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#1淋巴球功能性抗原1 - 维基百科，自由的百科全书
淋巴球功能性抗原1（英文：Lymphocyte function-associated antigen 1, LFA-1）是淋巴球上的細胞黏附分子，屬於黏附分子中整合素（integrin）超家族。 ... LFA-1對淋巴球的 ...
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#2Lymphocyte Function Associated Antigen 1 - an overview
LFA -1 is a β2-integrin expressed on the vast majority of thymocytes and bone marrow cells, and on all mature T cells, B cells, monocytes, and granulocytes. LFA- ...
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#3LFA-1 in T Cell Migration and Differentiation - Frontiers
LFA -1 is a key T cell integrin that plays a critical role in the regulation of these functions. With this highly diverse set of roles, it is ...
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#4LFA-1 (CD11a) as a therapeutic target - PubMed
由 MR Nicolls 著作 · 2006 · 被引用 111 次 — Leukocyte function associated antigen-1 (LFA-1) was one of the earliest of cell-surface molecules identified by monoclonal antibodies generated against ...
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#5CD18 (LFA-1 beta) Antibody, FITC (11-0189-42) - Thermo Fisher
Invitrogen Anti-CD18 (LFA-1 beta) Monoclonal (6.7), eBioscience™, Catalog # 11-0189-42. Tested in Flow Cytometry (Flow) applications.
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#6LFA-1 in T cell priming, differentiation, and effector functions
One of the major leukocyte integrins on T cells is LFA-1 (CD11a/CD18 or αLβ2), which, apart from orchestrating the APC–T cell interface in an ...
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#7APC anti-human CD11a/CD18 (LFA-1) Antibody - BioLegend
It is heterodimeric cell surface receptor expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, ...
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#8Lifitegrast, LFA-1 (lymphocyte function-associated antigen-1 ...
MW 615.48, Purity > 98%. LFA-1 (lymphocyte function-associated antigen-1) antagonist intended for the treatment of vascular complications of the eye.
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#9LFA-1–mediated Adhesion Is Regulated by Cytoskeletal ...
Using lymphocyte function-associated antigen-1 (LFA-1) on T cells as a model, we have investigated adhesion to ligand intercellular adhesion molecule-1 ...
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#10LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly ...
LFA -1 and Mac-1 are key integrins that regulate leukocyte adhesion and migration in inflamed tissues. Despite considerable advances in our ...
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#11LFA-1 Ligation by High-Density ICAM-1 Is Sufficient To ...
However, the functional impact of LFA-1 on the activation of iNKT cells and other innate T lymphocyte subsets has remained largely unexplored.
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#12LFA-1, CD11a/CD18
Leukocyte Function-Associated Antigen One (LFA-1, CD11a/CD18). Resources on LFA-1 are under construction for this web site. Some of the pages linked here ...
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#13Topical Leukocyte Function-Associated Antigen-1 (LFA-1 ...
Purpose : The leukocyte function-associated antigen-1 (LFA-1) binds to the intercellular adhesion molecule (ICAM) family, with its principal ligand being ...
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#14InVivoMAb anti-mouse LFA-1α (CD11a) - Bio X Cell
The M17/4 monoclonal antibody reacts with mouse LFA-1α (lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a.
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#15Which medications in the drug class LFA-1 Antagonists are ...
The integrin lymphocyte function-associated antigen-1 (LFA-1) interacts with ICAM-1 to contribute to the formation of an immunological synapse, resulting in ...
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#16Comparative normal mode analysis of LFA-1 integrin I-domains.
The conformational dynamics of the Inserted domain (I-domain) from the lymphocyte function-associated antigen-1 (LFA-1) was investigated by normal mode ...
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#17Identification of neutrophil β2-integrin LFA-1 as a potential ...
Lymphocyte function-associated antigen-1 (LFA-1) is an αL (CD11a) and β2 (CD18) integrin subunit, which interacts with intercellular adhesion ...
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#18How Do LFA-1 Antagonists Work? - Uses, Side Effects, Drug ...
Lymphocyte function-associated antigen-1 (LFA-1) antagonists are ophthalmic medications that prevent eye inflammation caused by dry eyes.
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#19PE/Cy7 anti-human CD11a/CD18 (LFA-1) - Sony Biotechnology
It is heterodimeric cell surface receptor expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, ...
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#20The magnitude of LFA-1/ICAM-1 forces fine-tune TCR ...
This key process in adaptive immunity is sparked upon T cell receptor (TCR) binding of antigens within cell-cell junctions stabilized by integrin (LFA-1)/ ...
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#21042053 - LFA-1[-] Strain Details - The Jackson Laboratory
Itgal (LFA-1) knock-out mice exhibit defective leukocyte adhesion, reduced NK cytoxicity, absent DTH, and a selective defect in the induction of peripheral ...
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#22Human LFA-1 alpha (Plasmid #8630) - Addgene
Plasmid Human LFA-1 alpha from Dr. Timothy Springer's lab contains the insert LFA1 alpha and is published in J Cell Biol 1989 Feb;108(2):703-12.
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#23Leukocyte adhesion glycoprotein LFA-1 alpha chain - UniProt
Leukocyte adhesion glycoprotein LFA-1 alpha chainImported. <p>Information which has been imported from another database using automatic procedures.
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#24LFA-1 Antibodies, cDNA Clones Research Reagents - 义翘神州
ITGAL (Integrin Subunit Alpha L, also known as CD11A; LFA-1; LFA1A), located on 16p11.2, is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish.
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#25Deficiency of a leukocyte surface glycoprotein (LFA-1) in two ...
Deficiency of a leukocyte surface glycoprotein (LFA-1) in two patients with Mo1 deficiency. Effects of cell activation on Mo1/LFA-1 surface expression in ...
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#26LFA-1 integrin antibodies inhibit leukocyte α 4 β 1 - ASH ...
Binding of intercellular adhesion molecule-1 to the β2-integrin leukocyte function associated antigen-1 (LFA-1) is known to induce ...
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#27Dimerization and the effectiveness of ICAM-1 in mediating ...
Abstract. Dimeric intercellular adhesion molecule-1 (ICAM-1) binds more efficiently to lymphocyte function-associated antigen-1 (LFA-1) than ...
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#28LFA-1 signals to promote actin polymerization and upstream ...
These events require the T cell integrins LFA-1 and VLA-4 and their endothelial ligands ICAM-1 and VCAM-1, respectively. T cells migrate against ...
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#29Cell Adhesion Receptors of the Immune System - Annual ...
The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion ... Figure 1: Model for T cell activation following antigen recognition.
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#30LFA-1_百度百科
LFA（Lymphocyte Function-associated Antigen）是指淋巴細胞功能相關分子。LFA-1侷限在白細胞上表達,分佈廣泛,可參與細胞毒T細胞(cytotoxic T lymphocyte,CTL), ...
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#31LFA-1 Antagonists - Prices and Information - GoodRx
LFA -1 (lymphocyte function-associate) antagonists are used to treat dry eyes. They block the interaction of certain proteins with white blood cells, ...
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#32LFA-1 antagonist (BIRT377) similarly reverses peripheral ...
LFA -1 antagonist (BIRT377) similarly reverses peripheral neuropathic pain in male and female mice with underlying sex divergent peripheral immune ...
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#33Role of LFA-1/ICAM-1 interaction in the formation of the ...
APC, antigen-presenting cell; ICAM-1, intercellular adhesion molecule-1; LFA-1, lymphocyte function-associated antigen-1; MHC, major histocompatibility complex; ...
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#34Role of ICAM-1/LFA-1 interaction in the angiogenic and ...
During metastatic progression, a stromal and tumor cell crosstalk mediated by hepatic ICAM-1 and tumor LFA-1 interaction modulate the tumor microenvironment ...
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#35Kilogram Synthesis of a LFA-1/ICAM Inhibitor - ACS Publications
Interaction between leukocyte function-associated antigen-1 (LFA-1), expressed on the surface of cytokine-stimulated cells, ...
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#36LFA-1 Definition & Meaning | Merriam-Webster Medical
The meaning of LFA-1 is an integrin that is a heterodimeric protein on the surface of white blood cells and that functions in the adhesion of lymphocytes to ...
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#37LFA-1 decreases the antigen dose for T cell activation in vivo
Abstract. Leukocyte adhesion molecule leukocyte function-associated antigen (LFA)-1 not only mediates intercellular binding but also ...
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#38Generation of an LFA-1 Antagonist by the Transfer of the ICAM ...
Generation of an LFA-1. Antagonist by the Transfer of the ICAM-1 Immunoregulatory. Epitope to a Small Molecule. T. R. Gadek,l* D. J. Burdick,l* R. S. ...
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#391XDG: X-ray structure of LFA-1 I-domain in complex with ...
The integrin lymphocyte function-associated antigen-1 (LFA-1) (alphaLbeta2; CD11a/CD18) plays an important role in leukocyte migration and T cell activation.
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#40Impact of NKT Cells and LFA-1 on Liver Regeneration under ...
Wild-type (WT) and LFA-1-/- mice underwent a 2/3 PH and low-dose lipopolysaccharid (LPS) application. Hepatocyte proliferation, immune cell ...
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#411/18 Autoart Lexus LFA 黑盒signature 1:18 精裝版 - 蝦皮
... 者請迴避照片不是拍好玩的，眼睛也不是裝飾用的品項如圖，下單表示接受品項會妥善包裝，不負責運送風險購買1/18 Autoart Lexus LFA 黑盒signature 1:18 精裝版.
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#42Expression of ICAM‐R (ICAM‐3), a novel counter‐receptor for ...
Expression of ICAM-R (ICAM-3), a novel counter-receptor for LFA-1, in rheumatoid and nonrheumatoid synovium · References · Related · Information.
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#43Organization of the Integrin LFA-1 in Nanoclusters Regulates ...
The β2-integrin LFA-1 facilitates extravasation of monocytes (MOs) into the underlying tissues, where MOs can differentiate into dendritic cells (DCs).
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#44Identification of Amino Acids in the CD11a I-domain Important ...
Leukocyte function-associated antigen-1 (LFA-1) is a cell surface adhesion receptor for intercellular adhesion molecule-1, −2, ...
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#45T Cells Expressing Activated LFA-1 Are More Susceptible to ...
ABSTRACT The incorporation of host-derived proteins in nascent human immunodeficiency virus type 1 (HIV-1) particles is a well-established ...
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#46LFA 1/18的價格推薦- 2022年3月| 比價比個夠BigGo
LFA 1 /18價格推薦共5筆商品。還有maxx m21 18、maisto 1 18、Roland fp 18。現貨推薦與歷史價格一站比價，最低價格都在BigGo！
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#47Small molecule antagonists of the LFA-1/ICAM-1 interaction ...
The interaction between leukocyte function-associated antigen-1 (LFA-1), a member of β2 integrin family, and intracellular adhesion molecule-1 (ICAM-1) ...
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#48Biologics in General Medicine - 第 42 頁 - Google 圖書結果
LFA -1 belongs to the family of 2 integrins and is expressed on the surface of ... LFA-1 is essential for every step in the process ofimmune surveillance and ...
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#49Hycult Biotech Inc CD11/CD18 (LFA-1), HMN, 20UG - Fisher ...
Shop Hycult Biotech Inc CD11/CD18 (LFA-1), HMN, 20UG at Fishersci.com.
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#50Participation of Mac-1, LFA-1 and VLA-4 integrins in the in ...
The integrins Mac-1, LFA-1 and, interestingly, VLA-4 mediate the adhesion of sickle cell disease leukocytes to activated endothelial cell layers ...
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#51ICAM-1 and LFA-1 play critical roles in LPS-induced ...
inflammation, and LFA-1 serves as a ligand of ICAM-1 in the lung. intercellular adhesion molecule; lymphocyte function-associated an-.
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#52Increased Expression of Leukocyte Function Associated ...
Leukocyte function associated antigen-1 (LFA-1) and its ligand intercellular adhesion molecule-1 (ICAM-1) are cell adhesion molecules that play an important ...
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#53LFA-1 Integrin β Chain Phosphorylation Regulates Protein ...
1. INTRODUCTION TO LEUKOCYTE INTEGRINS. 9. 2. LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1. 2.1 T cell adhesion. 10. LFA-1 in T cell migration.
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#54Proteomic analysis in primary T cells reveals IL-7 alters T cell ...
Given that CYTIP influences the intracellular localisation of cytohesin-1 [23], and cytohesin-1 impacts LFA-1 interaction and cytoskeletal rearrangements during ...
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#55Effect of aerobic exercise on blood lipid and ICAM-1,LFA-1 in ...
The levels of serum lipid profile,ICAM-1,and LFA-1 were significantly different between HF rats and control rats.Compared with HF rats,serum levels of TG,TC,LDL ...
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#56Research programme: LFA-1 inhibitors - Actinobac Biomed
Actinobac Biomed is developing a lymphocyte function-associated antigen-1 inhibitor, called Leukothera®, for the treatment of haematological malignancies,
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#57Lifitegrast (SAR 1118) | LFA-1/ICAM-1 Antagonist
Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1; αLβ2) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an ...
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#58Lfa-1 | Sigma-Aldrich
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide). Sinónimos:CD11A, LFA-1, LFA1A.
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#59Lexus LFA 1/18 Matte Black - Amazon UK
Shop Lexus LFA 1/18 Matte Black. Free delivery and returns on eligible orders of £20 or more.
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#60The leukocyte integrin LFA-1 reconstituted by cDNA ...
The functional activity of lymphocyte function-associated antigen 1 (LFA-1) on leukocytes can be regulated by T-cell receptor (TCR) stimulation and ...
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#611/16-1/2in lfa 5322a3/8-24 keyless chuck - KBC Tools ...
LFA,1/16-1/2IN LFA 5322A3/8-24 KEYLESS CHUCK,1-507-523,KBC Tools & Machinery.
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#62LFA-1/ICAM-1 Interaction Lowers the Threshold of B Cell ...
The integrin LFA-1 and its ligand ICAM-1 mediate B cell immunological synapse between the B cell and antigen-.
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#63Space Availability - LFA 1/Group 10 - Information Bookings
LFA 1 /Group 10 (University Library: Fairhurst) Capacity: 4. You have reached the end of the bookable window. No availability will be shown ...
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#64Micropatterning of TCR and LFA-1 ligands reveals ...
LFA -1 interact in the context of the immunological synapse in T cells; augmentation of TCR signalling by LFA-1 provides efficient activation ...
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#65FRET based quantification and screening technology platform ...
The interaction between leukocyte function-associated antigen-1(LFA-1) and intercellular adhesion molecule-1 (ICAM-1) plays a pivotal role ...
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#66lfa-1 immunodeficiency disease
LFA -1 IMMUNODEFICIENCY DISEASE. Definition of the Genetic Defect and Chromosomal Mapping of a and a. Subunits of the Lymphocyte Function-associated Antigen ...
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#67Differential nanoscale organisation of LFA-1 modulates T-cell ...
The heterodimeric transmembrane integrin LFA-1 (αLβ2 integrin) regulates adhesion and migration of effector T-cells through linkage of the extracellular matrix ...
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#68【LFA Firmapress 賦形劑紫色1KG】LFA ... - MoMo購物
推薦【LFA Firmapress 賦形劑紫色1KG】LFA Firmapress 賦形劑紫色1KG(賦形劑成形脫 ... 1 / 2. Firmapress 賦形劑 ... LFA特别設計了這款添加劑，讓製錠過程簡單輕鬆。
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#6965 下列何者會與LFA-1（lymphocyte functional an.. - 阿摩線上 ...
65 下列何者會與LFA-1（lymphocyte functional antigen-1）分子作用而影響血球細胞的移動？ (A) VCAM-1（vascular cell adhesion molecule-1） (B) fibronectin
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#70LFA-1_搜狗百科
LFA（Lymphocyte Function-associated Antigen）是指淋巴细胞功能相关分子。LFA-1局限在白细胞上表达,分布广泛,可参与细胞毒T细胞(cytotoxic T lymphocyte,CTL), ...
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#71CD11a/CD 18 (LFA-1) Epitopes Involved in Syncytium ...
由 J GOUDSMIT 著作 · 1990 · 被引用 12 次 — associated antigen-1 (LFA-1) block syncytium formation when added to CD4+ T-cells before or shortly after (5 min) cell free HIV-1 is added.
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#72TIGIT in cancer immunotherapy
CD226 associates with LFA-1 and binds CD155 to deliver a positive signal. ... In cancer, TIGIT is coexpressed with PD-1 on tumor antigen-specific CD8 + T ...
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#73Moléculas de adhesión: Importancia en la respuesta inmune e ...
LFA -1. Células endoteliales no activadas y leucocitos en reposo. ICAM-3. CD50. LFA-1, a D b 2. Células derivadas de la médula ósea ...
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#741/24 scale model カーモデル車模製作過程及作品展示【GC ...
TAMIYA 1 /24 LEXUS LFA - Car model - 1 /24 scale model カーモデル車模製作過程及作品展示【GC模型世界】. 2,282 views2.2K views. Dec 13, 2019.
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#75Epidermal Langerhans Cells - 第 183 頁 - Google 圖書結果
... common B- subunit : the lymphocyte functionassociated antigen ( LFA - 1 ) , the C3bi complement receptor ( OKM1 / Mac - 1 ) , and the p 150,95 molecule ...
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#761–deficient Mice to Determine the Role of LFA-1, Mac-1, and 4 ...
the 2 integrins, lymphocyte function–associated antigen (LFA)-1, and Mac-1. ... Key words: LFA-1 • integrin • rolling • neutrophils • inflammation.
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#77T Cell Migration from Inflamed Skin to Draining Lymph Nodes ...
1-24-2017. T Cell Migration from Inflamed Skin to Draining Lymph Nodes. Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1.
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#78SARS-CoV-2 Actively Infects And Kills Lymphoid Cells - Forbes
One of the critical symptoms of SARS-CoV-2 infection is lymphopenia. ... When LFA-1 was overexpressed, it also promoted SARS-CoV-2 infection ...
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#80Adhesion Molecules: Function and Inhibition
antigen-1. (LFA-1). and. macrophage. antigen-1. (Mac-1):. Cooperative. partners. in. leukocyte. emigration. and. function. Alan R. Schenkel1 and Minsoo Kim2 ...
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#81Used Lexus LFA for Sale in Chicago, IL (Test Drive at Home)
Shop, watch video walkarounds and compare prices on Used Lexus LFA listings in ... Your Search1 Results. Lexus. Used. LFA. Clear Filters. Search Location.
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#82Lexus lfa 1:18 autoart sold out - Diecast Model - Sahibinden.com
Lexus lfa 1:18 autoart sold out - Diecast Model Araba uygun fiyatlarla alışverişte ilk adres sahibinden.com'da.
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#83RAF operational low flying training timetable - GOV.UK
From: Ministry of Defence; Published: 1 August 2011 ... LFA 7(T): central Wales; LFA 14(T): northern Scotland; LFA 20(T): the borders of southern Scotland ...
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#84WhatsApp Web
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#85Platelets - 第 297 頁 - Google 圖書結果
Mac-1 (αMβ2, CD11b/CD18) and LFA-1 (αLβ2, CD11a/CD18) mainly mediate firm adhesion of neutrophils, monocytes, and some subclasses of lymphocytes to ...
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#86The Adhesive Interaction of Cells - 第 131 頁 - Google 圖書結果
LFA -1 binding site in ICAM-3 contains a conserved motif and non-contiguous ... the binding site for CD58 lies on one face of the first domain of human CD2.
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#87Pathologic Basis of Veterinary Disease - 第 114 頁 - Google 圖書結果
Adhesion molecules are divided into (1) selectins (E-, L-, and P-selectin), (2) integrins (VLA family of β1 integrins; β2 integrins [Mac-1, LFA-1, p150,95, ...
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#88M Fritzsche et al (@FritzscheLab) / Twitter
1. 3. M Fritzsche et al Retweeted ... Magnesium sensing via LFA-1 regulates CD8+ T cell effector function - ScienceDirect. sciencedirect.com.
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#89Advances in Immunology - 第 54 頁 - Google 圖書結果
... molecules (e.g., LFA-1) in cell contact or B cell activation. One explanation for these results is that weak interactions between B cells and activated ...
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#90LFA - Official Site of Legacy Fighting Alliance
FRIDAY, APRIL 8 LFA 128: McKENZIE vs. CLAY MAIN EVENT: AARON McKENZIE vs. LUCAS CLAY LIGHTWEIGHT WORLD TITLE FIGHT LIVE on UFC FIGHT PASS® SANFORD PENTAGON ...
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#91Lincoln Financial: Individuals
When you work with one of our affiliated financial professionals, you can rest assured that your best interests are always the top priority.
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#92Experimental Approaches to Diabetic Retinopathy
63 Katagiri K, Maeda A, Shimonaka M, Kinashi T: RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1.
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#93Lexus | Experience Amazing
Welcome to Lexus; official site. Explore the line of Lexus luxury sedans, SUVs, hybrids, performance cars and accessories, or find a Lexus dealer near you.
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#94LFA 熱傳導分析儀(閃光法)全拓科技有限公司 Trendtop 實驗室 ...
Thermal Diffusivity and Conductivity LFA Laser Flash Apparatus 品牌:NETZSCH 產地:德國型號:LFA 467 HT/LFA 467/LFA 457 /LFA 427. 商品簡介：. 1. 量測範圍廣.
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#95MMA Schedule 2022 | ESPN
Date EVENT FIGHT OF THE NIGHT Apr 16 Rizin FF: Rizin Fighting Federation 35 Apr 16 UFC Fight Night: Luque vs. Muhammad 2 Bueno Silva vs. Yanan Apr 15 Rizin FF: Trigger 3rd
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#96Alfa Laval - heat transfer, separation, fluid handling
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#97Linseis LFA 500 - measuring the thermal conductivity
Worlds only combined solution for combined heat loss and finite pulse corrections for the flash method. One fits all model. No more uncertainty of selecting the ...