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#1Corepressor - an overview | ScienceDirect Topics
Corepressors are transcriptional regulators that are incapable of independent DNA binding, being recruited directly or indirectly by DNA-binding TFs to repress ...
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#2Sensors and signals: a coactivator/corepressor ... - PubMed
由 MG Rosenfeld 著作 · 2006 · 被引用 1052 次 — A decade of intensive investigation of coactivators and corepressors required for regulated actions of DNA-binding transcription factors has revealed a ...
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#3Corepressor SMRT is required to maintain Hox transcriptional ...
由 SH Hong 著作 · 2018 · 被引用 11 次 — In the classic model, corepressors bind to NRs in the absence of cognate ligands and dissociate from them upon ligand binding (5–7) providing a ...
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#4Sensors and signals: a coactivator ... - Genes & Development
A decade of intensive investigation of coactivators and corepressors required for regulated actions of DNA-binding transcription factors has revealed a network ...
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#5The transcriptional corepressor CtBP2 serves as a metabolite ...
The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis · Abstract · Introduction.
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#6transcription corepressor activity Gene Ontology Term (GO ...
Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure ...
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#7Corepressor Definition & Meaning - Merriam-Webster
The meaning of COREPRESSOR is a small molecule that activates a particular genetic repressor by combining with it.
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#8corepressor - 輔抑制物 - 國家教育研究院雙語詞彙
中國大陸譯名: 辅抑制物. 以corepressor 進行詞彙精確檢索結果. 出處/學術領域, 英文詞彙, 中文詞彙.
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#9Corepressor Definition & Meaning | Dictionary.com
Corepressor definition, a molecule that is capable of combining with a specific repressor molecule and activating it, thereby blocking gene transcription.
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#10New insights into the functions and regulation of the ...
Corepressors are large proteins that facilitate transcriptional repression through recruitment of histone-modifying enzymes.
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#11Role of the Nuclear Receptor Corepressor 1 (NCOR1) in ...
The transcriptional activity of these nuclear receptors is regulated by the nuclear receptor corepressors (NCORs), including NCOR1.
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#12Coactivator and Corepressor Regulation of the Agonist ...
To determine whether coactivators and corepressors have the capacity to modulate the relative agonist/antagonist activity of 4HT, ER-dependent gene ...
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#13Individual Subunits of the Ssn6-Tup11/12 Corepressor Are ...
ABSTRACT The Saccharomyces cerevisiae Ssn6 and Tup1 proteins form a corepressor complex that is recruited to target genes by DNA-bound ...
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#14A Corepressor/Coactivator Exchange Complex Required for ...
A Corepressor/Coactivator Exchange Complex Required for Transcriptional Activation by Nuclear Receptors and Other Regulated Transcription Factors. Valentina ...
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#15SEU - Transcriptional corepressor SEUSS - UniProt
DNA-binding adapter subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral ...
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#16QuickGO::Term GO:0003714
For example, one class of transcription corepressors modifies chromatin structure through ... RNA polymerase II transcription corepressor activity, related.
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#17Repression by the Arabidopsis TOPLESS corepressor ... - eLife
The TPL corepressor binds to the core mediator complex through MED21 to inhibit transcription while simultaneously priming repressed genes ...
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#18Myc represses transcription through recruitment of DNA ...
Here we show that Myc binds the corepressor Dnmt3a and associates with DNA methyltransferase activity in vivo. In cells with reduced Dnmt3a levels, ...
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#19corepressor - Wiktionary
corepressor (plural corepressors). (genetics) Any substance that reacts with a genetic repressor in order to activate it and decrease gene expression ...
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#20Corepressor Rcor1 is essential for murine erythropoiesis | Blood
Rcor1 represses expression of HSCs and myeloid genes during erythropoiesis, including Csf2rb, which is important in myeloid function. Abstract. The corepressor ...
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#21Role of the Transcriptional Corepressor Bcor in Embryonic ...
Bcor (BCL6 corepressor) is a widely expressed gene that is mutated in patients with X-linked Oculofaciocardiodental (OFCD) syndrome.
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#22N-CoR-HDAC Corepressor Complexes: Roles in ...
Many nuclear hormone receptors (NHRs) actively repress the expression of their primary response genes through the recruitment of transcriptional corepressor ...
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#23A Transcriptional Repressor and Corepressor Induced by the ...
In this study we show that IL-10 induces the expression of an ETS family transcriptional repressor, ETV3, and a helicase family corepressor, ...
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#24Structural Insights into Corepressor Recognition by Antagonist ...
Direct recruitment of transcriptional corepressors to estrogen receptors (ER) is thought to contribute to the tissue-specific effects of ...
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#25Corepressor-Dependent Silencing of Chromosomal Regions ...
The REST/NRSF COOH-terminal repression domain associates with at least one other factor, the transcriptional corepressor CoREST, characterized by two SWI3, ADA2 ...
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#26Phosphorylation of the nuclear receptor corepressor 1 by ...
Nuclear receptor corepressor 1 (NCoR1) is a transcriptional coregulator that has wide-ranging effects on gene expression patterns.
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#27Anti-Nuclear Receptor Corepressor NCoR antibody (ab58396)
Rabbit polyclonal Nuclear Receptor Corepressor NCoR antibody. Validated in WB, IHC and tested in Human. Cited in 5 publication(s).
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#28SUMOylation of the Corepressor N-CoR Modulates Its ...
In the absence of ligands the corepressor N-CoR mediates transcriptional repression by some nuclear hormone receptors. Several protein–protein interactions ...
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#29Subtype Specific Effects of Peroxisome Proliferator-Activated ...
Natural ligands for nuclear receptors are believed to activate gene transcription by causing dissociation of corepressors and promoting the ...
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#30More than a Corepressor: The Role of CoREST Proteins in ...
REST corepressor 1 (RCOR1) is a 12-exon gene located on chromosome 14 that encodes CoREST1, a 53-kDa protein composed of 485 amino acids ...
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#31REST corepressor 2_R (OZ554) (Plasmid #28079) - Addgene
This plasmid encodes a zinc finger array targeting half of a target sequence in the zebrafish gene REST corepressor 2 (see below).
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#32Ligand-Dependent Nuclear Receptor Corepressor LCoR ...
Ligand-Dependent Nuclear Receptor Corepressor. LCoR Functions by Histone Deacetylase-Dependent and -Independent Mechanisms al., 2000).
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#33A Nuclear Receptor Corepressor–Dependent Pathway ...
A Nuclear Receptor Corepressor–Dependent Pathway Mediates Suppression of Cytokine-Induced C-Reactive Protein Gene Expression by Liver X ...
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#34coactivator exchange. Corepressor (e.g., NCoR1/SMRT
Corepressor (e.g., NCoR1/SMRT; CoRep)/coactivator (CoAct) exchange results in the differential recruitment of enzymes acting on histone (white ovals) ...
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#35Corepressor definition and meaning | Collins English Dictionary
Corepressor definition: a small molecule that combines with, and activates , a repressor | Meaning, pronunciation, translations and examples.
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#36Mice lacking the transcriptional corepressor TIF1beta are ...
TIF1beta, a member of the transcriptional intermediary factor 1 family, has been reported to function as a corepressor for the large class ...
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#37A Conserved Role But Different Partners for the ...
Ttk88 uses the REST corepressor Drosophila CoREST to coordinately regulate a set of genes encoding the same neuronal hallmarks that are ...
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#38Terminology of Molecular Biology for corepressor - GenScript
corepressor. The metabolite that when bound to the repressor (of a repressible operon) forms a functional unit that can bind to its operator and block ...
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#39BCOR gene: MedlinePlus Genetics
A corepressor is a protein that cannot attach (bind) to DNA by itself, but interacts with other DNA-binding proteins to suppress the activity of certain genes.
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#40RB transcriptional corepressor 1 - Orphanet
RB1 - RB transcriptional corepressor 1 · Synonym(s) : PPP1R130, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, RB ...
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#41Hepatic nuclear corepressor 1 regulates cholesterol ... - JCI
Expression of a mutated nuclear corepressor 1 (NCoR1) that lacks 2 NR interacting domains (NCoRΔID) in the liver leads to elevated expression of genes ...
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#42Ligand-dependent corepressor acts as a novel corepressor of ...
Ligand-dependent corepressor (LCOR) was reported to function as a transcriptional corepressor in vitro. We found LCOR expression decreased ...
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#43Corepressor (genetics) - chemeurope.com
Corepressor (genetics) A corepressor is a protein that decreases gene expression by binding to a transcription factor which contains a DNA binding domain.
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#44The Role of Corepressors in Transcriptional Regulation by ...
This review focuses on how corepressors work together with nuclear receptors to repress gene transcription in the normal organism and on the ...
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#45Interplay of protein disorder in retinoic acid receptor ... - bioRxiv
Unliganded RAR exerts a strong repressive activity allowed by the recruitment of transcriptional corepressors and establishment of a corepressor ...
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#46Corepressor - Wikiwand
In the field of molecular biology, a corepressor is a molecule that represses the expression of genes.[1] In prokaryotes, corepressors are small molecules ...
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#47Difference Between Repressor and Corepressor
Corepressor is a protein that binds to the repressor protein and indirectly regulates gene expression. It is an effector molecule. They are able ...
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#48Digitala Vetenskapliga Arkivet - DIVA
The nuclear receptor corepressor (N-CoR) modulates basal and activated transcription of genes controlled by retinoic acid ...
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#49A corepressor participates in LexA ... - Microbiology Society
由 MA Peterson 著作 · 2020 · 被引用 8 次 — The DNA damage response of the multidrug-resistant pathogen Acinetobacter baumannii , which induces mutagenic UmuD′2C error-prone ...
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#50potential constitutive coactivation by corepressor splice variants
Corepressor /coactivator paradox: potential constitutive ... are thyroid hormone receptor coactivators that bind in the corepressor mode.
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#51Endocrine-Disrupting Chemicals: From Basic Research to ...
How Regulation of Coactivators and Corepressors Would Work to Limit Estrogenic ... in an estrogen-dependent increase in the expression of corepressor (e.g., ...
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#52Summary - Genetic Regulation
On the arrival and binding of the corepressor molecule the complex can act as a functional repressor and block the structural gene by binding at the ...
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#53FoxG1, a member of the forkhead family, is a corepressor of ...
FoxG1, a member of the forkhead family, is a corepressor of the androgen receptor-article.
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#54完整显示页面
Coactivator and corepressor complexes in nuclear receptor function-article. ... The nuclear receptor corepressors NCoR and SMRT decrease peroxisome ...
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#55Operon, Repressor, corepressor, inducer, auxiliary protein ...
Operon, Repressor, corepressor, inducer, auxiliary protein, Positive regulation, Negative regulation. Watch later. Share. Copy link.
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#56Male Reproductive Function - 第 74 頁 - Google 圖書結果
Coactivators and Corepressors. ... Upon ligand-binding, the corepressor is released, allowing interaction of the receptor with coactivator proteins.
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#57Tweaking a gene makes muscles twice as strong - Kurzweil AI
These either favor (coactivators) or inhibit (corepressors) ... By acting on this corepressor, it was possible to fundamentally change the ...
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#58Human Biochemistry - 第 483 頁 - Google 圖書結果
When the ligand binds, the corepressor proteins dissociate and coactivator proteins are recruited. Then, an array of other proteins forms a complex along ...
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#59AACR 2018 Proceedings: Abstracts 3028-5930 - Google 圖書結果
These analyses revealed enrichment for corepressors, e.g., DNMT1, ... To translate into therapy, we restored coactivator/corepressor balance by ...
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#60Therapeutic Resistance to Anti-hormonal Drugs in Breast ...
Many NRs repress gene expression in the unliganded state by recruiting transcriptional corepressors. In particular, the nuclear receptor corepressor (NCoR) ...
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#619AP Chapter 18 - Regulation of Gene Expression (detailed)
It requires tryptophan as a corepressor to assume its active form) p353,. A small molecule that cooperates with a repressor protein to switch an operon off.
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#62Transcription Regulators: Co-activators and Co-repressors
... receptor action: transcription coactivators and corepressors. ... A distinct mechanism for coactivator versus corepressor function by ...
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#63When did the tripartite treaty takes place? - Fleetserviceshocrv
... 1936 by Saburo Kurusu of Japan, Adolf Hitler of Germany, and Galeazzo Ciano (foreign minister) of … See also Is tryptophan a corepressor?
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#64Is ice age paleolithic? - Top 10 Wiki News
12 小時前 — Is tryptophan a corepressor? Next. On contacts what does bc mean? Be the first to comment. Leave a Reply ...
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