我放棄寫作與拍片呢？

她沒回答我。

我笑說，我雖不會因此而放棄，因為我曾經發過願，我也會用我的一生去履行我的發願。

但是，只拿不給，非君子所為，而是自私自利。 我也是人，自然也會需要認同感，尤其是寫的又是一些較另類的課題。

給予鼓勵是一種善行，也是一種感謝，無論是通過按讚、留言、分享，或告訴我。

直接與我貼文互動的好處是有時，可以利益其他比我們更需要這訊息的人。

打從我在去年六月底每星期更新Youtube影片後，我收到的詢問也多了。這些詢問當中，好一些是因為他們的臉書朋友分享了我的影片，而認識我。

他們的臉書朋友並不知道他們來找我服務。

畢竟，我們不會向全世界公佈我們的貼身問題。很多時候，向一個陌生人傾述你的問題，比向朋友訴苦還有用，因為那位陌生人有解決你問題的能力。

我在網路寫作已有三年半的時間，看過數百人。表面上看來是我在幫助人，但如大聖佛陀所言，眾生讓我們實踐自己的修行，幫助我們開悟成佛的人。

這是個互相利益的循環。

見的人越多，我越覺得娑婆世界如浮雲，終究沒有任何人事物是自己的。

寫作拍片越多，自己的思維與志向越明確。

我看到到因果的可怕，不想要我客人那般的命運，因此我更加謹言慎行。我親眼目睹貪、嗔、痴如何能毀掉一個人的人生，所以我打開自己的心房，學習把大愛放送出去，放下不利益他人的固執想法。

因此，感謝妳、你、您幫助我成為一個更好的人，幫我找到我的人生目標。這輩子，我從來沒有做一件事那麼開心過，我也想要一生就這樣做下去。

希望我也能幫助到你，盼你也能幫到別人。

___________________________

So last Sunday, I went to a plant stall to do a CNY Live.

As per my usual practice, I would always buy something from the shop if I use its premises. I don’t take advantage of other people’s businesses.

That day, I wanted to preempt the plant stall staff but in my haste to start my Live, I plain forgot about it. So the husband went about looking for a plant to buy on my behalf.

There were about three staff - two ladies and the gentleman standing behind me in this photo.

Halfway through my Live, the male staff saw the handphone screen of the Husband’s.

“Wah! It’s Live ah?” He excitedly asked the husband. “How to see?!”

“You can see on Facebook!”

The staff whipped out his mobile phone and opened the Facebook app. Then the husband typed in my profile name and what followed next was comical.

I wasn’t aware as I was very focused on presenting to my Live audience.

After the Live ended, I looked through the list of Likes to see who engaged with my video.

And I was wondering why there were some foreign names.

Then the husband told me what transpired.

Yesterday while editing the Live for my Youtube upload this week, I realised at one point in time, the staff also waved to my camera and flashed his handphone screen of my Live. 😂

I bet he somewhat understood what I said, despite it being in Mandarin.

It was an interesting moment because few days ago, a lady PM me to inquire about my Bazi consultation fee. (It’s all listed at www.qianyu.sg/consultations btw)

She told me the information in my videos were accurate and valuable.

I thanked her for telling me because I had never seen her name appeared in my engagement list.

She told me she was shy.

This reminded me of a Bazi client who told me the same thing. That client said she had always been low profile, so she did not think to Like my posts even though she benefitted from it.

I told the client:

But what if I stopped writing and filming because I received no or little affirmation from the audience?

She didn’t answered me.

I laughed and said I would not stop because I had made an aspiration in the past. I had made it my lifetime goal to keep my words.

But to be only taking and not giving is always selfish. I am human. And humans always need to feel belonged in one way or another. Even more so when I am writing about unorthodox topics.

Giving encouragement is a form of kindness and showing appreciation, be it through post engagements or telling me now.

The good thing about direct post engagement is that it benefits others, who may need the message more than us.

Since I started weekly uploads to YouTube in June, a lot more queries come in every month. A number of them know me, due to their FB friends sharing my videos on their timeline.

Thing is, their FB friend does not have a clue that they watched my video and came to seek my service.

We don’t go around telling the whole world our problems, you see.

Sometimes, it’s easier to tell a stranger who has the solutions, than a friend who can only tell you to think about happier things.

I have been posting online for 3.5 years and have met hundreds of people. Perhaps to you, it seems that I am helping people.

But like what Buddha says, the sentient beings are here to help us actualise our spiritual practice, to attain enlightenment and Buddhahood.

It is a reciprocal cycle. The more people I see, the more I realise how transient this Samsara world is. The more I write and film, the clearer I am in my thinking and aspirations.

I don't wish to have the kind of destinies I deal with, so I am more careful in my doings and thoughts. I see first-hand how greed, ignorance and anger can kill people, so I have opened up my heart to give out more love and let go of stubborn beliefs that benefit no one.

So thank you to you, you and you for helping me to be a better person and giving me a holy purpose in this life. I have never been happier in my entire lifetime and I want to do this for as long as I live.

I hope I can do the same for you, so that you will do the same for others too.