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[爆卦]ABCA1是什麼？優點缺點精華區懶人包
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#1ABCA1 - Wikipedia
ATP-binding cassette transporter ABCA1 also known as the cholesterol efflux regulatory protein (CERP) is a protein which in humans is encoded by the ABCA1 ...
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#2ABCA1 gene: MedlinePlus Genetics
The ABCA1 gene belongs to a group of genes called the ATP-binding cassette family, which provides instructions for making proteins that transport molecules ...
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#3ABCA1 ATP binding cassette subfamily A member 1 [ (human)]
ABCA1 is the major mediator of human macrophage cholesterol efflux to HDL, demonstrating most marked efficiency with small, dense HDL ...
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#4ABCA1 Gene - ATP Binding Cassette Subfamily A Member 1
ABCA1 (ATP Binding Cassette Subfamily A Member 1) is a Protein Coding gene. Diseases associated with ABCA1 include Tangier Disease and ...
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#5Regulation of ATP binding cassette transporter A1 (ABCA1 ...
ATP binding cassette transporter A1 (ABCA1) is a transmembrane transporter protein ubiquitously expressed in human tissue, and found in ...
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#6Phospholipid-transporting ATPase ABCA1 - UniProt
Disease descriptionAn autosomal dominant disorder characterized by decreased plasma high density lipoproteins, moderately low HDL cholesterol, a reduction in ...
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#7ABCA1 - an overview | ScienceDirect Topics
ABCA1 is the cholesterol/phospholipid efflux protein that is defective in patients with Tangier disease and familial HDL deficiency. These patients cannot form ...
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#8ATP-BINDING CASSETTE, SUBFAMILY A, MEMBER 1; ABCA1
ABCA1 functions as a cholesterol efflux pump in the cellular lipid removal pathway. ▻ Cloning and Expression.
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#9Cholesterol efflux mechanism revealed by structural analysis ...
ATP-binding cassette transporter A1 (ABCA1) utilizes energy derived from ATP hydrolysis to export cholesterol and phospholipids from ...
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#10Frontiers | Elucidating the Structural Features of ABCA1 in its ...
ATP Binding Cassette Transporter A1 (ABCA1) plays an integral part in Reverse Cholesterol Transport (RCT) and is critical for maintaining ...
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#11Metabolomic analysis of a selective ABCA1 inducer in ...
Anticipating that many beneficial and detrimental effects of LXR agonists are mediated by ABCA1 and SREPB1c expression, respectively, ...
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#12Abca1 MGI Mouse Gene Detail - MGI:99607 - ATP-binding ...
View mouse Abca1 Chr4:53030787-53159895 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.
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#13ABCA1 protein expression summary
Gene name, ABCA1 (HGNC Symbol). Synonyms, ABC1, HDLDT1, TGD. Description, ATP binding cassette subfamily A member 1 (HGNC Symbol). Chromosome, 9.
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#14ABCA1 | ABCA subfamily - IUPHAR/BPS Guide to ...
ABCA1 - ABCA subfamily. Detailed annotation on the structure, function, physiology, pharmacology and clinical relevance of drug targets.
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#15ABCA1 Antibody - BSA Free (NB400-105) - Novus Biologicals
ABCA1 is involved in the regulation of apolipoprotein AI (apoAI)-mediated cholesterol efflux and high-density lipoproteins (HDL) metabolism (1). In the brain, ...
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#16Structure of the Human Lipid Exporter ABCA1
ABCA1, an ATP-binding cassette (ABC) subfamily A exporter, mediates the cellular efflux of phospho- lipids and cholesterol to the ...
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#17ABCA1 Antibody (PA1-16789) - Thermo Fisher
Invitrogen Anti-ABCA1 Polyclonal, Catalog # PA1-16789. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF), Immunohistochemistry (Frozen) (IHC (F)), ...
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#18HDL Apolipoproteins and ABCA1 - AHA Journals
Thus, the apolipoprotein/ABCA1 pathway efficiently clears cells of excess cholesterol that would otherwise accumulate as intracellular lipid droplets. ABCA1 ...
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#19ABCA1 Products - R&D Systems
ABCA1 (ATP-binding cassette, subfamily A member 1; also cholesterol efflux regulatory protein) is a 240-280 kDa member of the ABCA family, ABC transporter ...
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#20ABCA1 (ATP-binding cassette transporter) Antibody - Neuromics
By Western blot mouse anti-ABCA1 (MO13101; clone HJ1) recognizes rat (left image), mouse (right image) and to a lesser extent human (left image) ABCA1.
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#21High Density Lipoproteins: From Biological Understanding to ...
of ABCA1 to exit the ER (Singaraja et al. 2006). In the Golgi compartment, ABCA1 undergoes palmitoylation at cysteine residues 3, 23, 1110, and 1111 by the ...
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#22TNFα induces ABCA1 through NF-κB in macrophages ... - PNAS
Macrophage cholesterol uptake induces ATP-binding cassette (ABC) transporter ABCA1 promoting cholesterol efflux to apolipoprotein A-I and reducing ...
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#23ABCA1 - DocCheck Flexikon
ABCA1 is a membrane protein which transports cholesterol from the cytosol to the cell surface as a part of the reverse cholesterol transport (cholesterol ...
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#24Hsap\ABCA1 - FlyBase Gene Report
Hsap\ABCA1. Species. H. sapiens. Name. ATP binding cassette subfamily A member 1. Annotation Symbol. Feature Type. engineered_foreign_gene. FlyBase ID.
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#25Human Gene ABCA1 (uc004bcl.3) - UCSC Genome Browser
Description: Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1), mRNA. RefSeq Summary (NM_005502): The membrane-associated protein ...
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#26The Role of the ATP-Binding Cassette A1 (ABCA1) in ... - MDPI
One of several proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 (ABCA1), a transmembrane protein widely ...
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#27ABCA1, from pathology to membrane function | SpringerLink
ABCA1 acts as a lipid translocator and, as such, modulates the lipid architecture at the membrane and its physicochemical properties. Lipid ...
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#28ABCA1 Gene - Ma'ayan Laboratory - Computational Systems ...
tissues with high or low expression of ABCA1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset ...
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#29ATP-binding Cassette Transporter A1 (ABCA1) Functions as a ...
ABCA1, an ATP-binding cassette transporter mutated in Tangier disease, promotes cellular phospholipid and cholesterol efflux by loading free apoA-I with ...
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#30ABCA1 - LSBio
ABCA1 (ATP-binding Cassette, Sub-family A, Member 1), also known as ABC1 (ABC Transporter 1) or CERP (Cholesterol efflux regulatory ...
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#31ATP-binding cassette transporter A1 (ABCA1) affects total ...
Methods: ABCA1-deficient mice (ABCA1−/− ) and wild-type mice were compared for different aspects of sterol metabolism. Intestinal cholesterol absorption was ...
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#32The regulatory domains of the lipid exporter ABCA1 form ...
ABCA1 and ABCA4 are enigmatic because they transport substrates in opposite directions yet share >50% amino acid identity.
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#33Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol ...
ABCA1 is ubiquitously expressed, particularly at high levels in liver, small intestine, macrophages, adrenal glands, lungs, placenta, and fetal ...
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#34Regulation of ABCA1 expression and cholesterol efflux during ...
sette transporter A1 (ABCA1). It was described originally that a mutation in the abc1 gene was responsible for the drastic reduction in HDL-cholesterol in ...
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#35Significance of ABCA1 in human carotid atherosclerotic plaques
The ATP-binding cassette transporter A1 (ABCA1) is an important effector in the regulation of cholesterol efflux from cells.
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#36Effects of ABCA1 gene polymorphisms on risk factors ...
ATP binding cassette transporter A1 (ABCA1) plays an important role in lipid metabolism and is involved in reverse cholesterol transport (RCT) and thus has ...
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#37ABCA1 Membrane Protein Introduction - Creative Biolabs
ABCA1, encoded by ABCA1 gene, belongs to an ATP-binding cassette (ABC) transporters superfamily which transport various molecules across extra- and ...
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#38Transmembrane Dynamics of Lipids - 第 363 頁 - Google 圖書結果
Collectively, these data highlight that ABCA1 expressed in liver and in macrophage exert complementary roles in the overall cholesterol trafficking in the ...
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#39Intestinal ABCA1 directly contributes to HDL biogenesis in vivo
Plasma HDL cholesterol levels are inversely related to risk for atherosclerosis. The ATP-binding cassette, subfamily A, member 1 (ABCA1) mediates the ...
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#40A novel missense mutation in ABCA1 results in altered protein ...
Mutations in ABCA1 underlie Tangier disease (TD) and familial high-density lipoprotein (HDL) deficiency, 10-13 conditions characterized by the ...
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#41Functional Loss of ABCA1 in Mice Causes Severe Placental ...
Both diseases are characterized by the lowering or lack of high-density lipoprotein cholesterol (HDL-C) and low serum cholesterol. The murine ABCA1−/− ...
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#425XJY: Cryo-EM structure of human ABCA1 - RCSB PDB
ABCA1, an ATP-binding cassette (ABC) subfamily A exporter, mediates the cellular efflux of phospholipids and cholesterol to the ...
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#43Elucidating the structural features of ABCA1 in its ... - bioRxiv
ATP Binding Cassette Transporter A1 (ABCA1) plays an integral part in Reverse Cholesterol Transport (RCT) and is critical for maintaining ...
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#44Mouse ATP Binding Cassette Transporter A1 (ABCA1) Protein
Recombinant ATP Binding Cassette Transporter A1 (ABCA1) is a recombinant Mouse protein produced in E. coli using Prokaryotic expression.
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#45ABCA1 contributes to macrophage deposition of extracellular ...
ABCA1 and ABCG1 both function in mediating cellular cholesterol efflux and contributing to reverse cholesterol transport (3, 4, 5).
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#46Definition of ABCA1 pathway - NCI Dictionary of Cancer Terms
Describes a group of proteins in a cell that work together to help remove extra cholesterol and certain fats from tissue in the body. Changes in the ABCA1 ...
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#47ATP Binding Cassette Transporter A1 CLIA | stjohnslabs
This mouse ABCA1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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#48Liver ABCA1, Lipoprotein Metabolism and Atherosclerosis
ATP binding cassette transporter A1 (ABCA1) effluxes phospholipid and free cholesterol from cells, forming nascent high density lipoproteins (HDLs).
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#49Elevated Lipoprotein(a) Levels Lower ABCA1 Cholesterol ...
Elevated serum lipoprotein(a) [Lp(a)] levels are associated with increased cardiovascular disease risk. ABCA1-mediated cholesterol efflux from macrophages ...
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#50Encoding Visual Features by Parallel Ganglion Cell Initiated ...
(B) Western blots showing the dose-dependent decrease in ABCA1 expression in HEK293 cells after TBK1 overexpression. (C) Statistical analysis of the data ...
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#51PPARγ-LXRα-ABCA1信号通路在动脉粥样硬化防治研究新进展
其中细胞内胆固醇代谢失衡形成泡沫细胞是AS发生和发展的关键步骤。PPARγ-LXRα-ABCA1信号通路对胆固醇的代谢、炎症反应有重要影响，在维持胆固醇平衡、抑制 ...
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#52Cholesterol transporter ATP-binding cassette A1 (ABCA1) is ...
Cholesterol transporter ATP-binding cassette A1 (ABCA1) is elevated in prion disease and affects PrPC and PrPSc concentrations in cultured cells Free.
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#53GPS2 is involved in LPS-induced Abca1 expression and ...
C ) Western blot analysis of ABCA1, GPS2, and b-actin in WT and KO RAW cells treated with LPS. D) Cholesterol efflux analysis in LPS-treated WT and Gps2 KO ...
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#54Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR ...
Activation of NR1H2,3 induces expression of ATP-binding cassette transporter A1 (ABCA1), which acts in the plasma membrane and endosomal system to promote ...
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#55Hesperetin Upregulates ABCA1 Expression and Promotes ...
ABCA1, a member of the ATP-binding cassette transporter family, regulates high-density lipoprotein (HDL) metabolism and cholesterol ...
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#56ABCA1 cdna clone-BC141816 - MyBioSource
ABCA1 : an ATP-binding cassette (ABC) transporter that regulates cholesterol homeostasis and insulin secretion in beta-cells, and protects against cardiovascular ...
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#57ABCA1 expression and statins: inhibitory effect in peripheral ...
The ATP-binding cassette transporter A1 (ABCA1) has an essential role in the formation of nascent high-density lipoprotein particles and ...
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#58ABCA1 cDNA Clones Research Reagents | Sino Biological
We have professional and advanced research and production capacity for ABCA1 reagents production, including cDNA Clones,etc. All ABCA1 products are produced ...
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#59ABCA1: An Example of the Effect of Cholesterol on Exocytosis
Like us on Facebook: https://www.facebook.com/pages/Stroma-Studios/290868104261105?sk=wallThe transporter protein ABCA1 (shown in red) is ...
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#60ABCA1 (ATP binding cassette subfamily A member 1) | Gene ...
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.
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#61ABCA1 - Genomics England PanelApp
Red ABCA1 in Familial hypercholesterolaemia. Level 3: Arteriopathies Level 2: Cardiovascular disorders. Version 1.28. review, Not set ...
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#62Is the effect of rosuvastatin on ABCA1 transporter level direct ...
ABCA1 is an important modulator of HDL-C levels. ... the ATP binding cassette transporters ABCA1 promote cholesterol efflux from macrophages ...
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#63In Vivo Inflammation Does Not Impair ABCA1-Mediated ...
THP1 cells, a macrophage cell line expressing ABCG1, ABCA1, and SR-B1, were used to reflect total in vivo cholesterol efflux. These studies may imply that ...
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#64Anti-ABCA1 affinity isolated antibody ABC-1 - Sigma-Aldrich
Anti-ABCA1 affinity isolated antibody; Synonyms: CERP,HDLDT1,ABC1,ABC-1,TGD; find Sigma-Aldrich-SAB4301792 MSDS, related peer-reviewed papers, ...
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#65α1-Syntrophin Modulates Turnover of ABCA1 - X-MOL
ABCA1 (ATP-binding cassette transporter A1) mediates the release of cellular cholesterol and phospholipid to form high density lipoprotein.
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#66ABCA1 - 转化医学网
概述ABCA1为ATP-binding cassette transporterA1，三磷酸腺苷结合盒转运体A1编码基因。该蛋白以ATP为能源，促进细胞内游离胆固醇和磷脂的流出，在胆固醇逆转运(RCT) ...
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#67Exome sequencing identifies rare damaging variants in the ...
Exome sequencing identifies rare damaging variants in the ATP8B4 and ABCA1 genes as novel risk factors for Alzheimer's Disease.
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#68Screening for functional sequence variations and mutations in ...
The ABCA1 gene contains 50 exons and codes for a 2261-amino acid long membrane protein that facilitates phospholipid and cholesterol transport. Several ...
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#69"Wild type and Tangier disease ABCA1 mutants modulate ...
ABCA1 also regulates Aβ metabolism in the brain although its direct impact on AβPP remains an open question. Here we assessed the capacity of three ABCA1 ...
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#70Contribution of APOA5, APOC3, CETP, ABCA1 and SIK3 ...
Contribution of APOA5, APOC3, CETP, ABCA1 and SIK3 genetic variants to hypertriglyceridemia development in Mexican HIV-patients receiving antiretroviral ...
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#71Full Text Journal Article: The role of the ABCA1 transporter ...
We investigated the role of ABCA1-mediated cholesterol efflux in Dutch subjects suffering from FHA. Eighty-eight subjects (mean HDL cholesterol levels 0.63 +/- ...
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#72ABCA1 | The University of Chicago Genetic Services
ABCA1. Dyslipidemia Panel · University of Chicago. Phone: 773.834.0555; Fax: 773.702.9130; Toll free: 888.824.3637; Follow us on:.
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#73FAM110A Gene - Somatic Mutations in Cancer - COSMIC
FAM110A Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, FAM110A Genome Browser, FAM110A References.
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#74ABCA1 promoter luciferase reporter (P2 fragment) Sequences
ABCA1 promoter luciferase reporter (P2 fragment) Sequences (2). Addgene Sequences: Full (1). Depositing Scientist Sequences: Partial (1) ...
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#75[PDF] Pivotal role of ABCA1 in reverse cholesterol transport ...
The identification of mutations in ABCA1 in patients with Tangier disease and familial HDL deficiency demonstrated that inadequate transport ...
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#76Carriers of Loss-of-Function Mutations in ABCA1 Display ...
β-Cell deficiency for the ATP binding cassette transporter A1 (ABCA1), which mediates the efflux of cellular cholesterol, leads to altered ...
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#77Posttranslational Mechanisms of HDL Regulation, ABCA1
ABCA1. In addition to the transcriptional and posttranscriptional mechanisms described above, the expression of ABCA1 is also regulated at the ...
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#78Global ABCA1 Antibody Market 2021 Size, Share, Trends ...
New Report on “ ABCA1 Antibody Market size | Research Industry Segment by Applications (Immunofluorescence , Immunohistochemistry Paraffin ,
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#79Jieli ic. 29/ Piece. Co. Office Hours: 8:00 AM – 5:00 PM ...
Compared with intraventricular infusion of artificial CSF in ABCA1−B/−B stroke mice, no significant differences in the lesion volume (Figure IIA in the ...
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#80Europe Indolent Lymphoma Treatment Market Growth Trends ...
Global ABCA1 Antibody Market 2021 Growth, Latest Trend Analysis and Forecast 2027. February 22, 2022. Global Alcoholic Tea Market Size, ...
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#81Cuota de mercado de hornos de oxidación a nivel de chip ...
19 小時前 — Tamaño del mercado de Anticuerpo ABCA1 y perspectiva hasta 2028: estimaciones de capacidad de producción, valor CAGR, tendencias actuales de ...
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