受非法捕獵、棲息地減少及破碎化等威脅，極危的蘇門答臘犀牛只餘下少於100隻。研究發現牠們保留了比預期中多的遺傳多樣性，即牠們有較好的基因對抗氣候變化及疾病。可惜族群細小，當中出現輕微的近親繁殖，令研究團隊非常擔憂，因過去就有一個群族因突發爆發近親繁殖而導致整個滅絕。 There only fewer than 100 of critically endangered Sumatran rhinos, and they are mainly threatened by poaching, habitat loss and fragmentation. Research found they retain higher genetic diversity as expected, means they are more likely to survive threats like climate change or disease. However, with small population size they show low levels of inbreeding. This worries the researchers because another subpopulation showed a sudden outbreak of inbreeding before their extinction.

日本的小笠原琉璃灰蝶因受外來入侵物種的威脅，於2000年被列為瀕危物種。2005年起科學家嘗試人工繁殖但一直未成功，到近日他們的成蝶及幼蟲全部死亡，相信與近親繁殖有關。自2016年已無法在野外發現牠們，相信將會成為首種滅絕的日本蝴蝶。 A blue butterfly,Celastrina ogasawaraensis, endemic to the Ogasawara Islands of Japan, was listed as endangered species in 2000; they were mainly threatened by invasive species. there are breeding program since 2005, but without any success, and all the adults and larvae were dead recently which might be caused by inbreeding. Since 2016, there are no field record of this butterfly and this species might be the first Japanese butterfly species to go extinct.

美國聖莫尼卡山的美洲獅是受保護動物，但當地有一隻雄獅因三次捕食同一財產者的家畜，該財產者成功申請合法處死這隻雄獅。雖然這雄獅是在這法例覆蓋範圍外捕殺了這些家畜，但當地漁業和野生動物局表示，該財產者證明已用盡方法保護自己的財產，所以獲批許可證。當區美洲獅的棲息地被市區發展破壞導致生境破碎，僅存的細小群族裡只有兩隻已認知而有繁殖能力的雄性，其中一隻就是這隻被合法處死的雄獅。保育團體擔心這群族近親繁殖問題會更加嚴重。 Mountain lions are protected species in the Santa Monica Mountain. Recently, one male was killed legally because it harmed livestocks owned by the same property owner for three times. Even though the incidents took place outside the area covered by the State policy, the California Department of Fish & Wildlife explained that the property owner had already tried to use non-lethal means to protect the property before getting the permit for killing this lion was issued. Mountain lions in that area are threatened by urbanization and habitat fragmentation. there were only two known breeding males in this small population, and this male lion was one of them. Biologists that study this group of lions are working on the inbreeding problem will get worse.