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並前往https://www.researchgate.net/figure/Relevant-basic-interactions-between-Itk-PIP3-and-IP4-Following-TCR-pMHC-binding-Itk_fig6_257072534

Relevant basic interactions between Itk, PIP3 and IP4 ...

PIP3 bound Itk phosphorylates and thereby activates LAT-bound PLCγ1. Activated PLCγ1 then hydrolyzes the membrane lipid PIP2 into the soluble second messenger ...

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