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#1Resolvase - an overview | ScienceDirect Topics
The term resolvase is used to describe a related family of site-specific recombinases that function to excise (as a circle) a segment of DNA contained ...
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#2Resolvase - Proteopedia, life in 3D
Resolvase or recombinase (Rec) is a nuclease which is involved in DNA recombination. According to the binding residue, the recombinases are grouped to Tyr- ...
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#3Serine Resolvases - PMC - NCBI
The resolvase catalytic domain contains a small α/β fold containing the catalytic serine followed by a long helix (helix E) that is sometimes now considered ...
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#4Resolvase Definition and Examples - Biology Online Dictionary
Resolvase is an enzyme known for its repressive function against transposases. See also: transposition · transposon; transposase; recombinase.
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#5Mutants of Tn3 resolvase which do not require accessory ...
Tn3 resolvase promotes site-specific recombination between two res sites, each of which has three resolvase dimer-binding sites. Catalysis of DNA-strand ...
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#6In vitro site-specific integration of bacteriophage DNA ... - PNAS
The resolvase/invertase family of enzymes (e.g., Tn3 or γδ resolvases, Mu Gin invertase) act via a concerted, four-strand staggered break and rejoining ...
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#7Site-Specific Recombination by Tn3 Resolvase - Cell Press
Resolvase is not structurally related to integrase (Argos et al., 1986), it differs in the polarity of strand cleavage (Reed and Grindley, 1981) and it has not.
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#8Structural basis for topological regulation of Tn3 resolvase
Tn3 resolvase has long been known to be regulated by DNA topology—that is, it will cut and reconnect two target sequences only if they lie on the same DNA ...
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#9Structural insights into sequence-dependent Holliday junction ...
Holliday junctions (HJs) are key DNA intermediates in genetic recombination and are eliminated by nuclease, termed resolvase, ...
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#10Resolvase/invertase-type recombinase catalytic domain profile
called the serine recombinases or resolvase/invertase family, groups enzymes which share the following structural characteristics: an N-terminal catalytic ...
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#11parA - Resolvase - Escherichia coli | UniProtKB | UniProt
Resolvase. Gene. parA. Status. UniProtKB reviewed (Swiss-Prot). Organism. Escherichia coli. Amino acids. 219. Protein existence. Inferred from homology.
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#12Resolvase definition and meaning | Collins English Dictionary
Between 6 and 24 genes per plasmid were annotated as transposase, resolvase, integrase, recombinase or invertase. Carsten Kuenne, Sonja Voget, Jordan ...
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#13Resolvase domain annotation - SMART
The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to ...
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#14Human Holliday junction resolvase GEN1 uses a ... - eLife
Classical HJ resolvases introduce two symmetrical incisions across the junction point by coordinating the action of two active sites. The first ...
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#15Structural basis for topological regulation of Tn3 resolvase
Introduction. Tn3 resolvase belongs to a family of “small serine recombinases”. The serine recombinases are characterized by an active site ...
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#16Resolvase-In Vivo Expression Technology Analysis of the ...
Resolvase -In Vivo Expression Technology Analysis of the Salmonella enterica Serovar Typhimurium PhoP and PmrA Regulons in BALB/c Mice.
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#17Transposition: Forty-third Symposium of the Society for ...
First , this region of resolvase may be involved in dimer formation . This seems unlikely because in a preliminary study some of these mutants exhibit ...
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#18resolvase - Wiktionary
EnglishEdit. EtymologyEdit · resolve + -ase? NounEdit. resolvase (plural resolvases). (biochemistry) Any of a group of enzymes that repress transposases ...
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#19Telomere resolvase - Wikipedia
Telomere resolvase, also known as protelomerase, is an enzyme found in bacteria which contain linear plasmids. FunctionEdit. In order to prevent exonuclease ...
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#201ZR2: Structure of a Synaptic gamma-delta Resolvase ...
This resolvase, activated for recombination by mutations, forms a tetramer whose structure is substantially changed from that of a presynaptic complex between ...
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#21Analysis of a Nucleoprotein Complex: the Synaptosome of γδ ...
The γδ resolvase protein is one of a large family of transposon-encoded site-specific recombinases. It performs recombination in a DNA-protein complex that ...
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#22Molecular characterization of the resolvase gene, res, carried ...
Molecular characterization of the resolvase gene, res, carried by a multicopy plasmid from Clostridium perfringens: common evolutionary origin for prokaryotic ...
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#23Resolvase-Mediated Site-Specific Recombination | SpringerLink
Abdel-Meguid SS, Grindley NDF, Templeton NS, Steitz TA (1984) Cleavage of the site-specific recombination protein γδ resolvase; the smaller fragment binds DNA ...
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#24Analysis of γ δ Resolvase Mutants in vitro - JSTOR
interaction between serine-10 of resolvase and site I of res. (site-specific recombination/transposon y8/proteln-DNA complexes).
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#25DNA Topology - 第 176 頁 - Google 圖書結果
Substrate O Singly - linked catenane ( 2 ) First recombination Observed resolvase products Four - noded knot ( 2,2 ) Figure - eight catenane ( 3 + ...
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#26Molecular Biology of Nucleases - 第 109 頁 - Google 圖書結果
Resolvase A number of transposons such as yo ( a 5700 bp element related to Tn - 3 transposon ; Heffron et al . , 1979 ) , Tn - 3 ( Reed , 1981 ) , Tn - 21 ...
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#27Structural Insights Into Gene Expression And Protein Synthesis
Crystal Structure of the Site - Specific Recombinase yd Resolvase Complexed with a 34 bp Cleavage Site RESEARCH ARTICLES movement, so that the nearby ...
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#28Phosphorylation of the Archaeal Holliday Junction Resolvase ...
Our results revealed that HJ resolvase is regulated by protein phosphorylation, reminiscent of the regulation of eukaryotic HJ resolvases ...
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#29Crucial Genetic Diversity Enzyme Long Sought by Biologists ...
McGowan, both of The Scripps Research Institute (TSRI), identify the "resolvase" enzyme that may be responsible for generating genetic diversity during sexual ...
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#30THE TOPOLOGY OF TN3 RESOLVASE | Calculating the ...
Read chapter THE TOPOLOGY OF TN3 RESOLVASE: As researchers have pursued biology's secrets to the molecular level, mathematical and computer sciences have .
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#31Plasmid Collections - DNASU |
Description: Resolvase, N terminal domain. Total number of clones in the collection: 78. Price: $ 546.0 ($7.00 per clone). Use Restriction: No restriction ...
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#32A Novel Role of Human Holliday Junction Resolvase GEN1 in ...
We find homologous recombination severely impaired in GEN1 deficient cells, suggesting that GEN1 functions as a Holliday junction resolvase in vivo as well as ...
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#33Structural basis for topological regulation of Tn3 resolvase
Tn3 resolvase will cut and reconnect two target sequences only if they lie on the same DNA molecule, and if they are in the proper relative ...
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#34The Sekelsky Lab Research - Resolvases
pombe Mus81-Eme1 was the first candidate nuclear resolvase (Boddy 2001). This enzyme actually cuts nicked Holliday junctions and replication fork structures ...
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#35Resolvase | Request PDF - ResearchGate
Request PDF | Resolvase | Resolvases are recombinases involved in site-specific recombination. The best studied are those from Tn. 3-family transposons that ...
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#36Catalytic Residues of the Telomere Resolvase ResT
Catalytic Residues of the Telomere Resolvase ResT. A PATTERN SIMILAR TO, BUT DISTINCT FROM, TYROSINE RECOMBINASES AND TYPE IB. TOPOISOMERASES*□S.
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#37Crystal Structure of the Site-Specific Recombinase γδ ...
The structure of γδ resolvase complexed with a 34 bp substrate DNA has been ... from the resolvase catalytic domains at the recombination crossover point.
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#38Searching for the human resolvase
However, no eukaryotic nuclear resolvase is known. A human activity has been identified that fits the RuvABC resolvasome paradigm - it cuts Holliday junctions ...
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#39The search for a human Holliday junction resolvase
In 2008, after a search that lasted almost 20 years, a Holliday junction resolvase was identified in humans. The protein, GEN1, was identified ...
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#40RuvC resolvase vs Holliday Junction Resolvase - SEA-PHAGES
The official list has RuvC resolvase, but all my HHPRED hits for some of our genes are hitting Holliday Junction Resolvase (which I am ...
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#41Recombinant Escherichia coli Transposon gamma-delta ...
Purchase Recombinant Escherichia coli Transposon gamma-delta resolvase(tnpR). It is produced in Yeast. High purity. Good price.
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#42Cdc14 targets the Holliday junction resolvase Yen1 to the ...
The only canonical Holliday junction (HJ) resolvase identified in eukaryotes thus far is Yen1/GEN1. Nevertheless, Yen1/GEN1 appears to have a minor role in ...
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#43EP0760002B1 - Detection of mutation by resolvase cleavage
In yet other preferred embodiments, the test DNA is equal to or greater than 100 nucleotides in length; and either the resolvase reaction of step (c) is carried ...
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#44Resolvase-like recombination performed by the TP901-1 ...
Keywords: lactococcal bacteriophage, extended resolvase, site-specific recombination, mechanism of recombination, chromosomal attachment site. INTRODUCTION.
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#45Erratum to: The Holliday junction resolvase RecU is required ...
The Holliday junction resolvase RecU is required for chromosome segregation and DNA damage repair in Staphylococcus aureus. BMC Microbiol. 2013; ...
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#46Synapsis and catalysis by activated Tn3 resolvase mutants
The serine recombinase Tn3 resolvase catalyses recombination between two 114 bp res sites, each of which contains binding sites for three resolvase dimers.
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#47rsvA - Resolvase - WikiGenes
We studied the dynamics of site-specific recombination by the resolvase encoded by the Escherichia coli transposon Tn3 [1]. We obtained identical results for ...
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#48Mobile DNA III - 第 250 頁 - Google 圖書結果
Site-specific recombination by Tn3 resolvase. Trends Genet 5: 304–309. 18. Watson MA, Boocock MR, Stark WM. 1996. Rate and selectively of synapsis of res ...
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#49resolvase在線翻譯- 英語 - 海词
海詞詞典,最權威的學習詞典,為您提供resolvase的在線翻譯,resolvase是什麼意思,resolvase的真人發音,權威用法和精選例句等。
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#50Mutants of Tn3 resolvase - CORE
due to the deletion of a plasmid-encoded galK gene by resolvase-catalysed recombination. Two specific mutants of TnJ resolvase were made, Y6F and E124Q.
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#51Resolvase-catalysed reactions between res sites differing in ...
The resolvase-catalysed reaction between two res sites in a circular DNA substrate normally gives two circular recombination products linked in a two-noded ...
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#52detection of mutation by resolvase cleavage - Patentscope
In preferred embodiments of the invention, the resolvase is bacteriophage T4 endonuclease VII.
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#53A new role for Holliday junction resolvase Yen1 in processing ...
A new role for Holliday junction resolvase Yen1 in processing DNA replication intermediates exposes Dna2 as an accessory replicative ...
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#54Structure And Metal Binding Properties Of A Poxvirus Resolvase
Poxviruses encode a resolvase enzyme that cleaves 4-way junctions extruded at the concatemer junctions, a process that is essential for viral replication.
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#55Holliday junction resolvase GEN1 functions as a versatile ...
Human Holliday junction resolvase GEN1 seems to be an enzyme of last resort for recognizing and cleaving a specific range of DNA structures.
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#56Tn3 resolvase-like sequence in P transposable element of ...
Tn3 resolvase-like sequence in P transposable element of Drosophila melanogaster. BY Yoko SATTA*, Takashi GOJOBORI**, Takeo MARUYAMA** and Sadao I. CHIGUSA*.
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#57Catalytic Domain of γδ Resolvase | NMR Structural Biology ...
... organism. γδ resolvase is a site-specific DNA recombinase that catalyzes the final stage of the γδ DNA transposition in E. coli to form two catenated .
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#58Mapping interactions between the catalytic domain of ...
Mapping interactions between the catalytic domain of resolvase and its DNA substrate using cysteine-coupled EDTA-iron.
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#59Nucleic Acids and Molecular Biology
Newman BJ, Grindley NDF (1984) Mutants of the yö resolvase, a genetic analysis of the recombination function. Cell 38:463-469 Parker CN, Halford SE (1991) ...
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#60Catalysis of site-specific recombination by Tn3 resolvase.
This work describes how studies on activated mutants of two serine recombinases, Tn3 resolvase and Sin, are providing insights into the ...
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#61Structural and Functional Characterization of the Holliday ...
DrRuvC Is a Typical Holliday Junction Resolvase. Bioinformatics analysis showed that DR_0440 from D. radiodurans is a RuvC homolog (we designate ...
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#62Protein-Nucleic Acid Interactions: Structural Biology
The resolvase enzymes from gd and Tn3 transposons have been extensively studied and a great deal of our current knowledge about the SR family comes from ...
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#63Resolvase - YouTube
Resolvase. Watch later. Share. Copy link. Info. Shopping. Tap to unmute. If playback doesn't begin shortly, try restarting your device.
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#64Recombination by resolvase is inhibited by lac repressor ... - Wikidata
Recombination by resolvase is inhibited by lac repressor simultaneously binding operators between res sites. scientific article published in August 1987.
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#65The Structure of Bacteriophage T7 Endonuclease I: A Holliday ...
The penultimate step in DNA recombination is regulated by a junction resolving enzyme or 'resolvase'. This enzyme cleaves the Holliday junction resulting in ...
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#66Lorraine S. Symington Laboratory - Resolvases
Our recently published data show Mus81-Mms4 is the primary resolvase for DSB-induced mitotic crossovers in budding yeast with Yen1 serving a back-up ...
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