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[爆卦]Bufalin是什麼？優點缺點精華區懶人包
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#1Bufalin - Wikipedia
Bufalin, is a cardiotonic steroid originally isolated from the Chinese toad venom. It is a component found in many Chinese traditional medicine.
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#2Bufalin | C24H34O4 - PubChem
Bufalin is a 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the ...
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#3Bufalin - an overview | ScienceDirect Topics
It also known as Venenum bufonis, is an extract traditionally used in Chinese medicine and applied topically for anesthetic effect and as an antiarrhythmic drug ...
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#4A research update on the anticancer effects of bufalin and its ...
Bufalin (BF) is a cardiotonic steroid isolated from the Chinese toad venom, Chansu, a galenical preparation of the dried white venom of ...
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#5New therapeutic aspects of steroidal cardiac glycosides
Bufalin is a broad inhibitor of various inflammatory signaling pathways in cancer. It was noticed that in human hepatoma cells, the expression ...
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#6Bufalin | ≥99%(HPLC) | Selleck | ATPase inhibitor
Bufalin (BF) is a potent inhibitor of steroid receptor coactivator SRC-3, SRC-1 and Na+/K+-ATPase. Bufalin binds to the subunit α1, ...
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#7Determination of Endogenous Bufalin in Serum of Patients With
Bufalin is a cardiotonic steroid and a key active ingredient of the Chinese medicine ChanSu. It has significant anti-tumor activity against ...
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#8Bufalin (NSC 89595, CAS Number: 465-21-4) - Cayman ...
Bufalin is a cardiotonic steroid first isolated from toad venom and used in traditional Asian medicine. ... It inhibits the Na + /K + -ATPase transporter (Kds = 42, ...
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#9Bufalin, a Traditional Chinese Medicine Compound, Prevents ...
Chemoprevention is cost-effective for colorectal cancer when targeted at intermediate- or high-risk populations. Bufalin is a cardiac ...
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#10Bufalin - BML-AP303 - Enzo Life Sciences
Bufalin - BML-AP303. ... Bufalin. ATPase inhibitor ... Tiam1 is involved in the regulation of bufalin-induced apoptosis in human leukemia cells: N. Kawazoe, ...
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#11Bufalin | CAS 465-21-4 | SCBT
Bufalin, is a cardiotonic steroid originally isolated from the Chinese toad venom. Experiments have shown Bufalin to have demonstrated apoptotic and cell ...
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#12Preparative Isolation of Bufalin and Cinobufagin from Chinese ...
bufalin ) from the Chinese traditional medicine ChanSu. The crude. ChanSu extract is prepared with solvent refluxing under optimal conditions.
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#13Bufalin 465-21-4 - Sigma-Aldrich
Bufalin (5β,20(22)-Bufadienolide-3β,14-diol ); Buy proteins and enzymes online from Sigma-Aldrich.
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#14Bufalin - ATPase - TargetMol
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated ...
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#15Radiosynthesis and pharmacokinetics of [18F]fluoroethyl ...
Radiosynthesis and Pharmacokinetics of [18F]fluoroethyl bufalin in Hepatocellular Carcinoma bearing Mice Zhaoshuo Yang,1 Jianhua Liu,2 ...
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#16Acetyl-bufalin shows potent efficacy against non-small-cell ...
Cyclin-dependent kinase 9 (CDK9) is a promising prognostic marker and therapeutic target in cancers. Bufalin is an effective anti-tumour ...
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#17Bufalin | C24H34O4 | ChemSpider
Bufalin. Molecular FormulaC24H34O4; Average mass386.524 Da; Monoisotopic mass386.245697 Da; ChemSpider ID7826155. defined stereocentres ...
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#18BUFALIN - Inxight Drugs
Bufalin is a traditional oriental medicines, originally isolated from the Chinese toad venom. Bufalin is a cardiotonic steroid that has the potential to ...
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#19Bufalin-Loaded PEGylated Liposomes: Antitumor Efficacy ...
Bufalin, derived from Venenum Bufonis, exerts antitumor effects but has low bioavailability and adverse effects when administered as a ...
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#20Bufalin, a Traditional Oriental Medicine, Induces Apoptosis in ...
Bufalin is a traditional oriental medicines which induces apoptosis in some lines of human tumor cells. It constitutes the major digoxin-like immunoreactive ...
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#21Bufalin suppresses ovarian cancer cell proliferation via EGF...
Bufalin inhibited phosphorylation of EGFR, protein kinase B (AKT), and extracellular signal-regulated kinase (ERK). Conclusion: Bufalin ...
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#22Bufalin - CAS 465-21-4 - Calbiochem | 203900 - EMD Millipore
Bufalin - CAS 465-21-4 - Calbiochem A cardiotonic steroid isolated from toads of Bufo species that potently inhibits ouabain-sensitive Na+,K+-ATPase ...
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#23Bufalin, a bufanolide steroid from the parotoid glands of the ...
Abstract In this study, we investigated the effect of bufalin on the human ether-à-go-go-related gene (hERG) K+ channels using the ...
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#24Bufalin Induces Cell Death in Human Lung Cancer Cells ...
Bufalin is a key component of a Chinese medicine (Chan Su) and has been proved effective in killing various cancer cells. Its role in inducing DNA damage ...
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#25Synthesis of bufalin - Journal of the Chemical Society D - RSC ...
A new total synthesis of resibufogenin and bufalin using digitoxigenin, represents the first chemical transformation of a cardenolide to a bufadienolide.
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#26Therapeutic Targets of Bufalin on Renal Carcinoma and ...
The possible targets underlying the activity of bufalin on renal cell carcinoma (RCC) were investigated using network pharmacology and experimental ...
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#27Bufalin | Na+/K+ ATPase Inhibitor | MedChemExpress
Bufalin is an active component isolated from Chan Su, acts as a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, ...
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#28Bufalin, Na + /K + -ATPase inhibitor (ab145636) - Abcam
MW 386.52, Purity > 98%. Na+/K+-ATPase inhibitor. Potent steroid receptor coactivators SRC-3 and SRC-1 inhibitor. Induces cell differentiation and apoptosis ...
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#29Bufalin Induces Apoptosis and Improves the Sensitivity of ...
To demonstrate the inhibitory effect of bufalin on glioma cells and glioma stem-like cells (GSCs) and discuss the underlying mechanism, the ...
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#30Anti-tumor Activity of Bufalin by Inhibiting c-MET Mediated ...
Bufalin was found to have an inhibitory effect on the GBC-SD cell growth and reduce the self-renewal and characteristic of gallbladder cancer stem cells. It ...
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#31CHEBI:517248 - bufalin - EMBL-EBI
ChEBI Name, bufalin. ChEBI ID, CHEBI:517248. Definition, A 14β-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at ...
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#32Bufalin down-regulates Axl expression to inhibit cell ...
We observed the inhibitory effect of bufalin on the proliferation of A549 and H460 NSCLC cells and the clonogenicity of these cells was reduced by bufalin ...
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#33Bufalin - CAS 465-21-4 - Calbiochem | 203900 - Merck Millipore
Bufalin - CAS 465-21-4 - Calbiochem A cardiotonic steroid isolated from toads of Bufo species that potently inhibits ouabain-sensitive Na+,K+-ATPase ...
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#34Bufalin | ATPase 抑制剂| 现货供应| 美国品牌
Bufalin 可与Na+/K+-ATPase的亚基α1、α2和α3结合，其Kd值分别为42.5 nM、45 nM和40 nM。Bufalin 是一种从中药蟾酥中分离出来的，具有抗癌活性的，类地高辛免疫反应的主要 ...
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#35Bufalin suppresses endometriosis progression by inducing ...
Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis · Department of Molecular and Cellular Biology, Baylor College of Medicine, ...
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#36465-21-4・Bufalin・029-16981[Detail Information] - FUJIFILM ...
This product is bufalin in Reagents and Test Solutions in the General Tests of the Japanese Pharmacopoeia. It is adapted to assay.
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#37Bufalin suppresses hepatocellular carcinoma invasion and ...
Keywords: bufalin, metastasis, HIF-1α, hepatocellular carcinoma, PI3K/AKT/mTOR ... Bufalin inhibits hepatic tumor metastasis in vivo.
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#38Bufalin definition and meaning | Collins English Dictionary
We then examined the antitumor activity of bufalin in sorafenib-resistant cells. Bo Zhai, Fengli Hu, Haijiang Yan, Dali Zhao, Xin Jin, Taishi ...
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#39Full article: Bufalin induces apoptosis via mitochondrial ROS ...
Our previous study demonstrated that bufalin induced cell death via autophagy in HT-29 and Caco-2 colon cancer cells, but the action of bufalin ...
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#40Bufalin Inhibits the Differentiation and Proliferation of Cancer ...
Establishment of primary osteosarcoma cell line C1OS · Cancer stem cells derived from C1OS cells · Bufalin inhibits the proliferation of C1OS-CSCs.
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#41Bufalin | 465-21-4 | Biosynth Carbosynth
bufalin -induced potential cell death levels inhibition cycle assay cell cycle analysis chinese significantly kinase hepatocellular leukemia medicine
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#42Effect of once daily intraperitoneal injection of bufalin on the ...
Compared with vehicle alone, bufalin significantly delayed LNCaP xenograft tumor growth (Fig. 4B and C) without affecting animal body weights (P > 0.05; Fig. 4A ...
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#43Combination Treatment of Sorafenib and Bufalin Induces ...
However, the efficacy and molecular mechanisms of the two-drug combination (bufalin combined with sorafenib) on inducing apoptosis in NCI-H292 lung cancer cells ...
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#44Blocking autophagy enhances the pro-apoptotic effect of ...
RESULTS · Bufalin suppressed proliferation of HGC cells and induced their cell cycle arrest · Bufalin induced ER stress-mediated apoptosis in HGC ...
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#45Anticancer Effects of Bufalin on Human Hepatocellular ... - MDPI
In good agreement with previous studies, we found that 100 nM bufalin induced extensive HepG2 cell apoptosis. However, we also noticed bufalin triggered ...
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#46Bufalin: A Systematic Review of Research Hotspots ... - X-MOL
Bufalin is an anticancer drug extract from traditional Chinese medicine. Several articles about bufalin have been published.
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#47Bufalin | ≥99%(HPLC) | AdooQ®
Bufalin is an active component isolated from Chan Su, acts as a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, ...
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#48Critical Role of Heat Shock Protein 27 in Bufalin-Induced ...
Our previous study showed that bufalin inhibited growth of human osteosarcoma cell lines U2OS and U2OS/MTX300 in culture. Therefore, this study ...
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#49Structures and characterization of digoxin- and bufalin-bound ...
Thus, for the E2P–bufalin complex, a model of two potassium ions occupying cation-binding sites I and II superimposed well with residual ...
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#50Evidence-based Anticancer Materia Medica
The mechanism of inhibiting the topo IIα may be due to the translocation of CK2 to transmit the bufalin signal to the nucleus, and then formed a complex of ...
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#51Synthesis of bufalin - Arizona State University
A new total synthesis of resibufogenin and bufalin using digitoxigenin, represents the first chemical transformation of a cardenolide to a bufadienolide.
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#52Retraction of “Effect of Bufalin on Proliferation - ProQuest
Retraction of “Effect of Bufalin on Proliferation and Apoptosis of Human Non-small Cell Lung Cancer A549 Cell. Zhongguo Fei Ai Za Zhi, 2010, 13(9): 841-845” ...
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#53Bufalin Induces the Interplay between Apoptosis and ...
Bufalin Induces the Interplay between Apoptosis and Autophagy in Glioma Cells through Endoplasmic Reticulum Stress. Shuying Shen 1, Yi Zhang 1, Zhen Wang 1, ...
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#54Novel augmentation by bufalin of protein kinase C-induced ...
Bufalin, a major active component of the traditional Chinese medicine Chan Su, is known to induce apoptosis in various cancer cells.
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#55Hemodynamic effects of bufalin in the anesthetized dog. - AHA ...
Natriuresis and diuresis were not observed. Thus, bufalin does in fact have some of the physiological properties required to be considered a candidate for the ...
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#56Venom and Toxin as Targeted Therapy - 第 135 頁 - Google 圖書結果
Bufalin Bufalin is a major compound in Chansu, Huachansu, as well as the toxins of other toad species, such as B. marinus. Several studies have demonstrated ...
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#57Effects of low‑dose bufalin combined with ... - X-MOL
由 R Gu 著作 · 2021 · 被引用 1 次 — CRPC xenograft tumors were generated in mice and, subsequently, mice received appropriate doses of bufalin, hydroxycamptothecin or a combination ...
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#58The Cooperative Interaction of Two Different Signaling ...
Pathways in Response to Bufalin Induces Apoptosis in. Human Leukemia U937 Cells*. (Received for publication, December 14, 1995, and in revised form, ...
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#59Blood Proteins—Advances in Research and Application: 2012 ...
Research findings, “Bufalin inhibits platelet-derived growth factorBB-induced mesangial cell proliferation through mediating cell cycle progression,” are ...
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#60Unique Oxidative Metabolism of Bufalin Generates Two ...
Unique Oxidative Metabolism of Bufalin Generates Two Reactive Metabolites That Strongly Inactivate Human Cytochrome P450 3A · Screening Time- ...
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#61Bufalin suppresses ovarian cancer cell proliferation via EGFR ...
Bufalin inhibited the proliferation of SK-OV-3 cells in a dose- and time-dependent manner. Bufalin was confirmed to combine with EGFR protein ...
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#62AACR 2016: Abstracts 2697-5293 - Google 圖書結果
#3031 Bufalin regulates Cbl-b levels in HeLa cells through protein synthesis inhibition. Mariya S. Liyasova, Stanley Lipkowitz. National Cancer Institute ...
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#63Del 'Búfalo' al 'Bufalín', un Frente | Deportes | EL MUNDO
Del 'Búfalo' al 'Bufalín', un Frente · El segundo presunto autor material de la muerte de Jimmy comparte apodo con un líder violento de los ...
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#64Dos detenidos por amenazar de muerte a un testigo del 'caso ...
Tal y como informa el mismo diario, los detenidos son Sergio S.M., alias 'Bufalín', de 24 años y vecino de Alcobendas, y Ramiro G.M., de 33, ...
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#65Human Design 3a The Defin
of Bufalin Generates Two human behavior | Definition, Theories, Characteristics. What Mark Zuckerberg's metaverse means to our humanity ...
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#66The dwarves conv - europe-cities.com
... follow Amsterdam's NL Architects, Hannes Grblacher and Roland Wck from the BOKU village or the French artist Bufalin Benedetto.
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