雖然這篇Myofibroblast鄉民發文沒有被收入到精華區：在Myofibroblast這個話題中，我們另外找到其它相關的精選爆讚文章
[爆卦]Myofibroblast是什麼？優點缺點精華區懶人包
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#1Myofibroblast - Wikipedia
A myofibroblast is a cell phenotype that was first described as being in a state between a fibroblast and a smooth muscle cell.
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#2Fibroblasts and Myofibroblasts: What are we talking about?
Myofibroblasts are large cells with ruffled membranes and highly active endoplasmic reticulum (Figure 1B). Myofibroblasts are not part of normal cardiac tissue ...
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#3Myofibroblast - an overview | ScienceDirect Topics
A myofibroblast is an activated form of fibroblast that is capable of contraction due to the presence of cytoskeletal proteins that are normally found in smooth ...
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#4Mechanical and Physical Regulation of Fibroblast ... - Frontiers
A key step in wound healing, but also in fibrotic pathological diseases, is the activation of the fibroblast to become myofibroblast, where they ...
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#5Fibroblasts and myofibroblasts in wound healing | CCID
It is generally accepted that the major source of myofibroblasts are local connective tissue fibroblasts that are recruited into the wound.
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#6Myofibroblasts and mechano-regulation of connective tissue ...
Myofibroblasts are the predominant cell type that are present in granulation tissue of contracting wounds and fibrocontractive diseases, ...
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#7Myofibroblasts and Fibrosis | Circulation Research - AHA ...
Myofibroblasts are a specialized cell type that are responsible for the pathological remodeling observed in tissue organ fibrosis. Numerous ...
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#8The myofibroblast at a glance | Journal of Cell Science - The ...
In his seminal work, Gabbiani proposed myofibroblasts as “modified fibroblasts that have developed from the more conventional tissue fibroblasts ...
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#9Collagen microarchitecture mechanically controls ... - PNAS
Myofibroblasts are key players of both physiological and ... Consequently, examining myofibroblast differentiation as a function of varying ...
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#10The myofibroblast, multiple origins for major roles in normal ...
Myofibroblasts differentiate, invade and repair injured tissues by secreting and organizing the extracellular matrix and by developing ...
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#11Signaling Mechanisms of Myofibroblastic Activation - Karger ...
Key Words: MyofibroblastExtracellular matrixTGF-β1EDA-FNPositive ... The central cellular mediators of fibrosis are myofibroblasts with a ...
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#12Myofibroblasts: Function, Formation, and Scope of Molecular ...
Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple ... This comprehensive review article describes the myofibroblast cell ...
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#13The two-stage model of myofibroblast differentiation.In vivo
Proto-myofibroblasts also express and organize cellular fibronectin — including the ED-A splice variant — at the cell surface. Functionally, these cells can ...
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#14Discovering Novel Regulators of Myofibroblast Biology - Mayo ...
The Tschumperlin Tissue Repair & Mechanobiology Lab at Mayo Clinic is identifying novel gene & molecular regulators of myofibroblast function in fibrosis.
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#15Myofibroblast differentiation during fibrosis: role of NAD(P)H ...
In renal disease, glomerular mesangial cells also acquire a myofibroblast phenotype and synthesize the same matrix proteins. The origin of interstitial ...
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#16Evolution and clinical implications of the myofibroblast concept
Time for primary review 21 days. 1 Development of the myofibroblast concept. The phenomena of wound contraction and scar retraction are known since old ages ...
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#17The Myofibroblast - The American Journal of Pathology
After tissue injury, fibroblasts differentiate into contractile and secretory myofibroblasts that contribute to tissue repair during wound healing, but that can ...
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#18Fibroblast-to-Myofibroblast Transition (FMT) Assay - Charles ...
A validated, robust TGF-β1-induced fibroblast-to-myofibroblast transition (FMT) assay has been developed in idiopathic pulmonary fibrosis (IPF)-derived ...
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#19Stromal myofibroblasts are drivers of invasive cancer growth
Myofibroblasts are large spindle-shaped cells defined by indented nuclei, stress fibers and well-developed cell-matrix interactions (fibronexus) ...
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#20Myofibroblast dedifferentiation proceeds via distinct ...
Myofibroblasts are the major cellular source of collagen, and their accumulation — via differentiation from fibroblasts and resistance to apoptosis — is a ...
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#21Myofibroblast Markers and Microscopy Detection Methods in ...
The identification of myofibroblasts is essential for mechanistic in vitro studies, cell-based drug tests, and to assess the level of ...
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#22Myofibroblast proliferation and heterogeneity are supported by ...
During tissue repair, myofibroblasts produce extracellular matrix (ECM) molecules for tissue resilience and strength. Altered ECM deposition can lead to ...
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#23Myofibroblast or Smooth Muscle | Do In Vitro Systems ...
In addition, myofibroblasts can produce calponin, desmin, and numerous other putative ASM cell markers, such that it is virtually impossible to distinguish them ...
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#24Engineered Fibrous Networks To Investigate the Influence of ...
As a model myofibroblast precursor, primary hepatic stellate cells were seeded onto fibers with either low (soft) or high (stiff) cross-link ...
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#25Myofibroblast: the great ignored of wound healing - Elena ...
Myofibroblasts are essential for collagen production and wound contraction, but their excessive activity can produce pathological scars.
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#26Notch activity is required for myofibroblast differentiation
Notch activity is required for myofibroblast differentiation. Ana Pardo Saganta, Laura Vera Alvarez, Eva Petri, Felipe Prósper Cardoso, Javier Zulueta ...
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#27Origin and role of hepatic myofibroblasts in hepatocellular ...
Liver myofibroblasts are believed to transform into cancer-associated fibroblasts (CAFs) while HCC is developing. There is substantial evidence ...
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#28Myofibroblast - BioRender | Life Science Icons
Myofibroblast · Use this icon in BioRender along with 1000s of others to make your next science figure in minutes · Keywords · Other icons in Muscle Cells:.
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#29Mechanoregulation of the Myofibroblast in Wound Contraction ...
In normal acute wounds, myofibroblasts are transiently present and orchestrate time limited and spatially restricted scarring. However, when myofibroblasts ...
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#30Myofibroblast - DocCheck Flexikon
Myofibroblasten sind ein Zelltyp, der histologisch eine Zwischenform zwischen einem Fibroblasten und einer glatten Muskelzelle repräsentiert.
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#32Tissue Repair, Contraction and the Myofibroblast
Hypoxia Induces Proangiogenic Activation of Hepatic Stellate Cell-Derived Myofibroblasts in Avascular Micrometastases: Implications on Intratumoral ...
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#33WOUND HEALING, FIBROSIS, AND THE MYOFIBROBLAST: A Historical ...
In particular, it would be important to distinguish distinct fibroblastic phenotypes involved in myofibroblast differentiation, collagen and/or α-SMA ...
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#34myofibroblast | Dupuytren Research Group
Dupuytren's is truly a biomechanical process, and the ultimate process has to do with the way that fibroblasts and myofibroblasts attach to each ...
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#35Peroxynitrite augments fibroblast-mediated tissue remodeling ...
However, the contribution of RNS to myofibroblast differentiation, ... mechanism of differentiation of lung fibroblasts to myofibroblasts by peroxynitrite.
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#36Myofibroblast Matrix Metalloproteinases Activate the ...
Myofibroblast Matrix Metalloproteinases Activate the Neutrophil Chemoattractant CXCL7 From Intestinal Epithelial Cells ... Background & Aims: The ...
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#37FGF2-mediated attenuation of myofibroblast activation is ...
FGF2-mediated attenuation of myofibroblast activation is modulated by distinct MAPK signaling pathways in human dermal fibroblasts.
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#38The myofibroblast in health and disease - Elsevier
The myofibroblast is essential for the integrity of the mammalian body by virtue of its role in wound-healing, but it can also threaten it by its ability to ...
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#39Bone Marrow Cells in Murine Colitis: Multi-Signal Analysis ...
We consistently observed donor-derived pericryptal myofibroblasts that ... Colitis: Multi-Signal Analysis Confirms Pericryptal Myofibroblast ...
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#40Myofibroblast repair mechanisms post-inflammatory response
FindingsAs the effector cells of repair, myofibroblasts migrate to ... Myofibroblast activity is a decisive factor in whether a tissue is ...
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#41Activated mTORC1-SIRT6 Mediates Myofibroblast ...
Fibroblast-to-myofibroblast transdifferentiation and myofibroblast hyperproliferation plays a major role in pulmonary fibrosis.
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#42Nitric Oxide Synthase 3 Gene Transcriptional Regulation In ...
Rat and human NOS3 was used to transfect myofibroblast cells, ... was active in the rat pulmonary myofibroblasts with the human NOS3 promoter showing little ...
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#43The myofibroblast and its tumours - Journal of Clinical Pathology
ABSTRACT. Tumours and tumour-like lesions of myofibroblasts may present diagnostic difficulty because of their rarity and.
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#44肌成纤维细胞_百度百科
肌成纤维细胞概述. 编辑 语音. 中文名称：肌成纤维细胞. 英文名称：myofibroblast. 定义：肌成纤维细胞是指含有肌动蛋白、肌球蛋白和其他肌肉蛋白的成纤维样细胞。
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#45Role of myofibroblast in pseudointima formation - Surgery
The luminal cells that were seen were myofibroblasts containing microvilli rather than true endothelial cells. A gradual transition of fibroblast to ...
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#46Vitamin D inhibits TGF-&beta
857 Vitamin D inhibits TGF-b1-induced myofibroblast differentiation and extracellular matrix production via Smad2/3 signaling pathway in.
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#47Yale Cancer Center Researchers Show Receptor Structure ...
... as anaplastic lymphoma kinase is a driver of several cancers, including pediatric neuroblastoma, B-cell lymphomas, and myofibroblast tumors,
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#48Remodeling of cardiac passive electrical properties and ...
in our myofibroblast preparation, but was less prominent than either Nav 1.9 or ... 2012) that first identified Na+ current in human atrial myofibroblasts.
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#49Myofibroblasts vs Smooth Muscle Made Easy - KiKoXP
Myofibroblasts /fibroblasts often get confused with smooth muscle because they are all spindle cells that form fascicles.
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#50Key Players in Systemic Sclerosis: The Immune System and Beyond
In skin, the presence of myofibroblasts correlates with the amount of (hyalinized) ... Here, myofibroblast presence results in loss of muscle function, ...
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#51Insilico Medicine Initiates First-in-Human Study of ISM001-055 ...
The compound significantly improved myofibroblast activation which contributes to the development of fibrosis. ISM001-055's novel target is ...
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#52Wound Healing, Fibrosis, and the Myofibroblast - Pinterest
Apr 16, 2021 - Buy Wound Healing, Fibrosis, and the Myofibroblast : A Historical and Biological Perspective (Paperback) at Walmart.com.
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#53Sub-chronic oral exposure of tungsten induces markers ... - DOI
During 3-months of tungsten exposure, murine kidneys demonstrated significant increases in the myofibroblast marker ⍺SMA, and extracellular ...
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#54Zoledronic acid targets the mevalonate pathway causing ...
In this study, administration of ZA reduced myofibroblast transition and blocked NF-kB signaling in macrophages leading to impaired immune ...
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#55Insilico starts human trial with AI-discovered drug - Longevity ...
The compound significantly improved myofibroblast activation which contributes to the development of fibrosis. ISM001-055's novel target is ...
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#56Sub-chronic oral exposure of tungsten induces markers of ...
During 3-months of tungsten exposure, murine kidneys demonstrated significant increases in the myofibroblast marker ⍺SMA, and extracellular ...
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#57Insilico Medicine begins first human trial of its AI-designed ...
Insilico said the compound showed preliminary improvements in activating the myofibroblast cells that are essential for repairing damaged ...
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#58Insilico Medicine initiates first-in-human st | EurekAlert!
The compound significantly improved myofibroblast activation which contributes to the development of fibrosis. ISM001-055's novel target is ...
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#59Blade Therapeutics Announces Positive Topline Data from ...
LPA binds to LPA receptors on myofibroblasts, thereby triggering a signaling cascade that leads to myofibroblast activation/differentiation.
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#60인실리코, IPF 약물 “발굴→임상진입, 단 18개월” - 바이오스펙 ...
... 의 약동학과 안전성을 확인했고 섬유증(fibrosis) 유발에 관여하는 근섬유아세포(myofibroblast)의 활성화 억제 효과를 확인했다는 설명이다.
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#61First-in-human study of AI-discovered drug - ScienceBlog.com
The compound significantly improved myofibroblast activation which contributes to the development of fibrosis. ISM001-055's novel target is ...
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#62Environmental and Occupational Medicine - 第 266 頁 - Google 圖書結果
Myofibroblasts , which possess features of fibroblasts and smooth muscle ... The extent of fibrogenesis and myofibroblast induction correlates with the ...
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#63Dr. Zea Borok, MD | San Diego, CA | Pulmonologist - US News ...
Secondary crest myofibroblast PDGFRα controls the elastogenesis pathway via a secondary tier of signaling networks during alveologenesis.
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#64experimentally - 検索 - バイオマーケットjp
Myofibroblast transdifferentiation is associated with changes in cellular and extracellular vesicle miRNA abundance: (exsome) .
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#65Subset Seurat V3
Activation of hepatic stellate cells (HSCs) and their trans-differentiation towards collagen-secreting myofibroblasts (MFB) promote liver fibrosis ...
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#66Refrat Hipertensi Portai BLM Edit | PDF - Scribd
... sel stellat/ sel bintang hepatis diaktivasi dan fenotip sel diubah dari sel diam menjadi sel myofibroblast-like (sel mirip dengan miofibroblas).
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#67Pediatric Emergency Playbook: MI in Children
Thrombi may calcify, or the lumen may become stenotic due to myofibroblast proliferation. Children with any coronary artery dilatation from ...
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#68PeterCoNet✊️ on Twitter: "これまでの私の最も重要 ...
... amplify these profibrotic signals in the promotion of myofibroblast accumulation and the production of ECM to cause fibrosis.
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