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#1EIF2AK3 - Wikipedia
Eukaryotic translation initiation factor 2-alpha kinase 3, also known as protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), is an enzyme that ...
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#2EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation ...
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#3EIF2AK3 Gene - GeneCards | E2AK3 Protein
EIF2AK3 (Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3) is a Protein Coding gene. Diseases associated with EIF2AK3 include ...
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#4Eukaryotic translation initiation factor 2-alpha kinase 3 - UniProt
Eukaryotic translation initiation factor 2-alpha kinase 3 · EIF2AK3 · <p>This section provides any useful information about the protein, mostly biological ...
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#5EIF2AK3 protein expression summary
Gene name, EIF2AK3 (HGNC Symbol). Synonyms, PEK, PERK. Description, Eukaryotic translation initiation factor 2 alpha kinase 3 (HGNC Symbol). Chromosome, 2.
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#6EIF2AK3 - an overview | ScienceDirect Topics
EIF2AK3. In contrast, EIF2AK3 gene mutations, which cause Wolcott Rallison syndrome, are the leading cause of NDM in consanguineous populations. From: ...
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#7Eif2ak3 | Sigma-Aldrich
eif2ak3 ; PrEST Antigen EIF2AK3. APREST72252. Prestige Antigens ™ Powered by Atlas Antibodies, buffered aqueous solution ; Monoclonal Anti- ...
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#8Eif2ak3 MGI Mouse Gene Detail - MGI:1341830
View mouse Eif2ak3 Chr6:70821499-70882229 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.
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#9Eif2ak3 (eukaryotic translation initiation factor 2 alpha kinase 3)
ENCODES a protein that exhibits eukaryotic translation initiation factor 2alpha kinase activity; Hsp90 protein binding; protein serine/threonine kinase ...
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#10Mouse Monoclonal Anti-EIF2AK3 Antibody (Clone: 1385CT582)
AM8570b | Mouse Monoclonal Anti-EIF2AK3 Antibody (Clone: 1385CT582.4.39). Anticorps, Protéines recombinantes, coffret ELISA, RNAi, clones ADNc, ...
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#11EIF2AK3, GST-tag - BPS Bioscience
Recombinant human EIF2AK3 (a.a. 563-1115), with N-terminal GST-tag, expressed in E. coli cells.
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#12PERK/EIF2AK3 Antibody (24390-1-AP) - Thermo Fisher
Proteintech Anti-PERK/EIF2AK3 Polyclonal, Catalog # 24390-1-AP. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry ...
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#13EIF2AK3, encoding translation initiation factor 2-α kinase 3, is ...
EIF2AK3 has a role in the regulation of protein translation and is highly expressed in pancreatic islet cells. Our study indicates that EIF2AK3 functions in ...
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#14EIF2AK3 novel mutation in a child with early-onset diabetes ...
Wolcott-Rallison syndrome (WRS) is caused by a biallelic mutation in the gene encoding eukaryotic translation initiation factor 2-alpha kinase 3 ...
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#15Active EIF2AK3, Human Recombinant | P1737 | BioVision, Inc.
EIF2AK3 (Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3), also known as PERK, is a metabolic-stress sensing protein kinase that phosphorylates ...
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#16Gene: EIF2AK3 (ENSG00000172071) - Summary - Ensembl
Gene: EIF2AK3 ENSG00000172071 . twitter logo Twitter facebook logo Facebook email logo Email. Description. eukaryotic translation initiation factor 2 alpha ...
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#17PERK (EIF2AK3) (NM_004836) Human Tagged ORF Clone ...
Lenti ORF particles, EIF2AK3 (mGFP-tagged) - Human eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3), 200ul, >10^7 TU/mL.
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#18EIF2AK3 | Gene - VarSome
EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3), also known as PERK (protein kinase R-like endoplasmic reticulum kinase), was identified ...
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#19EIF2AK3 Gene - Ma'ayan Laboratory - Computational Systems ...
EIF2AK3 Gene. Name, eukaryotic translation initiation factor 2-alpha kinase 3. Description, The protein encoded by this gene phosphorylates the ...
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#20Anti-EIF2AK3 Antibody (HPA015737)
Rabbit Polyclonal Anti-EIF2AK3 Antibody against Human eukaryotic translation initiation factor 2-alpha kinase 3. Validated for Immunohistochemistry.
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#21PERK (EIF2AK3) Human Over-expression Lysates - Boster ...
PERK (EIF2AK3) Human Over-expression Lysates. Transient overexpression lysate of eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3).
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#22Human Gene EIF2AK3 (ENST00000303236.9) from ...
Description: Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3), transcript variant 1, mRNA. (from RefSeq NM_004836)
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#23The protein kinase PERK/EIF2AK3 regulates proinsulin ...
Loss-of-function mutations of the protein kinase PERK (EIF2AK3) in humans and mice cause permanent neonatal diabetes and severe proinsulin aggregation in ...
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#24eif2ak3 - ZFIN Gene
eif2ak3. ID: ZDB-GENE-050414-2; Name: eukaryotic translation initiation factor 2-alpha kinase 3; Symbol: eif2ak3 Nomenclature History; Previous Names.
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#25EIF2AK3 Rabbit pAb (A18196) - Polyclonal Antibodies
Western blot analysis of extracts of Mouse thymus, using EIF2AK3 antibody (A18196) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) ...
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#26anti-EIF2AK3 antibody :: Mouse EIF2AK3 Monoclonal Antibody
EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of ...
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#27eukaryotic translation initiation factor 2-alpha kinase 3; eif2ak3
604032 - EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 3; EIF2AK3 - PANCREATIC EIF2-ALPHA KINASE; PEK;; PERK - EIF2AK3.
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#28Wolcott-Rallison syndrome - Journal of Medical Genetics
10 Targeted disruption of the Eif2ak3 gene in mice also causes diabetes because of the accumulation of unfolded proteins triggering β cell apoptosis.1112 ...
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#29EIF2AK3 cDNA ORF clone, Homo sapiens(human) - GenScript
Next-day shipping cDNA ORF clones derived from EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 available at GenScript, starting from ...
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#30PERK/EIF2AK3 Research Areas - R&D Systems
PERK/EIF2AK3. PERK, a type 1 endoplasmic reticulum (ER) membrane kinase, mediates eIF2 alpha phosphorylation at Ser51 during the UPR (unfolded protein ...
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#31EIF2AK3 (eukaryotic translation initiation factor 2 alpha ...
EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol.
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#32Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3 ...
Human Eukaryotic Translation Initiation Factor 2 alpha Kinase 3 (EIF2AK3) Protein is a Human recombinant protein produced in E. coli.
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#33Identification of Two Novel Compound Heterozygous ...
Wolcott–Rallison syndrome (WRS, OMIM: 226980) is caused by an autosomal eukaryotic translation initiation factor 2-a kinase 3 (EIF2AK3) ...
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#34EIF2AK3 / PERK - LSBio
EIF2AK3 / PERK. eukaryotic translation initiation factor 2-alpha kinase 3. Phosphorylates the alpha subunit of eukaryotic ...
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#35EIF2AK3 Activator, CCT020312 - Calbiochem | 324879
EIF2AK3 Activator, CCT020312 - Calbiochem The EIF2AK3 Activator, CCT020312 modulates the biological activity of EIF2AK3. - Find MSDS or SDS, a COA, ...
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#36Plasmids related to Eif2ak3 - Addgene
ID Plasmid Gene/Insert PI 101793 pMXs‑mPERK‑FLAG‑IP Perk (Mus musculus) Oyadomari 58423 Flag_MmPERK_S503_N1114_pBabePuro PERK (Mus musculus) Ron 36954 pCMMP‑dnPERK‑IRES‑eGFP dnPERK (Homo sapiens) Sugden
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#37Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3 ELISA
This EIF2aK3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, ...
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#38Eif2ak3 General Information - Sino Biological
Eif2ak3 protein function. Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 ...
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#39EIF2AK3 [endoplasmic reticulum membrane] - Reactome ...
EIF2AK3 [endoplasmic reticulum membrane]. Stable Identifier. R-HSA-381046. Type. Protein [EntityWithAccessionedSequence]. Species. Homo sapiens. Compartment.
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#40Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 ...
Mouse Eif2ak3 Protein (raised in E. Coli) purified by multi-step, protein-specific process to ensure crystallization grade. State-of-the-art algorithm used for ...
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#41PERK/EIF2AK3 antibody (24390-1-AP) | Proteintech
Cited in 32 publications. PERK/EIF2AK3 antibody for IF, IHC, WB,ELISA and reacts with human.
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#42EIF2AK3, Active - Enzymes, Signaling Proteins, Extracellular ...
EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2) leading to its inactivation and a rapid reduction of ...
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#43pAV-EIF2AK3-shRNA, SH895936 | Vigene Biosciences
Four pre-designed shRNA constructs targeting eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) and one scrambled control.
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#44Anti-EIF2AK3, CT (Eukaryotic Translation Initiation Factor 2 ...
Buy Anti-EIF2AK3, CT (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PRKR-like Endoplasmic R, item number: E8949-17A-Biotin.200 from United ...
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#45EIF2AK3 - DECIPHER v11.9
EIF2AK3 2:88556741-88691518. Reverse strand gene: eukaryotic translation initiation factor 2 alpha kinase 3. Also known as: PERK, PEK, ENSG00000172071.
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#46EIF2AK3 - Orphanet
EIF2AK3 - eukaryotic translation initiation factor 2 alpha kinase 3. Synonym(s) : PEK, PERK; Previous symbols and names : _; Type : gene with protein ...
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#47EIF2AK3 Antibody (Phospho-Thr981) (OASG05793) - Aviva ...
EIF2AK3 Antibody (Phospho-Thr981) (OASG05793), Catalog OASG05793. Tested in IHC, IF, WB, ELISA applications. Reacts with Human, Mouse, Rat samples. Liquid.
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#48Genomic structure of the EIF2AK3 gene and polymorphisms...
Mutations in the EIF2AK3 gene underlie susceptibility to the Wolcott-Rallison syndrome, which is a monogenic disease associated with insulin-deficient neonatal ...
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#49- EIF2AK3 antibodies | Antibodypedia
EIF2AK3. gene product. PEK, PERK. The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, ...
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#50EIF2AK3 (Human) Cell-Based ELISA Kit - (KA3573) - Products
EIF2AK3 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of EIF2AK3 expression in cultured cells.
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#51EIF2AK3 related Antibodies, Proteins, cDNA and ELISA Kits
Eukaryotic translation initiation factor 2-alpha kinase 3 is a protein in humans that is encoded by EIF2AK3 gene. Metabolic-stress sensing protein kinase ...
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#52EIF2AK3 (3C3) Monoclonal Antibody
This EIF2AK3 antibody is generated from a mouse immunized with a recombinant protein conjugated synthetic peptide between 530-850 amino acids from human EIF2AK3 ...
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#53EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3
The Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and ...
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#54Invitrogen™ EIF2AK3 (PERK) Recombinant Human Protein
EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha. Manufacturer: Invitrogen™ PV5106.
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#55A novel EIF2AK3 mutation leading to Wolcott-Rallison ...
A novel EIF2AK3 mutation leading to Wolcott-Rallison syndrome in a Chinese child. Yanmei Sang, Min Liu, Wenli Yang, Jie Yan, Chengzhu and ...
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#56EIF2AK3 DepMap Gene Summary
EIF2AK3. eukaryotic translation initiation factor 2 alpha kinase 3. Location: Also known as: PERK, PEK. Ensembl: ENSG00000172071. NCBI Entrez Gene: 9451 ...
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#57eukaryotic translation initiation factor 2 alpha kinase 3
Human, 1, 1116, 2p11.2, EIF2AK3, eukaryotic translation initiation factor 2 alpha kinase 3. Mouse, 1, 1114, 6 C1, Eif2ak3, eukaryotic translation initiation ...
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#58EIF2AK3 ELISA Kits | Biocompare
The ELISA kits listed below target EIF2AK3, the symbol for the human gene, eukaryotic translation initiation factor 2 alpha kinase 3, ...
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#59Rat Eif2ak3(Eukaryotic translation initiation factor 2 ... - FN test
Product Name: Rat Eif2ak3(Eukaryotic translation initiation factor 2-alpha kinase 3) ELISA Kit; Catalogue No. ER1647; Alias: PERK ELISA Kit, ...
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#60Wolcott‑Rallison syndrome due to the same mutation in ...
Mutations in the eukaryotic translation initiation factor 2α kinase 3 (EIF2AK3), which is located at chromosome 2p12, are responsible for ...
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#61The EIF2AK3 gene homepage - Global Variome shared LOVD
Gene symbol, EIF2AK3. Gene name, eukaryotic translation initiation factor 2-alpha kinase 3. Chromosome, 2. Chromosomal band, p12.
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#62EIF2AK3 ELISA Kits - Creative Diagnostics
EIF2AK3. Full Name : eukaryotic translation initiation factor 2-alpha kinase 3. Keywords : EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase ...
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#63EIF2AK3 | Homo sapiens gene | Alliance of Genome Resources
Species: Homo sapiens; Symbol: EIF2AK3; Name: eukaryotic translation initiation factor 2 alpha kinase 3; Synonyms. DKFZp781H1925; eukaryotic translation ...
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#64Wolcott-Rallison syndrome (deletion/duplication analysis of ...
Wolcott-Rallison syndrome (deletion/duplication analysis of EIF2AK3 gene). EIF2AK3. Request Now. Methodology. Real-time quantitative PCR (RT-qPCR) ...
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#65Symbol report for EIF2AK3 - HUGO Gene Nomenclature ...
EIF2AK3. Approved name. eukaryotic translation initiation factor 2 alpha kinase 3. Locus type. gene with protein product. HGNC ID. HGNC:3255. Symbol status.
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#66Rat Eif2ak3(Eukaryotic translation initiation factor 2 ... - Ozyme
Product nameRat Eif2ak3(Eukaryotic translation initiation factor 2-alpha kinase 3) ELISA Kit Catalogue No.RTFI01385 AliasPERK,PRKR-like endoplasmic ...
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#67PERK (EIF2AK3) (NM_004836) Human 3' UTR Clone - AMSBIO
3`UTR clone of eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) for miRNA target validation.
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#68Identification of Novel Mutation in EIF2AK3 Gene as a Causal ...
WRS is caused by mutations in EIF2AK3 gene which encodes eukaryotic translation initiation factor 2a kinase 3, also known as pancreatic EIF2a kinase (PEK) and ...
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#69Human EIF2AK3 ELISA Kit (HUEB1168)- High Sensitivity
Human EIF2AK3 ELISA Kit from Assay Genie is a high quality, sensitive, ... Human Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) ELISA ...
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#70Gene | EIF2AK3 - Invitae
The EIF2AK3 gene is associated with autosomal recessive Wolcott-Rallison syndrome (WRS) (MedGen UID: 140926).
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#71Cellosaurus cell line HAP1 EIF2AK3 (-) 3 (CVCL_SL68)
Group: Haploid karyotype cell line. Knockout cell: Method=CRISPR/Cas9; HGNC; 3255; EIF2AK3. Omics: Deep RNAseq analysis. Derived from sampling ...
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#72EIF2AK3 Result Summary | BioGRID
Interactor Organism /; Chemical Type Evidence HSPA5 H. sapiens 5View RPN2 H. sapiens 4View CHRNA9 H. sapiens 3View
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#73Full article: Hepatitis C virus core protein activates autophagy ...
During ER stress, both the EIF2AK3 and ATF6 pathways of the unfolded protein response (UPR) were activated by HCV core protein. Then, these pathways upregulated ...
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#74Search results for EIF2AK3 - COSMIC
Your search term "EIF2AK3" was an exact match for the COSMIC gene EIF2AK3. A search of the whole COSMIC database returned results in 2 sections of the ...
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#75Human EIF2AK3 knockout HCT116 cell line (ab289137)
Although we aim to provide customers with a homozygous clone, feasibility will be dependent on the biology of the protein. Should only heterozygous edits be ...
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#76Mechanism-Based Screen for G1/S Checkpoint Activators ...
Significantly, EIF2AK3/PERK signalling has previously been linked to the resistance of cancer cells to multiple anticancer chemotherapeutic ...
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#77Re: EIF2AK3 Mutations in Patients with Wolcott-Rallison ...
They describe a homozygous missense serine 877 proline mutation of EIF2AK3 gene in a 5-year-old girl with WRS, and found that the mutated kinase ...
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#78EIF2AK3, encoding translation initiation factor 2-[alpha] kinase ...
EIF2AK3, encoding translation initiation factor 2-[alpha] kinase 3, is mutated in patients with Wolcott-Rallison syndrome ...
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#79The protein kinase PERK/EIF2AK3 ... - Archive ouverte HAL
PERK (EIF2AK3) is one of a small number of genes essential for maintaining glucose homeostasis. As such, PERK deficiency results in permanent ...
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#81PERK/EIF2AK3 抗体 | 小胞体ストレスセンサーとして知られる ...
PERK/EIF2AK3 抗体 | PERK/EIF2AK3 抗体（anti PERK/EIF2AK3 antibody）は、PERK/EIF2AK3 タンパク質を検出するウサギポリクローナル抗体です。…
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#82EIF2AK3, ID (PEK, WRS, PERK, DKFZp781H1925) (APC)
EIF2AK3, ID (PEK, WRS, PERK, DKFZp781H1925) (APC). 别名: PEK, WRS, PERK, DKFZp781H1925. 产品详情 国内授权经销商. 品牌: USBiological. 货号: 034988-APC
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#83Cancer: New Insights for the Healthcare Professional: 2012 ...
While EIF2AK3/PERK activation classically follows endoplasmic reticulum (ER) stress signalling that sets off a range of different cellular responses, ...
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#84CCT020312 is a Selective Activator of EIF2AK3/PERK
CCT020312, the G1/S checkpoint activator, is a selective EIF2AK3/PERK activator. CCT020312 elicits EIF2A phosphorylation in cells.
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#85How the unfolded protein response impacts fatty liver ...
Thus, when unfolded proteins accumulate, they are bound by BIP, releasing the three main UPR mediators that reside in the ER membrane. EIF2AK3 ( ...
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#86Systems biology analysis of human genomes points to ... - PNAS
由 V Aguiar-Pulido 著作 · 2021 — Herpes simplex virus 1 infection, 0.00685, HLA-A, EIF2AK3, EIF2AK4, ZNF439, CGAS, ZNF283, ... PERK regulates gene expression, 0.02427, EXOSC5, ASNS, EIF2AK3.
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#87Evolution of the Protein Synthesis Machinery and Its Regulation
... Julier C. EIF2AK3, encoding translation initiation factor 2-a kinase 3, ... study of EIF2AK3 mutations, and suggestion of genetic heterogeneity.
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#88The Genetics of Type 2 Diabetes and Related Traits: Biology, ...
It is the most common form of permanent neonatal diabetes in consanguineous families, caused by homozygous EIF2AK3 mutations (Dele ́pine et al. 2000).
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#89A Theranostic and Precision Medicine Approach for ...
... KCNH2 , HTR6 , DRD3 , HTR1A , CYP2D6 , HTR2C , ADRA1A , HRH1 MAP2K1 , MAP2K2 , MAPK1 , MAPK3 , RPS6KB1 , RB1 , ATK1 , EIF2AK3 , GNAQ , GNA11 HIST4H4 ...
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#90Pancreatic B Cell Biology in Health and Disease
4.2 EIF2AK3 mutations (Wolcott-Rallison syndrome) 4.2.1 Genetic alteration and clinical Mechanisms of β-cell demise in monogenic diabetes 191 4.1.2.
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#91Parkinsonism Beyond Parkinson's Disease - 第 56 頁 - Google 圖書結果
... interest in the genes coding for syntaxin-6 (STX6), myelin-associated oligodendrocyte basic protein (MOBP) and PERK (EIF2AK3) (Hoglinger et al., 2011).
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#92Genetic Diagnosis of Endocrine Disorders - 第 22 頁 - Google 圖書結果
... SYNTHESIS INS AD NDM: IUGR MODY10: rare GENETIC DISORDERS OF ER STRESS/CELL DEATH EIF2AK3 AR NDM: Wolcott–Rallison syndrome; epiphyseal dysplasia; ...
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