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#1Polyadenylation - Wikipedia
Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine ...
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#2多腺苷酸化- 维基百科，自由的百科全书
多腺苷酸化（英語：Poly-adenylation）是指多聚腺苷酸與信使RNA（mRNA）分子的共價鏈結。在蛋白質生物合成的過程中，這是產生準備作翻譯的成熟mRNA的方式的一部份。
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#3Polyadenylation - an overview | ScienceDirect Topics
Polyadenylation (polyA) signal sequences from various genes are added to mammalian vectors to ensure proper mRNA processing and stability.
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#4Alterations in Polyadenylation and Its Implications ... - Frontiers
Introduction: Polyadenylation is the process in which the pre-mRNA is cleaved at the poly(A) site and a poly(A) tail is added – a process ...
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#5Alternative polyadenylation of mRNA precursors - Nature
These two coupled reactions, collectively referred to as cleavage and polyadenylation or, simply, polyadenylation, are intimately linked to ...
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#6Alternative cleavage and polyadenylation: extent, regulation ...
Therefore, alternative polyadenylation (APA) is a widespread phenomenon, generating mRNAs with alternative 3′ ends. APA contributes to the ...
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#7Mechanisms and consequences of alternative polyadenylation
Alternative polyadenylation (APA) is emerging as a widespread mechanism used to control gene expression. Like alternative splicing, usage of ...
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#8Mechanism and regulation of mRNA polyadenylation - Genes ...
The majority of examples of polyadenylation regulated by auxiliary signals have been detected in the genomes of viruses and are commonly associated with ...
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#9Alternative Polyadenylation: a new frontier in post ...
Polyadenylation of pre-messenger RNA (pre-mRNA) specific sites and termination of their downstream transcriptions are signaled by unique ...
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#10Genome-wide landscape of polyadenylation in Arabidopsis ...
Alternative polyadenylation (APA) has been shown to play an important role in gene expression regulation in animals and plants.
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#11Polyadenylation (or Poly(A)) signal, site and tail - IMGT ...
The sequence elements for polyadenylation include the polyadenylation signal (POLYA_SIGNAL) and the polyadenylation site (POLYA_SITE). In mRNA ...
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#12Cytoplasmic Polyadenylation in Development and Beyond
SUMMARY Maternal mRNA translation is regulated in large part by cytoplasmic polyadenylation. This process, which occurs in both vertebrates ...
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#13Polyadenylation - NEJM Illustrated Glossary
The sequential addition of adenine bases to the 3′ end of pre–messenger RNA (pre-mRNA), thus forming a poly(A) tail. Polyadenylation is part of the maturation ...
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#14PolyASite 2.0: a consolidated atlas of polyadenylation sites ...
Abstract. Generated by 3′ end cleavage and polyadenylation at alternative polyadenylation (poly(A)) sites, alternative terminal exons ...
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#15Comprehensive Polyadenylation Site Maps in Yeast and ...
Here, we report comprehensive maps of global polyadenylation events in human and yeast generated using refinements to the Direct RNA Sequencing ...
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#16RNA polyadenylation and its consequences in prokaryotes
Polyadenylation refers to an enzymatic process carried out by poly(A) polymerase to add adenine residues to the 3′ extremity of RNAs.
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#17Different types of alternative polyadenylation and their possible...
A complex interaction between the cleavage and polyadenylation molecular complex and cis-elements determine the polyadenylation site, which may result in the ...
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#18Polyadenylation of Sine Transcripts Generated by RNA ...
The transcripts of some mammalian SINEs have an ability to undergo AAUAAA-dependent polyadenylation, which is unique for the RNA polymerase ...
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#19The Pattern of Alternative Polyadenylation | Plantae
Polyadenylation requires poly(A) signal recognition, cleavage, and addition of the A nucleotides. At least 50% of genes in humans, animals, ...
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#20Role of Arginine Methylation in Alternative Polyadenylation of ...
Mature mRNA is generated by the 3ʹ end cleavage and polyadenylation of its precursor pre-mRNA. Eukaryotic genes frequently have multiple polyadenylation ...
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#21A dynamic interplay between alternative polyadenylation and ...
Alternative polyadenylation and microRNA regulation are both mechanisms of post-transcriptional regulation of gene expression.
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#22Mechanisms of mRNA polyadenylation - DergiPark
All eukaryotic pre-mRNAs undergo polyadenylation, i.e. cleavage and polyadenylation at the 3' untranslated region (UTR), except replication-dependent histone ...
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#23Alternative Polyadenylation(APA) modulates extracellular ...
Alternative Polyadenylation(APA) modulates extracellular matrix deposition in pulmonary hypertension. S Collum, T Weng, A Hernandez, T Mertens, N Chen, ...
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#24Martinson - Cleavage and Polyadenylation
Cleavage and polyadenylation is directed by a poly(A) signal in the RNA. The core poly(A) signal for vertebrate pre-mRNAs consists of two recognition ...
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#25DeepPolyA: A Convolutional Neural Network Approach for ...
Polyadenylation (Poly(A)) plays crucial roles in gene regulation, especially in messenger RNA metabolism, protein diversification, ...
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#26Alternative polyadenylation and the stress response - Sadek
RNA Processing > 3′ End Processing. Abstract. Various stresses induce alternative polyadenylation of nascent transcripts modulating their ...
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#27Comprehensive characterization of alternative ...
Background: Alternative polyadenylation (APA) is emerging as a major post-transcriptional mechanism for gene regulation, and dysregulation ...
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#28Protein 1 of cleavage and polyadenylation factor 1 - Society ...
Pol II termination is coupled to polyadenylation by the polyadenylation signal in the nascent transcript. Two models have been proposed to ...
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#30Laminar Shear Stress and 3′ Polyadenylation of eNOS mRNA
The 3′ poly(A) tail is important in messenger RNA stability and translational efficiency. In somatic tissues, 3′ polyadenylation of mRNAs ...
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#31PolyA_DB -- A database for mammalian mRNA polyadenylation
The database provides several types of information regarding polyadenylation in mammalian species: (i) polyadenylation sites and their ...
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#32Polyadenylation of mRNA in bacteria | Microbiology Society
This review presents the accumulated evidence for the extensive 3′-polyadenylation of bacterial mRNA and for a complex enzymic machinery that ...
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#33Alternative polyadenylation of single cells delineates ... - PLOS
Alternative polyadenylation (APA) in 3' untranslated regions (3' UTR) plays an important role in regulating transcript abundance, ...
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#34RNA-seq Quantification of Alternative Polyadenylation (QAPA)
Analysis of alternative polyadenylation (APA) from RNA-seq data (human and mouse). QAPA consists of two main components: Extraction and annotation of 3′ UTR ...
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#35WikiGenes - Polyadenylation - Evolutionary Knowledge
Uridylate-containing RNA sequences determine specificity for binding and polyadenylation by the catalytic subunit of vaccinia virus poly(A) polymerase [4]. We ...
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#36PolyA-miner accurately assesses the effect of alternative ...
PolyA-miner enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease.
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#37Functional Interaction of BRCA1-Associated BARD1 ... - Science
Polyadenylation of messenger RNA precursors requires a complex protein machinery that is closely integrated with the even more complex transcriptional ...
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#38Cytoplasmic polyadenylation-mediated translational control of ...
Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal-to-zygotic transition · In the earliest stages of animal ...
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#39Polyadenylation Regulates the Stability of Trypanosoma ...
The role of polyadenylation in the turnover of mitochondrial RNAs is not well ... but polyadenylation of mature mRNA 3′-ends is correlated with reduced RNA ...
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#40cpsf-3 - Cleavage and Polyadenylation Specificity Factor
mRNA cleavage and polyadenylation specificity factor complex, 5'-3' exonuclease activity, endoribonuclease activity, RNA binding, mRNA 3'-end processing by ...
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#41Strange bedfellows: polyadenylation factors at the promoter
TFIID, RNA polymerase II, and the polyadenylation machinery. The story began back in 1997 with the discovery that the general transcription factor (GTF) ...
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#42The impact of cytoplasmic polyadenylation on local translation ...
In neurons, cytoplasmic polyadenylation of synaptic mRNAs plays a significant role in the regulation of protein synthesis. However, until now it was studied ...
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#43Polyadenylation - SlideShare
3. Polyadenylation is the addition of a poly(A) tail to a messenger RNA. The poly(A) tail consists of multiple adenosine monophosphates; in other ...
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#44Alternative Polyadenylation in Human Diseases - Semantic ...
Varying length of messenger RNA (mRNA) 3′-untranslated region is generated by alternating the usage of polyadenylation sites during pre-mRNA ...
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#45definition of polyadenylation by Medical dictionary
polyadenylation. addition of a sequence of ADENINE NUCLEOTIDES to the 3′-end of most eukaryotic RNA molecules, after their TRANSCRIPTION. The sequence is often ...
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#46Cleavage and polyadenylation of Intronless Pre-mRNA
Cleavage and polyadenylation of Intronless Pre-mRNA. Stable Identifier. R-MMU-77593. Type. Reaction [dissociation]. Species. Mus musculus. Compartment.
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#47Cleavage and polyadenylation of pre-mRNA - Malaria ...
PFID PFID Old Annotation PF3D7_0109200 PFA0450c CFI PF3D7_0403700 PFD0180c CFI PF3D7_1420000 PF14_0194 CFI
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#48RNA-Based Regulation in Human Health and Disease
Polyadenylation begins after a readthrough of a polyadenylation signal of “AAUAAA” [37]. A large complex is formed around this signal site and w15 bases ...
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#49Lecture 8.4 Capping and Polyadenylation - FLAX library
Here's a schematic of how polyadenylation occurs on a DNA template for most viruses except Poxviruses. We have, the top here is a mRNA in the process of being ...
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#50Lewin's Cells - 第 137 頁 - Google 圖書結果
In most cases, additional polyadenylation enhancer elements are located upstream and downstream of the cleavage site. (b) The poly(A) signal in yeast is ...
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#51Polyadenylation - WIKI 2
1 Background on RNA · 2 Nuclear polyadenylation. 2.1 Function; 2.2 Mechanism; 2.3 Downstream effects; 2.4 Deadenylation; 2.5 Alternative ...
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#52Polyadenylation – the process | The RNA Underworld
While the process of polyadenylation seems simple enough, it actually involves a rather large number of proteins (more than 20, if one counts ...
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#53RNA Biochemistry and Biotechnology - 第 262 頁 - Google 圖書結果
Polyadenylation Retroviruses with an extended R region encode the polyadenylation ( polyA ) signal within the R region , such that it is present at both the ...
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#543'-end Cleavage and Polyadenylation.
In eukaryotes, polyadenylation is part of the process that produces mature messenger RNA (mRNA) for translation. It, therefore, forms part of ...
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#55Molecular Biology and Genetic Engineering
Polyadenylation and the generation of 3 ' end in eukaryotes The 3 ' end of mRNA is generated in two steps ( Fig . cap Poly ( A ) 13.2 ) ( i ) Nuclease ...
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#56polyAdb - compbio.dundee.ac.uk
polyADB gives you information about, and access to, large polyadenylation-related datasets by providing ready-to-go, pre-processed, downloadable files in a ...
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#57BIOS Instant Notes in Biochemistry - 第 225 頁 - Google 圖書結果
3 processing: cleavage and polyadenylation snRNPs (see above), and since these sequences are different in the minor intron class, U1, U2, U4, ...
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#58RNA-Protein Interaction Protocols[ - 第 448 頁 - Google 圖書結果
Sallés, F. J. and Strickland, S. (1995) Rapid and sensitive analysis of mRNA polyadenylation states by PCR. PCR Methods Appl. 4, 317–321. 2.
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#59Cell and Molecular Biology of Plastids - 第 185 頁 - Google 圖書結果
3.1 Historical perspective on polyadenylation Polyadenylation is an important posttranscriptional modification of prokaryotic, eukaryotic and organellar RNA ...
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#60A series of BRAF- and NRAS-driven murine melanoma cell ...
... cell lines (M175M1 and M175M2) underwent an aberrant recombination reaction where the three SV40 polyadenylation signals and the 3' loxP ...
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#61Mmlv promoter - Whereat - Risto
Also facilitates transcription termination and mRNA polyadenylation in ES cells and other cell types. 1-Hygro-JY4-3XFlagN-GS3 vector ...
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#62Splicing lab - Medical Supply
... Our lab and others have shown that these three processes, transcription, splicing and polyadenylation, are all linked, or coupled, in interesting ways.
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#63The Dictionary of Cell and Molecular Biology
polyadenylation. distantly related, are usually heterodimers or multimers with a high and a low affinity component and signal through JAKs.
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#64Cumulated Index Medicus
Arerugi 1994 Jul ; 43 ( 7 ) : 800-8 ( Eng . common erythroid - specific promoter and alternative usage Abstr . ) ( Jpn ) of different polyadenylation ...
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#65VMC 211: General Veterinary Microbiology (1+1) - Course
Capping & Polyadenylation Page · Genome replication Page · Assembly and release Page · PODCAST File · Quiz. Topic 20. Click here... Viral genetics.
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#66Mesv promoter
The LTRs carry both promoter and polyadenylation function, such that the 5' LTR acts as a promoter to drive the transcription of the viral genome, ...
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#67Biology test 1 answers - Golf Refugees
ANSWERS TO BIOLOGY TEST 2 Answers to Biology Test Part I Question 1 (a) during polyadenylation, what is the pre-mRNA sequence's function corresponding to ...
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#68Protein sequence classification kaggle
... Atlas Image Classification. pep) ssRNA classification of viruses) about 30 kb in length that has a 5′ cap structure and 3′ polyadenylation tract.
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#69Joseph Heimiller - Bioinformatics Research Scientist - LinkedIn
The loss of FUS leads to RNAP2 accumulation at the transcription start site and a shift in mRNA isoform expression toward early polyadenylation sites.
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#70Mmlv promoter
Also facilitates transcription termination and mRNA polyadenylation in ES cells and other cell types. T7 RNA polymerase produces multiple copies of RNA ...
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