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#1Pam3CSK4 | Cell Culture Tested TLR2/TLR1 Agonist
Pam3CSK4 (Pam3CysSerLys4) is a synthetic triacylated lipopeptide (LP) and a TLR2/TLR1 ligand. It is a potent activator of the pro-inflammatory transcription ...
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#2Pam3CSK4 (CAS 112208-00-1) - R&D Systems
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist; induces production of TNF-α and IL-6 in macrophages. Stimulates phosphorylation of p100/p110 and p60 ...
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#3Pam3CSK4, TLR1 and TLR2 Ligand (NBP2-25297) - Novus ...
Pam3CSK4, TLR1 and TLR2 Ligand is a synthetic tripalmitoylated lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein.
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#4Toll-like Receptor 1/2 Agonist Pam3CSK4 Suppresses ... - NCBI
To further elucidate the role of Pam3CSK4 in B cell growth and Ig production, we stimulated resting B cells with various doses of Pam3CSK4 and ...
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#5[InvivoGen] Pam3CSK4 - 다윈바이오
Pam3CSK4 (Pam3CysSerLys4)는 synthetic triacylated된 lipopeptide (LP) 및 TLR2/TLR1 ligand 입니다. Pam3CSK4는 pro-inflammatory transcription factor인 NF-κB의 ...
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#6Pam3CSK4 - Creative Diagnostics
Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs. Pam3CSK4 is a potent activator of the ...
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#7Toll-Like Receptor 2 Agonist Pam3CSK4 Alleviates the ...
The TLR2 agonist Pam3CSK4 improves the survival rate, alleviates the pathology of leptospirosis, and decreases the abundance of leptospires in ...
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#8Molecular modelling of TLR agonist Pam3CSK4 entrapment in ...
vectorize Pam3CSK4, a lipopeptide TLR1/2 ligand and a potent activator of the ... PLA nanoparticles, Toll-Like-Receptor, Pam3CSK4, immune modulation, ...
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#9Pam3CSK4 (4633) | Bio-Techne
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist; induces production of TNF-α and IL-6 in macrophages. Stimulates phosphorylation of p100/p110 and p60 ...
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#10Pam3CSK4 - APExBIO
Pam3CSK4 is an agonist of Toll-like receptor 1/2 (TLR1/2) [1]. Toll-like receptors (TLRs) are proteins that play an important role in the innate immune ...
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#11PAM3CSK4 Non-Endotoxin Pyrogen (NEP) Control - Sigma ...
PAM3CSK4 Non-Endotoxin Pyrogen (NEP) Control for use with PyroMAT®; Synonyms: Triacylated Lipopeptide,Lipopeptide; find Millipore-MATPAM3CSK4 MSDS, ...
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#12Pam3CSK4 Induces MMP-9 Expression in Human Monocytic ...
The synthetic bacterial triacylated lipopeptide Pam3-Cys-Ser-Lys4 (Pam3CSK4) is a potent activator of the proinflammatory transcription factor ...
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#13Combination of poly I:C and Pam3CSK4 enhances activation ...
Poly I:C and Pam3CSK4 together are an effective adjuvant system capable of boosting antibody responses in vivo when administered with protein ...
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#14Pam3CSK4 | Ligand page - IUPHAR/BPS Guide to ...
The IUPHAR/BPS Guide to Pharmacology. Pam3CSK4 ligand page. ... Pam3CSK4 Click here for help. GtoPdb Ligand ID: 8558 ...
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#15Pam3CSK4
Pam3cSK4 stimulation. - Transfect your cell line with an NF-κB-inducible reporter plasmid, i.e. a plasmid carrying a reporter gene, such as SEAP.
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#16pam3csk4 - List of Frontiers' open access articles
Original Research macrophages derived from HSPCs in vivo-exposed to Pam3CSK4 (a TLR2 agonist) or C. albicans infection. Short. Published on Sep 3, 2018.
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#17Detection of the Lipopeptide Pam3CSK4 Using a Hybridized ...
Electrochemical detection of Pam3CSK4, a synthetic triacylated lipopeptide that mimics the structural moieties of its natural Gram negative ...
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#18The inflammatory cytokine effect of Pam3CSK4 TLR2 agonist ...
Whole blood was stimulated with medium alone (Ø), LSA, concanavalin A, TLR2 (Pam3CSK4) receptor agonist (Ø + TLR2a) and TLR2a and LSA (LSA + ...
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#19The TLR1/2 agonist PAM3CSK4 instructs commitment of ...
In this work, we have explored the impact of TLR ligands (TLR-L) on human hematopoietic stem cells (HSCs) and hematopoietic progenitor cells ( ...
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#20Pam3CSK4 (Pam3Cys-Ser-(Lys)4) | TLR1/2 Agonist
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2. - Mechanism of Action & Protocol.
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#21Pam3CSK4 TFA (112208-00-1 free base) - TargetMol
Pam3CSK4 TFA is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2).
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#22CEP synergizes with the TLR2-agonist Pam3CSK4 to induce ...
Download scientific diagram | CEP synergizes with the TLR2-agonist Pam3CSK4 to induce inflammatory gene expression. (A, B, C, D, E, F) BMDMs were stimulated ...
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#23Pam 3 CSK 4 (trifluoroacetate salt) - Cayman Chemical
Pam3CSK4 (trifluoroacetate salt). Item No. 24126. Pam3CSK4 (trifluoroacetate salt) (Pam3Cys-Ser-(Lys)4).
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#24Pam3CSK4 | CAS 112208-00-1 | Cayman Chemical - Biomol ...
Pam3CSK4 is a synthetic bacterial lipopeptide that binds to and acts as an agonist at toll-like receptor 2 (TLR2). It induces proliferation of isolated ...
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#25Novus Biologicals™ Pam3CSK4, TLR1 and TLR2 Ligand
Synthetic tripalmitoylated lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein Shop Novus Biologicals™ Pam3CSK4 ...
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#26Pam3CSK4, 1 mg - Jomar Life Research
Synthetic triacylated lipopeptide. Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.
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#27Pam3CSK4, TLR1 and TLR2 Ligand from Novus Biologicals
Compare Pam3CSK4, TLR1 and TLR2 Ligand from Novus Biologicals on Biocompare.com.
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#28MF59 and Pam3CSK4 Boost Adaptive Responses to Influenza ...
By blocking IFN type I receptor through a mAb, we confirmed that the adjuvanticity of MF59 and Pam3CSK4 to a trivalent influenza vaccine and to ...
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#29Anti-neuroinflammatory effect of curcumin on Pam3CSK4 ...
In the present study, the inhibitory effects of curcumin on the inflammatory mediators released by Pam3CSK4-stimulated BV-2 microglial cells ...
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#30Metabolomics assessment of vitamin D impact in Pam3CSK4 ...
The obtained data was subjected to chemometric modelling and statistical analyses, which revealed a clear distinction between the metabolic profiles of Pam3CSK4 ...
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#31前列腺素E2促进Pam3CSK4诱导的牛子宫内膜上皮细胞炎症。
Prostaglandin E2 promotes Pam3CSK4-induced inflammation in endometrial epithelial cells of cattle. Animal Reproduction Science ( IF 2.145 ) Pub Date : 2018-11- ...
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#32TLR1/2 ligand enhances antitumor efficacy of CTLA-4 ... - PNAS
Intratumoral injections of Pam3CSK4 or Vehicle were given only on right flank. Survival (Top) and average tumor growth (Bottom) of mice in each ...
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#33Pam3CSK4 | 1 mg | InvivoGen - Bio-Connect
Pam3CSK4 | Catalog number: tlrl-pms | Size: 1 mg | Order all your InvivoGen products on bio-connect.nl.
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#34Pam3CSK4 - Abeomics
Pam3CSK4 ; Application : Functional Assay ; Amount : 1 mg ; Content : (1mg/ml) in Sterile Water ; Storage condition : Store the product at 4°C for short term and at ...
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#35CAS 112208-00-1 Pam3CSK4 - BOC Sciences
Pam3CSK4 is a TLR 1/2 agonist and a cell-permeable, water-soluble synthetic tripalmitoylated lipopeptide that mimics the acylated amino terminus of ...
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#36VacciGrade™ Pam3CSK4, Triacylated Lipopeptide | VWR
VacciGrade™ Pam3CSK4, Triacylated Lipopeptide ... This is a synthetic lipopeptide and a TLR2/1 ligand. ... It has been reported to efficiently increase antibody ...
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#37Synergistic Anticancer Effects of Pam3CSK4 and Ara-C on B ...
Consistent with an increased immunogenicity of Pam3CSK4 and Ara-C–treated B-cell lymphoma cells, rejection of cotreated tumor cells required ...
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#38Differential Effects of the Toll-like Receptor 2 Agonists, PGN ...
This study aims to compare the effects of the TLR2 agonists peptidoglycan (PGN) and tripalmitoyl-S-glycero-Cys-(Lys)4 (Pam3CSK4) on SP-induced human mast ...
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#39Pam3CSK4 in PDB entry 2z7x ‹ PDBe ‹ EMBL-EBI
PDB 2z7x contains 1 copy of Pam3CSK4 in assembly 1. This protein is highlighted and. Chain: C Length: 5 amino acids. Theoretical weight: 622 Da Source organism ...
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#40Pam3CSK4 HCl | CAS#112208-00-1 | TLR1/2 agonist | MedKoo
Pam3CSK4 is a TLR1/2 agonist. Pretreatment of Pam3CSK4 attenuates inflammatory responses caused by systemic infection of methicillin-resistant ...
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#41Crystal Structure of the TLR1-TLR2 Heterodimer Induced by ...
The three lipid chains of Pam3CSK4 mediate the het- erodimerization of the receptor; the two ester- bound lipid chains are inserted into a pocket in TLR2, while ...
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#42Effect of Pam3CSK4 (TLR2/1 ligand) and Pam2CSK4 (TLR2/6 ...
Effect of Pam3CSK4 (TLR2/1 ligand) and Pam2CSK4 (TLR2/6 ligand) on 5-HT transepithelial flux and resistance.
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#43Pam3CSK4, a TLR2 Agonist, Induces Osteoclastogenesis in ...
To clarify whether Pam3CSK4, a TLR2 agonist, induces the differentiation of osteoclasts, we investigated the osteoclastogenesis and gene expression induced ...
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#44Figure 2 - JCI Insight
Figure 2. Intra-articular injection of synthetic TLR2 ligand, Pam3CSK4, induces knee hyperalgesia in naive mice. Options: View ...
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#45Pro-inflammatory response ensured by LPS and Pam3CSK4 ...
Pro-inflammatory response ensured by LPS and Pam3CSK4 in RAW 264.7 cells did not improve a fungistatic effect on Cryptococcus gattii ...
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#46대식세포에서 Pam3CSK4로 유도된 면역관용의 NF-κB/MAPK ...
Anti-inflammatory Effect of Tolerance Induced by Pam3CSK4 in Murine Macrophage RAW 264.7 Cells via Inhibitor of NF-κB/MAPK Signaling Pathway - tolerance ...
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#47Pam3CSK4 - CPC Scientific
Pam3CSK4. $590.00 – $2,950.00. Pam4-001. Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ser-Lys-Lys-Lys-Lys-OH (trifluoroacetate salt) ...
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#48Pam3CSK4 | CAS:112208-00-1 | TLR1/2 agonist - BioCrick
BioCrick is a famous high-purity reference standards manufacturer. Our Pam3CSK4 is confirmed by NMR. Order now can get a discount!
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#49The TLR1/2 agonist PAM3CSK4 instructs commitment
The TLR1/2 agonist PAM3CSK4 instructs commitment of human hematopoietic stem cells to a myeloid cell fate. De Luca, K; Frances-duvert, V; Asensio, M-j; ...
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#50Pam3CSK4——TLR1/2激动剂- 产品资讯 - 生物在线
Pam3CSK4 是一种合成的三酰脂肽，是模拟细菌LPS的酰化氨基端。Pam3CSK4可有效的活化促炎转录因子NF-κB，这一过程是由于TLR1和TLR2的相互作用调节的。
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#51Reactivation of latent HIV-1 in central memory CD4+ T cells ...
The TLR-1/2 agonist Pam3CSK4 leads to viral reactivation of quiescent HIV in a model of latency based on cultured TCM and in resting CD4+ T cells isolated ...
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#52Avaliação do papel do agonista de TLR1\2 (PAM3CSK4) na ...
Título: Avaliação do papel do agonista de TLR1\2 (PAM3CSK4) na potencialização do efeito protetor da vacina LaAg administrada por via intranasal contra a ...
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#53Pretreatment of Pam3CSK4 attenuates inflammatory ...
Pretreatment of Pam3CSK4 attenuates inflammatory responses caused by systemic infection of methicillin-resistant Staphylococcus aureus in mice.
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#54Agonistic targeting of TLR1/TLR2 induces p38 MAPK ...
By using murine Trp53 −/− MLL-AF9 AML cells, we demonstrate that p53 is dispensable for Pam3CSK4-induced apoptosis and differentiation. Moreover ...
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#55Pam3CSK4 enhances adaptive immune responses to ...
Pam3CSK4 enhances adaptive immune responses to recombinant Mycobacterium bovis bacille Calmette-Guérin expressing Plasmodium falciparum C-terminus merozoite ...
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#56NBP2-25297 Pam3CSK4, TLR1 and TLR2 Ligand - 瑞柏生物 ...
型號：NBP2-25297. 中文名稱：Pam3CSK4, TLR1 and TLR2 Ligand. 英文名稱：Pam3CSK4, TLR1 and TLR2 Ligand. 包裝單位：0.025 mg. 廠牌：Novus. 售價：與我們聯絡.
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#57Pam3CSK4 Pam3CSK4 - 富士フイルム和光純薬 - FUJIFILM ...
TLRは、マクロファージ、Bリンパ球などの免疫細胞やマスト細胞での発現が見られ、自己免疫疾患・炎症系疾患への関与が注目されています。 □アゴニスト Pam3CSK4. TLR1/2の ...
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#58各種Toll-Like Receptorのリガンド | TLR Ligand | フナコシ
Pam3CSK4 ，Zymosan，MALP-2，LPS，Flagellin，CpG ODNなどを取りそろえています。TLRは膜貫通型レセプターで，自然免疫における病原体の認識に必須とされています。
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#59Advances in Lymphatic System Research and Application: 2012 ...
(2011 AUG 22) Researchers' Work from Research Center Julich Focuses on Influenza Vaccines Current study results from the report, “MF59 and Pam3CSK4 Boost ...
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#60Cardiovascular Diseases: Nutritional and Therapeutic ...
Pretreatment of the hearts with Pam3CSK4, a synthetic ligand specific for TLR2, significantly improved LV functional recovery following I/R (Dong et al.
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#61Roles of PRR-Mediated Signaling Pathways in the Regulation ...
TLR1, TLR2, and TLR4 recruit MyD88 and TRAF6 to activate the NF-κB and MAPK pathways under the action of the ligand Pam3CSK4 or LPS, which can trigger the ...
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#62Employing Biomaterials to Further Basic Understanding of ...
Primed T cells were isolated with the negative selection cocktail described above. with soluble lipid-CpG (5μM), Pam2CSK4 (10μg/mL), and/or Pam3CSK4 ...
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#63Pattern Recognition Receptors—Advances in Research and ...
In vitro, LPS and Pam3CSK4 induced IL-6 production in splenocytes, and in vivo, LPS-induced IL-6 were suppressed in GS/GS mice.
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#64Middle Molecular Strategy: Flow Synthesis to Functional ...
In 2007, Boons et al. synthesized a three-component conjugate vaccine 15 composed of MUC1 glycopeptide overexpressed in human breast cancer cells, Pam3CSK4 ...
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#65Issues in Cancer Epidemiology and Research: 2011 Edition
B-CLL cells also respond to the stimulation with loxoribine, Pam3CSK4 and MALP-2 (TLR-7, TLR1/TLR2 and TLR2/TLR6 agonists, respectively).
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#66CU-CPT22 is a TLR1-TLR2 Complex Inhibitor - Immune ...
CU-CPT22 is a potent protein complex of TLR1/2 inhibitor, competes with Pam3CSK4 binding to TLR1/2, and suppresses TLR1/2-mediated ...
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#67Antiphospholipid Antibodies and Syndrome - 第 97 頁 - Google 圖書結果
LPS and Pam3CSK4 upregulated procoagulant activity and induced a massive release of TNFα from U937 cells (Figure 3C,D).
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#68The Non-Thrombotic Role of Platelets in Health and Disease
Pam3CSK4, a synthetic agonist of the TLR2/1 complex, triggers platelet activation including integrin αIIbβ3 transition to an active state, aggregation, ...
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