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並前往https://www.alzforum.org/news/research-news/sans-nuclear-tdp-43-splicing-alsftd-gene-goes-awry

Sans Nuclear TDP-43, Splicing of An ALS/FTD Gene Goes Awry

Neurons lacking nuclear TDP-43 mis-splice UNC13A, make less of the protein. UNC13A risk variants incorporate cryptic exons. This only occurs in ...

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