Perjumpaan pertama telah diadakan hari ini untuk Special Task Force Covid-19 di peringkat negeri Johor. Turut hadir bersama YAB Dato’ Haji Hasni bin Mohammad, Menteri Besar Johor, YB Dato’ Haji Azmi bin Rohani, Setiausaha Kerajaan Johor, YB Dato’ Haji Mohd Noh Bin Ibrahim, Timbalan Setiausaha Kerajaan Johor (Pengurusan), YB Tuan Vidyananthan A/L Ramanadhan, EXCO Kesihatan dan Alam Sekitar, YB Dato’ Dr. Aman bin Rabu, Pengarah Jabatan Kesihatan Negeri Johor dan pakar-pakar kesihatan dan pengurusan pandemik.

Special Task Force Covid-19 berperanan untuk memantau dan memperbaiki proses yang digunakan bagi sistem menyaring, mengasingkan, mengawasi, dan merawat pesakit Covid-19 agar keadaan wabak adalah sentiasa dalam kawalan. Pengesanan kontak perlu dipercepatkan supaya ia dilakukan dalam jangka masa 24 hingga 48 jam, dan kadar vaksinasi juga perlu dipertingkatkan.

Johor perlu bersedia untuk transisi dari situasi pandemik kepada endemik. Saya yakin dengan para anggota Task Force ini yang dipilih secara inklusif dan melibatkan pelbagai agensi kerajaan, pakar-pakar dari universiti, swasta, ATM, dan NGO, Johor akan dapat melawan wabak Covid-19 dengan lebih berkesan dan kes positif akan mula menurun melalui langkah kesihatan awam yang efektif dan penggunaan teknologi terkini.

DYAM Mejar Jeneral Tunku Ismail Ibni Sultan Ibrahim, Tunku Mahkota Johor

———

The first meeting for the Special Task Force Covid-19 at the Johor state level was held today. Also present were Menteri Besar of Johor YAB Dato' Haji Hasni bin Mohammad, Johor State Secretary YB Dato' Haji Azmi bin Rohani, Johor Deputy State Secretary (Management) YB Dato' Haji Mohd Noh Bin Ibrahim, Health and Environment EXCO YB Tuan Vidyananthan A/L Ramanadhan, Johor Health Department Director YB Dato' Dr. Aman bin Rabu as well as health and pandemic management experts.

The Covid-19 Special Task Force will monitor and improve processes used for the screening, isolating, monitoring and treating system of Covid-19 patients to ensure the outbreak's situation is always under control. Contact tracing needs to be accelerated so that it is done within 24 to 48 hours, and vaccination rates must also be increased.

Johor needs to be prepared for the transition from a pandemic to an endemic. I am confident that the selected members of this Task Force, which are inclusive and involving various government agencies, experts from universities, private sectors, Malaysian Armed Forces, and NGOs in Johor, will be able to fight the Covid-19 pandemic more effectively and positive cases will begin to decline through effective public health measures and the use of the latest technology.

HRH Major General Tunku Ismail Ibni Sultan Ibrahim, Crown Prince of Johor

Inspired by COVID-19, chapter 4 of #AI2041, “Contactless Love” imagines new variants of disease cropping up even once everyone is vaccinated. In 2041 people have learned how to co-exist with the virus, aided by constantly evolving therapies and household robots that reduce person-to-person contact. Fearful of disease, however, the heroine of this story closes herself off from the world, setting up a conflict between pursuing love and avoiding human contact. The story reveals how COVID-19 has accelerated AI-enabled drug discovery and precision medicine. www.ai2041.com

打完疫苗後，到底要不要驗抗體？

最近好像有在討論打完疫苗驗抗體的事情。我們是大規模施打疫苗後，全台前幾家開始檢驗中和抗體的院所，有一些經驗與想法，跟大家分享。

1. 不要太早驗。如果疫苗的設定是打兩劑的，請在第二劑後 2-4 週再去驗。第一劑反應不佳的，有不少打完第二劑後會衝得爆高。

打完一劑去檢驗，意義有限。抗體不高，甚至沒抗體也不代表第二劑後無法產生抗體。

以我父親為例。他打完第一劑後，中和抗體是偵測不到的。
但打完第二劑兩週後，衝高得相當不錯。（這我就比較安心了）

2. 如果是同一種疫苗。抗體越高，的確是保護力越好無誤。

3. 不同機器，數字不可以、不可以、不可以直接比較。同一個樣本，這台機器數據 5000，另一台可能只是 50。因為單位不同。

例如：我喝了 5 水。--> 這句話毫無意義
Ａ：我喝了 5 (公升)的水
Ｂ：我喝了 500 （毫升）的水

誰喝的水多？ 其實是Ａ。

4. 抗體不等於中和抗體。中和抗體才是有用的抗體。兩者相關。但每個人的相關性又不同。

有的人抗體很高，但中和抗體不高
有的人抗體不高，但中和抗體很高

不過，整體而言，是正相關無誤，但個體差異很大。也許有人相關係數是 0.9，有人是 0.5 ，類似這樣。

6. 甲牌一定比乙牌抗體高嗎？未必喔
大家愛講莫德納/BNT抗體很高，以作為選擇的依據

雖說“平均值”而言如此

但大家都知道“平均值”的問題所在。
舉例來說：對個人而言，財富“平均值”意義就不大
任何人跟比爾蓋茲平均後，都是世界富豪。但這顯然沒意義啊。

以我檢驗的中和抗體數據來說。
有的 2 ＡＺ抗體，比2劑ＢＮＴ（在國外施打的），2劑莫德納，或者是混打者還要高！

甚至有人打完一劑ＡＺ後，抗體直逼兩劑 mRNA 疫苗的量

一切看個人體質（造化），如果打到剛好適合你的，就是最好（但在打之前，不會有人知道就是了）。

7. 不同疫苗，數字不可以“直接”比較。
以國外大規模 moderna/AZ 的比較來說。
在同樣的保護力下，ＡＺ疫苗需要的抗體普遍較低。

例如：90% 保護力下，ＡＺ抗體可能只需要 100。而 moderna 在達到同樣的保護力水準時，需要 300，才是 90%。
（數據是舉例，原始數據如下，有興趣請自行服用）
然後抗體數據，跟中和抗體數據又不可以劃上等號

Pseudovirus neutralization results can also be compared using calibrated ID50 titers, where estimated ChAdOx1 nCoV-19 vaccine efficacy was 70% and 90% at cID50 titer of 4 (NC, 12) and 64 (20, NC), compared to the COVE trial results
at cID50 titer of 4 (< LOD = 2.42, 22) and 83 (16, 188)
Together with evidence from other studies, the current results support that neutralization titer is a potential surrogate marker for mRNA-1273 vaccination against COVID-19 that can be considered as a primary endpoint for basing certain accelerated approval decisions

附上ＡＺ原始牛津團隊的數據表，供大家參考

這篇牽扯到很多很新的研究，有興趣的歡迎來當面討論 ＾＾

＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝
謝絕各界媒體捧有轉載喔～～感謝感謝

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The above price is for 1 session of Korean V-Face Hifu
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Key Benefits (Profhilo)

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