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#1Cohesin
The cohesin ring has many functions: 1. It is used to keep the sister chromatids connected with each other during metaphase ensuring that during mitosis (and ...
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#2Cohesin: functions beyond sister chromatid cohesion
Cohesin, a multi-protein complex conserved from yeast to human, plays a crucial role in this process by keeping the sister chromatids together ...
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#3The roles of cohesins in mitosis, meiosis, and human ...
These cohesin complexes are important for chromosome segregation, DNA repair, gene expression, development, and genome integrity. An external file that holds a ...
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#4Cohesin - an overview
Cohesin functions to tether chromosomal DNA during mitosis and meiosis to allow proper DNA segregation into daughter cells. It is a macromolecular complex that ...
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#5Full circle: a brief history of cohesin and the regulation of gene ...
Cohesin is essential for mediating chromatid cohesion during mitosis, for repair of double-strand DNA breaks, and for control of gene ...
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#6FACT mediates cohesin function on chromatin
Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction.
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#7Cohesins Hold the Sister Chromatids Together
Cohesin protein complexes are a molecular glue that holds two sister chromatids together. They play an important role both in mitosis and ...
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#8Binding, sliding, and function of cohesin during ...
The protein complex known as cohesin organizes eukaryotic genomes into structures that segregate faithfully between dividing cells. The complex ...
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#9Closing the cohesin ring: Structure and function of its Smc3 ...
A special complex, called cohesin, forms a ring made of three different proteins and functions to hold together the two sister DNA strands.
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#10Cohesin architecture and clustering in vivo
Evidence that the biological function of cohesin clustering is to maintain cohesion and RDN condensation. The requirement of Pds5p in the ...
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#11Cohesin and Beyond: Its Role in Health and Disease
In addition to this canonical role in chromosome segregation, cohesin is also needed for DNA repair, gene transcription regulation, and chromatin architecture.
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#12Cohesin: an emerging master regulator at the heart ...
Cohesins are DNA-binding ATPase ring-like complexes (Figure 1). Cohesin structure and putative functions of cohesin and its regulators are ...
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#13The multifaceted roles of cohesin in cancer
The cohesin complex controls faithful chromosome segregation by pairing sister chromatids after DNA replication until mitosis.
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#14Cohesin Function in Cohesion, Condensation, and DNA ...
Abstract. Cohesin tethers DNA to mediate sister chromatid cohesion, chromosome condensation, and DNA repair. How the cell regulates cohesin ...
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#15Cohesin's DNA Exit Gate Is Distinct from Its Entrance ...
these two cohesin subunits (Rowland et al., 2009). It has there- fore been suggested that a key function of Smc3 acetylation.
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#16Progresses on the structure and function of cohesin - 遗传
Cohesin is an evolutionarily conserved protein complex in eukaryotes. The four subunits of cohesin form a ring structure that plays an important role in ...
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#17A Conserved Domain in the Scc3 Subunit of Cohesin ...
Cohesin is a four-subunit complex that tethers distinct regions of chromatin either intra- or inter-molecularly. Cohesin is essential for mediating proper ...
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#18How do Cohesin and CTCF Fold DNA in Mammalian ...
In this talk, Dr. Peters presents evidence that cohesin also plays an important role in DNA folding and genome organization.
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#19Cohesin: Roles Beyond Sister Chromatid Cohesion? - YouTube
Cohesin also was shown to co-localize on chromosomes with a DNA binding ... They are also investigating the role of cohesin in structuring ...
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#20What is the role of cohesin complexes in species?
Role of cohesin: Cohesin mediates cohesion between replicated sister chromatids and is therefore essential for chromosome segregation in dividing cells. Mitosis ...
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#21Cohesin: Its Roles and Mechanisms
The cohesin complex is a major constituent of interphase and mitotic chromosomes. Apart from its role in mediating sister chromatid cohesion ...
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#22Cohesin: Its Roles and Mechanisms
The cohesin complex is a major constituent of interphase and mitotic chromosomes. Apart from its role in mediating sister chromatid cohesion, ...
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#23Importance of cohesin to yeasts' 3D chromosome structure
The 3D organization of chromosomes plays a role in many biological processes. The ring formed by the cohesin complex is an important regulator of this ...
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#24It's all in the numbers: Cohesin stoichiometry
Thus, cohesin function as a monomer or individual dimers may be sufficient for roles such as restricting the free diffusion of chromatin, ...
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#25Gene group: Cohesin complex
Cohesin : functions beyond sister chromatid cohesion. Mehta GD et al. FEBS Lett 2013 Aug;587(15)2299-2312.
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#26Cohesin
Technological advancements have discovered myriad functions of cohesin beyond its role in sister chromatid cohesion (SCC), such as transcription ...
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#27In vivo analysis of cohesin architecture using FRET in the ...
The other Smc complexes are condensin, required for chromosome compaction during mitosis, and an Smc5/Smc6 containing complex with a role in DNA repair. Smc ...
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#28Role in Chromosome Segregation/Repair and Potential in ...
The canonical cohesin complex consists in four subunits named SMC1, SMC3 (Structural Maintenance of Chromosomes) and SCC1, SCC3 (Sister Chromatid Cohesion). Two ...
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#29Condensins and cohesins – one of these things is not like ...
Here, cohesins produce loops that establish genome-wide organization and impact transcription states within the nucleus. The role of cohesins is even.
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#30Cohesin organization, dynamics, and subdomain functions ...
Cohesin is a heteropentameric protein complex that contributes to various aspects of chromosome structure and function, such as sister chromatid cohesion, ...
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#31Meiosis-Specific Cohesin Complexes Display Distinct and ...
Cohesin is a chromosome-associated SMC‒kleisin complex that mediates sister chromatid cohesion, recombination, and most chromosomal processes ...
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#32Cohesin proteins and human development
Cohesin proteins play a critical role in cell division during mitosis. After the chromosomes are replicated, they line up along the middle of ...
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#33Distinct Functions of Human Cohesin-SA1 and ...
The primary function of cohesin is to mediate genome-wide sister chromatid cohesion in a cell cycle-regulated manner to en-.
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#34Many functions of the meiotic cohesin
Though cohesins localize to chromosome axes (see later), their role in axis formation was negated since (among others) chromosomes without ...
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#35Analysis of Cohesin Function in Gene Regulation and ...
To study cohesin's role in gene expression and chromatin organization, it is necessary to avoid secondary effects due to disruption of vital cohesin functions ...
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#36Role of Cohesin-Resolving Protease, Separase, In ...
A recent study suggests a new role of Cohesin proteins in gene expression and development with implications in hematopoiesis.
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#37Structural Insights into Ring Formation of Cohesin and ...
Cohesin facilitates sister chromatid cohesion through the formation of a large ring structure that encircles DNA. Its function relies on two structural ...
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#38Chromosome Instability and Dynamics Laboratory
Cohesin is best known for its role in sister chromatid cohesion, and has been proven essential for their equal segregation during mitosis and meiosis. In ...
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#39Cohesin loading and sliding | Journal of Cell Science
Cohesin is best known as a crucial component of chromosomal stability. Composed of several essential subunits in budding yeast, cohesin ...
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#40Study of cohesin functions in Cornelia de Lange Syndrome
Methodology: Our hypothesis is that the CdLS phenotypes are due to alterations in the putative cohesin complex role in gene expression. Commonly, cohesin ...
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#41Study sheds new light on mechanisms of cohesin function ...
Ana Losada, from the Spanish National Cancer Research Centre (CNIO), is the scientist who identified cohesin in vertebrates, a protein that ...
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#42Cohesin dynamic association to chromatin and interfacing ...
discovered requirement for cohesin function to promote efficient fork progression upon stalling by the presence of damaged DNA templates, dNTPs depletion or ...
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#43Condensin and cohesin display different arm ...
In eukaryotes, two different SMC protein complexes, condensin and cohesin, ... Functional implications for the actions of condensin and cohesin.
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#44Cohesin subunit scc-3 - Caenorhabditis elegans | UniProtKB
Function. function. Component of the cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication (PubMed: ...
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#45Biochemical reconstitution of topological DNA binding by ...
The cohesin complex consists of at least four subunits that together form a large proteinaceous ring. It is thought that cohesin holds together sister ...
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#46An update on cohesin function as a 'molecular glue' on ...
Apart from its role in holding chromosomes together in mito- sis, new roles for cohesin in DNA damage repair, gene regulation and spindle pole ...
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#47The cell. More information. COHESINS and CONDENSINS
Cohesin function during mitosis. Cohesins keep sister chromatids attached from prophase to anaphase. M-CdK starts three molecular processes ...
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#48Gene Regulation by Cohesin in Cancer: Is the Ring an ...
Cohesin's function in the cell cycle. Cohesin is loaded onto chromosomes before S-phase and holds sister chromatids together throughout G2-phase until their ...
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#49Topological in vitro loading of the budding yeast cohesin ...
The latter play their role during cohesin loading onto chromatin in vivo (Chao et al, 2015). Following topological loading onto DNA, fission ...
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#50Researchers unravel role of cohesins in embryonic stem ...
Scientists have been working for a long time to understand the role played by cohesin during meiotic cell division. Cohesins are important ...
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#51Evidence of a Transcriptional Co-activator Function of ...
Although cohesins. Smc1, Smc3, and Scc1/Rad21 are involved in chromatid cohesion and other cellular processes, little is known about the other ...
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#52The interplay of cohesin and DNA replication in sister ...
Among these, we identify a role for MMS22L-TONSL in sister chromatid cohesion establishment. Furthermore, we identify a novel regulator of ...
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#53Cohesin
Cohesin is a protein complex that mediates sister chromatid cohesion, homologous recombination, and DNA looping. Cohesin is formed of SMC3, SMC1, ...
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#54Recent advances in cohesin biology
A protein complex called cohesin is responsible for holding the sister chromatids together and serves important roles in chromosome condensation ...
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#55Sister chromatid cohesion and separation
The concerted actions of protein kinases and Wapl open cohesin rings in a ... We found that this has three functional consequences: It renders separase ...
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#56Professor Mike Eccles
Unveiling the hidden players: The crucial role of transposable elements in the placenta and their potential contribution to pre-eclampsia. Placenta.
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#57Cell Cycle and Cell Division Class 11 Notes CBSE Biology ...
This chapter comes under Unit III- Cell: Structure-Function which has a weightage of ... The cohesin (protein complex) degrades from the chromosome arms and ...
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#58Protein Complexes that Modify Chromatin
Cohesin proteins are thought to assist formation of stable ... Psc3 cohesin subunit suggest that Swi6 functions directly to recruit cohesin (NONAKA et al.
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#59Issues in Genetic Medicine: 2011 Edition - Google 圖書結果
While both Smc1p and Smc3p ATP binding and hydrolysis are essential for cohesin function in vivo, little is known about how this core enzymatic activity is ...
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#60Advances in Microtubule-Organizing Center Research and ...
Here we show that the cohesin Rad21 is required for centrosome integrity independently of its role as a chromosomal cohesin,” wrote N.A. Beauchene and ...
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#61What Is A G2 Pill
-A protein that destroys cohesin through its protease activity. ... also known as G2/M-phase checkpoint, has the function of preventing cells with damaged ...
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#62Germ Cell Development and Reproductive Aging
Two rare loss-of-function variants in the STAG3 gene leading to primary ovarian ... The cohesin subunit RAD21L functions in meiotic synapsis and exhibits ...
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#63International Review of Cytology - 第 156 頁 - Google 圖書結果
This localization is in accordance with the prominent role of cohesion in centromere coorientation. Two components of the cohesin complex, Smc1p and Smc3p, ...
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#64Chromosome Structures: Advances in Research and Application: ...
... of chromatin organization mediated by CTCF and cohesin.' “CTCF sites are abundant in the genomes of diverse species but their function is enigmatic.
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#65Probing the Ubiquitin Landscape - 第 88 頁 - Google 圖書結果
The canonical function of Importantly, polySUMOylation of the two cohesin-related SMC complexes, condensin and SMC5/6 is also controlled by SENP6.
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#66無題
Cohesin cancer compatibility. Movimiento afroecuatoriano en el ... $sce.trustashtml is not a function. ... Function of the endocrine system yahoo games.
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