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Physiologically Based Pharmacokinetic (PBPK) Modeling and ...

dA M,i = kilm,GUi × EGUi,isoform × A ABS,GUi Vent,GUi Km + A ABS,GUi V ent,GUi (4.41) dt isoform AM,i is order rate the amount of drug metabolized constant ...

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