雖然這篇NF-κB鄉民發文沒有被收入到精華區：在NF-κB這個話題中，我們另外找到其它相關的精選爆讚文章
[爆卦]NF-κB是什麼？優點缺點精華區懶人包
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#1NF-κB - 維基百科，自由的百科全書
當處於被抑制狀態時，NF-κB位於細胞質中且與抑制蛋白IκBα形成複合體。通過內在膜受體的介導，一些胞外信號物質可激活一種稱為IκB激酶（IKK）的酶。IKK轉而 ...
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#2NF-κB signaling in inflammation - Nature
Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors, which regulates a large array of genes involved in different ...
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#3What Is Nuclear Factor Kappa B (NF-κB) Doing - Frontiers
Nuclear factor kappa B (NF-κB) is an ancient protein transcription factor (Salminen et al., 2008) and considered a regulator of innate immunity ...
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#4Molecular basis of NF-κB signaling - PubMed
NF -κB (nuclear factor kappa B) family transcription factors are master regulators of immune and inflammatory processes in response to both injury and ...
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#5What is NF-κB pathway? | MBInfo
NF -κB (nuclear factor kappa light chain enhancer of activated B cells) is a family of highly conserved transcription factors that regulate many important ...
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#6Phosphorylation of NF-κB and IκB proteins - ScienceDirect.com
Activation of NF-κB mainly occurs via IκB kinase (IKK)-mediated phosphorylation of inhibitory molecules, including IκBα. Optimal induction of NF-κB target genes ...
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#7NF-kB Transcription Factors | Boston University
Rel or NF-kappaB (NF-kB) proteins comprise a family of structurally-related eukaryotic transcription factors that are involved in the control of a large ...
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#8NFKB1 - Nuclear factor NF-kappa-B p105 subunit - UniProt
NF -kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are ...
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#9NF-κB_百度百科
核因子κB（nuclear factor kappa-B，NF-κB）蛋白最早由David Baltimore發現，該蛋白家族可以選擇性的結合在B細胞κ-輕鏈增強子上調控許多基因的表達。
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#10NF-κB Signaling
In the classical (or canonical) pathway, NF-κB/Rel proteins are bound and inhibited by IκB proteins. Proinflammatory cytokines, LPS, growth factors, and antigen ...
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#11The complexity of NF-κB signaling in inflammation and cancer
The NF-κB family of transcription factors has an essential role in inflammation and innate immunity. Furthermore, NF-κB is increasingly ...
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#12Temperature regulates NF-κB dynamics and function through ...
The nuclear factor kappa B (NF-κB) signaling pathway is a key mediator of the immune system, which regulates cell fate as well as stress and ...
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#13NF - ah-gene.com.tw
NF -κB是發炎的總開關. NF-κB (B細胞中kappa輕鏈之啟動者)是一蛋白複合體，其能控制DNA之轉錄工作。NF-κB在所有的動物細胞都可以找到它的存在，它的工作是應付諸如 ...
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#14MCPIP1抑制NF-κB活性之分子機制探討 - 臺北醫學大學
MCPIP1也被許多前發炎調節分子，像單核球趨化蛋白-1、介白素-1β、腫瘤壞死因子α以及脂多醣體，快速的誘發出來。目前已知MCPIP1具有抑制NF-κB報告基因活性的能力，在發炎 ...
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#15Understanding Immunobiology Through The Specificity of NF-κB
An early study showed that transfection of double-stranded oligonucleotides with κB sites inhibits the NF-κB-induced production of inflammatory cytokines in ...
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#16Roles of NF-κB in Cancer and Their Therapeutic Approaches
Notably, in contrast to the signal-induced processing of p100, which is tightly regulated by the non-canonical NF-κB pathway via IKKα-mediated p100 ...
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#17Mechanisms of NF-κB p65 and strategies for therapeutic ...
Two distinct NF-κB signaling pathways have been described: 1) the canonical pathway primarily activated by pathogens and inflammatory mediators, ...
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#18NF-κB and IκB | Cytokine and NF-κB Signaling - Tocris ...
NF -κB (nuclear factor-kappa B) is a rapidly acting primary transcription factor found in all cell types. It is involved in the cellular responses to stimuli ...
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#19NF-κB Signaling - Cell Press
由 V Dixit 著作 · 2002 · 被引用 270 次 — The NF-κB family of transcription factors are involved mainly in stress-induced, immune, and inflammatory responses. In addition, these molecules play important ...
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#20NF-kB inhibitors and activators | Abcam
Investigations into immunosuppressant drugs revealed cyclosporin A (CsA) to inhibit NF-κB /RelA activation and block IL-2 and IL-8 gene expression 47,48. FK506 ( ...
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#21NF-κB: a key role in inflammatory diseases - JCI
Activation of the NF-κB/Rel transcription family, by nuclear translocation of cytoplasmic complexes, plays a central role in inflammation through its ...
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#22Molecular Basis of NF-κB Signaling - Annual Reviews
NF -κB (nuclear factor kappa B) family transcription factors are master regulators of immune and inflammatory processes in response to both injury and ...
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#23The NF-κB pathway | Journal of Cell Science
The nuclear factor (NF)-κB transcription factor regulates expression of numerous components of the immune system (Li and Verma, 2002).
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#24NF-κB (p50/p65) Pathway - BioLegend
NF -κB (p50/p65) Pathway. Nuclear factor kappa B (NF-κB) is a transcription factor that is associated with inflammation. Without stimulus, NF-κB is repressed ...
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#25Multiple Facets of NF-κB in the Heart - AHA Journals
NF -κB was originally identified as a nuclear factor that bound the immunoglobulin κB light chain promoter in B lymphocytes by David ...
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#26NF-κB Signaling Pathway - Bio-Rad Antibodies
Description Specificity Target Format Host Isotype Clone Mouse anti 14‑3‑3 Theta 14‑3‑3 Theta Human Purified Mouse IgG2b AB03/2D8 Rabbit anti 14‑3‑3 Theta 14‑3‑3 Theta Human Purified Rabbit Polyclonal IgG Rabbit anti 14‑3‑3 Theta 14‑3‑3 Theta Human Purified Rabbit Polyclonal IgG
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#27The NF-kB Signaling Pathway - Creative Diagnostics
What is NF-kB? NF-kB is a short name of Nuclear Factor kappa-light-chain-enhancer of activated B cells. It is not a single protein ...
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#28NF-κB Family of Transcription Factors: Central Regulators of ...
Although many pathogens can stimulate activation of NF-κB, there are other immune molecules associated with innate immunity which activate NF-κB ...
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#29NF-κB controls the global pro-inflammatory response in ...
Here we report the complete gene expression profile from activated microvascular endothelial cells emphasizing the direct contribution of the NF-κB pathway.
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#30NF-κB与细胞凋亡
The roles of nuclear factor-kappa B (NF-κB) fa-mily and its signaling transduction pathway in apoptosis has been the focus of intense investigation all over the ...
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#31Activation of Transcription Factor NF-κB Is Suppressed by ...
Our results indicate that curcumin inhibits NF-κB activation pathway at a step before IκBα phosphorylation but after the convergence of various ...
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#32In Vivo Imaging of NF-κB Activity | The Journal of Immunology
Our transgenic mice express luciferase driven by three NF-κB response elements (i.e., sites identical with the κB site from the Igκ light chain ...
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#33NF-κB in Cancer: A Matter of Life and Death
However, NF-κB–mediated activation in the immune system has the potential to suppress tumor growth, in part through the production of growth ...
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#34NF-κB: Much Learned, Much to Learn - Science
NF -κB was originally a term coined to refer to a putative, nuclear trans-acting factor that bound the κ light-chain enhancer in B cells, and an introductory ...
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#35Importance of the alternative NF-κB activation pathway in ...
The classical activation pathway of NF-κB signaling has been identified as regulating several sporadic and inflammation-associated gastrointestinal tract ...
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#36NF-κB - DocCheck Flexikon
NF -κB ist ein spezifischer Transkriptionsfaktor, der vor allem bei der Regulation der Immunantwort, der Zellproliferation und der Apoptose einer Zelle von ...
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#37Definición de NF-kB - Diccionario de cáncer del NCI
NF -kB ... Grupo de proteínas que ayudan a controlar muchas funciones en la célula, como el crecimiento y la supervivencia. Estas proteínas también controlan las ...
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#38NF - kB in Health and Disease - 博客來
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB).
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#39NF-κB在發炎反應、細胞凋亡與癌症生成過程中的調控 - gogau
NF -κB. 與DNA 結合的複合體結構如（圖2）4所示，例圖. 中其中p50、p65 可與去氧核醣核酸上基因之啟動. 子（promoter）區域結合而活化該基因。 NF-κB 與細胞凋亡. NF-κB 對 ...
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#40NF-κB oscillations translate into functionally related patterns of ...
NF -κB oscillations synchronize to external perturbations as a damped oscillator, producing different transcription dynamics.
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#41NF-κB信号通路-免疫学专题- ABclonal
NF -κB是一个高度保守的多功能转录因子家族，包含五个成员，分别为p65（RelA）、RelB、c-Rel、NF-κB1和NF-κB2，它们会组成不同的同源或异源二聚体而发挥基因转录调节 ...
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#42Evidence of NF-ΚB Pathway Activation in Patients with ...
... the pro-inflammatory cytokines in cluster 2 linked to HMR mutations (HMR+) represented a transcriptional cluster regulated by the NF-κB ...
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#43Let-7a Targeting TNFAPI3 Promotes Vascular Endothelial Cell ...
Cells were transfected with let-7a inhibitor and/or TNFAIP3 siRNA, accompanied by pretreatment with NF-κB inhibitor PDTC or not. After being cultured in HSP ...
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#44NF-κB：バイオキーワード集｜実験医学online
NF -κB （nuclear factor κB）．NF-κBはRelA （p65），RelB，c-Rel，NF-κB1 （p105/p50），NF-κB2 （p100/p52） からなる転写因子群の総称であり，Relホモロジー ...
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#45Drug Repurposing to Treat Inflammatory Disorders? - MDPI
NF -κB is a central mediator of inflammation, response to DNA damage and oxidative stress. As a result of its central role in so many important cellular ...
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#46Yeast β-glucan increases etoposide sensitivity in lung cancer ...
EphA2 signaling includes nuclear factor kappa B (NF-κB), STAT3, and p38 mitogen-activated protein kinase (MAPK). However, treatment of cells ...
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#47Zinc Deficiency Induces Inflammation and Apoptosis via ...
The nuclear factor kappa B (NF-κB) signalling pathway is one of the major inflammatory pathways, and it regulates responses, such as apoptosis, ...
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#48Aqueous Extract of Cimicifuga dahurica Reprogramming ...
Aqueous Extract of Cimicifuga dahurica Reprogramming Macrophage Polarization by Activating TLR4-NF-κB Signaling Pathway.
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#49African swine fever virus I267L acts as an important virulence ...
Consistent with these observations, I267L inhibited activation of the IFN-β promoter, ISRE, and NF-κB induced by SeV, whose RNA is mostly sensed ...
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#50Saponin fraction isolated from Conyza blinii H.Lév ... - PubAg
Mechanistic study demonstrates that CBS is an effective NF-κB inhibitor. It inhibits p65 nuclear translocation and NF-κB downstream gene expression, including ...
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#51我国学者在心脏缺血/再灌注损伤防治方面取得进展 - 国家自然 ...
机制上， CaMKII-δ9可使NF-κB通路的IKK及IκBα发生磷酸化并降解，从而引起NF-κB通路活化和心肌细胞炎性反应（图）。抑制CaMKII-δ9明显减轻了心脏缺血/ ...
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#533種消炎藥的天然替代品(第1種常被用到） - 營養新知
... 能透過調控基因種的兩種發炎開關（ NFκB 與PPAR-γ ）來達到以下抗發炎效果 ... 多種發炎指標（如TNF-α、CRP 、NF-κB），並改善症狀，增加生活品質.
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#54암 치료 표적으로 nf-κb와 ikk - 세포 사멸 및 분화 | 조항 2022
전사 인자 NF-κB와 연관된 조절 인자 ( IκB 키나아제 서브 유닛 및 IκB 가족 구성원 Bcl-3 포함)는 다양한 혈액 종양 및 고형 종양 악성 종양에 강하게 연루되어있다.
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#55Melatonin as a safe and potentially life-saving treatment for ...
... NF-ҝB = nuclear factor kappa B; Nrf2 = transcription factor NF-E2 p45 ... the inflammatory signaling molecule nuclear factor κB (NF-κB).
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#56研究发现缓解类风湿关节炎新疗法 - 新闻
TNF通过激活NF-κB促进细胞中谷胱甘肽（GSH）生物合成，保护成纤维细胞逃逸脂质过氧化压力，抵抗铁死亡。TNF拮抗剂依那西普可显著增强低剂量铁死亡诱导 ...
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#5710 Proven Health Benefits of Turmeric and Curcumin
... a novel sulfur compound isolated from garlic via inhibition of NF-κB. ... production through inhibition of NF-kappa B activation in RAW 264.7 cells.
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#58Science @ DKFZ - German Cancer Research Center
SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB. 8. Maria Martišíková Detecting perturbations of a radiation ...
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#59Margarete Dulce Bagatini | IntechOpen
... involving known targets (i.e., p53, Ras, and NF-κB) and regulate physiopathological events such as the cellular cycle, apoptosis, and inflammation.
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#60我国学者在心脏缺血/再灌注损伤防治方面取得进展 - 生物通
机制上， CaMKII-δ9可使NF-κB通路的IKK及IκBα发生磷酸化并降解，从而引起NF-κB通路活化和心肌细胞炎性反应（图）。抑制CaMKII-δ9明显减轻了心脏缺血/ ...
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#61西安交大科研团队开发出新型抗污可注射水凝胶预防腹腔术后 ...
此外分子机制研究揭示H-HPMA水凝胶能显著降低p65蛋白、Smad3蛋白表达水平，提高Smad7蛋白的水平，有效抑制NF-κB和TGF-β1/Smad信号通路，调节了MMT相关 ...
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#62部分机构医学科研诚信案件调查处理结果（2022年2月22日）
... JNK/C-Jun and NF-κB Signaling Pathways”，经查，系存在篡改数据、编造研究过程的学术不端行为。 1.济宁第一人民医院对相关责任人作出处理如下：
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#63Effects of dietary restriction on neuroinflammation in ...
In the latter study, DR was associated with reduced transcripts of several inflammatory mediators in skeletal muscle, including NF-κB, ...
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#64The effect of two-month concurrent training and caloric ...
اســت موجبــات کاهــش فعالیــت NF-KB و روندهــای ... of NF-κB-dependent transcription is regulated by ... NF-κB signaling in skeletal muscle.
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#65Excess iodide-induced reactive oxygen species elicit iodide ...
... Phagocytosis and Inflammatory Responses to Lipopolysaccharide via Reactive Oxygen Species Generation and NF-κB Activation in Macrophages.
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#66أدوية تعالج الشيخوخة دون أن نشعر بها.. تعرفي عليها - صدى البلد
... الحرة، قد يكون لديه أيضًا خصائص أوسع مضادة للالتهابات ، لأنها تقلل من نشاط العامل النووي كابا ب ( NF - κB ) ، وهو جزيء مؤيد للالتهابات.
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#67陆军军医大学学报（原第三军医大学学报）
网站导航 · 2022年第3期预出版 · 2022年第2期预出版 · 黄芩苷通过NF-κB信号对气道上皮黏液调节因子MUC5AC和CFTR表达的影响 · SMILE与FS-LASIK矫正高度近视术后5年屈光结果及眼 ...